SLC1A4 and ERVW-1

Number of citations of the paper that reports this interaction (PMID 12050356)
27

Data Source:
HPRD (in vivo, in vitro)

		SLC1A4	ERVW-1
Gene Name		solute carrier family 1 (glutamate/neutral amino acid transporter), member 4	endogenous retrovirus group W, member 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Centrosome Microtubule Organizing Center Intermediate Filament Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Dendrite Melanosome Neuronal Cell Body Extracellular Vesicular Exosome	Plasma Membrane Integral Component Of Membrane Viral Envelope
	Molecular Function	Chloride Channel Activity L-alanine Transmembrane Transporter Activity L-cystine Transmembrane Transporter Activity L-glutamine Transmembrane Transporter Activity L-proline Transmembrane Transporter Activity L-serine Transmembrane Transporter Activity L-threonine Transmembrane Transporter Activity Sodium:dicarboxylate Symporter Activity L-hydroxyproline Transmembrane Transporter Activity
	Biological Process	Ion Transport Chloride Transport Dicarboxylic Acid Transport Amino Acid Transport Glutamine Transport L-alanine Transport L-cystine Transport Proline Transport L-serine Transport Threonine Transport Hydroxyproline Transport Synaptic Transmission, Glutamatergic Proline Transmembrane Transport Cognition Transmembrane Transport Chloride Transmembrane Transport	Syncytium Formation Anatomical Structure Morphogenesis
Pathways		Transport of inorganic cations/anions and amino acids/oligopeptides Amino acid transport across the plasma membrane SLC-mediated transmembrane transport
Drugs		L-Alanine
Diseases
GWAS		Metabolite levels ( 22286219 22916037)
Protein-Protein Interactions		1 interactors: ERVW-1	2 interactors: SLC1A4 SLC1A5
Entrez ID		6509	30816
HPRD ID		02576	05231
Ensembl ID		ENSG00000115902	ENSG00000242950
Uniprot IDs		P43007	D0EYG5 Q9UQF0
PDB IDs
Enriched GO Terms of Interacting Partners?		Syncytium Formation	Glutamine Transport L-serine Transport Neutral Amino Acid Transport L-alpha-amino Acid Transmembrane Transport Dicarboxylic Acid Transport Amino Acid Transmembrane Transport Amino Acid Transport Sodium Ion Transmembrane Transport Extracellular Amino Acid Transport Hydroxyproline Transport Threonine Transport Sodium Ion Transport Carboxylic Acid Transport Organic Acid Transport Anion Transmembrane Transport Organic Anion Transport L-cystine Transport Monovalent Inorganic Cation Transport Anion Transport Proline Transmembrane Transport L-alanine Transport Proline Transport Metal Ion Transport Alanine Transport Cation Transmembrane Transport Cation Transport Ion Transmembrane Transport Viral Entry Into Host Cell Synaptic Transmission, Glutamatergic Entry Into Host Cell Neuron-neuron Synaptic Transmission Transmembrane Transport Ion Transport Interaction With Host Chloride Transmembrane Transport Monocarboxylic Acid Transport Chloride Transport Viral Life Cycle Response To Virus Inorganic Anion Transport Cognition
Tagcloud ?		affymetrix aspartate astrocytes axonal callosum cc corpus cuprizone demyelinated demyelinating demyelination differently excitotoxicity gfap glast glutamate gray ionotropic localizing matter metabotropic mglur2 neurotoxic revealing studying telencephalic transporter transporters white
Tagcloud (Difference) ?		affymetrix aspartate astrocytes axonal callosum cc corpus cuprizone demyelinated demyelinating demyelination differently excitotoxicity gfap glast glutamate gray ionotropic localizing matter metabotropic mglur2 neurotoxic revealing studying telencephalic transporter transporters white
Tagcloud (Intersection) ?