ERVW-1 and SLC1A4

Number of citations of the paper that reports this interaction (PMID 12050356)
27

Data Source:
HPRD (in vivo, in vitro)

		ERVW-1	SLC1A4
Gene Name		endogenous retrovirus group W, member 1	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Viral Envelope	Centrosome Microtubule Organizing Center Intermediate Filament Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Dendrite Melanosome Neuronal Cell Body Extracellular Vesicular Exosome
	Molecular Function		Chloride Channel Activity L-alanine Transmembrane Transporter Activity L-cystine Transmembrane Transporter Activity L-glutamine Transmembrane Transporter Activity L-proline Transmembrane Transporter Activity L-serine Transmembrane Transporter Activity L-threonine Transmembrane Transporter Activity Sodium:dicarboxylate Symporter Activity L-hydroxyproline Transmembrane Transporter Activity
	Biological Process	Syncytium Formation Anatomical Structure Morphogenesis	Ion Transport Chloride Transport Dicarboxylic Acid Transport Amino Acid Transport Glutamine Transport L-alanine Transport L-cystine Transport Proline Transport L-serine Transport Threonine Transport Hydroxyproline Transport Synaptic Transmission, Glutamatergic Proline Transmembrane Transport Cognition Transmembrane Transport Chloride Transmembrane Transport
Pathways			Transport of inorganic cations/anions and amino acids/oligopeptides Amino acid transport across the plasma membrane SLC-mediated transmembrane transport
Drugs			L-Alanine
Diseases
GWAS			Metabolite levels ( 22286219 22916037)
Protein-Protein Interactions		2 interactors: SLC1A4 SLC1A5	1 interactors: ERVW-1
Entrez ID		30816	6509
HPRD ID		05231	02576
Ensembl ID		ENSG00000242950	ENSG00000115902
Uniprot IDs		D0EYG5 Q9UQF0	P43007
PDB IDs
Enriched GO Terms of Interacting Partners?		Glutamine Transport L-serine Transport Neutral Amino Acid Transport L-alpha-amino Acid Transmembrane Transport Dicarboxylic Acid Transport Amino Acid Transmembrane Transport Amino Acid Transport Sodium Ion Transmembrane Transport Extracellular Amino Acid Transport Hydroxyproline Transport Threonine Transport Sodium Ion Transport Carboxylic Acid Transport Organic Acid Transport Anion Transmembrane Transport Organic Anion Transport L-cystine Transport Monovalent Inorganic Cation Transport Anion Transport Proline Transmembrane Transport L-alanine Transport Proline Transport Metal Ion Transport Alanine Transport Cation Transmembrane Transport Cation Transport Ion Transmembrane Transport Viral Entry Into Host Cell Synaptic Transmission, Glutamatergic Entry Into Host Cell Neuron-neuron Synaptic Transmission Transmembrane Transport Ion Transport Interaction With Host Chloride Transmembrane Transport Monocarboxylic Acid Transport Chloride Transport Viral Life Cycle Response To Virus Inorganic Anion Transport Cognition	Syncytium Formation
Tagcloud ?			affymetrix aspartate astrocytes axonal callosum cc corpus cuprizone demyelinated demyelinating demyelination differently excitotoxicity gfap glast glutamate gray ionotropic localizing matter metabotropic mglur2 neurotoxic revealing studying telencephalic transporter transporters white
Tagcloud (Difference) ?			affymetrix aspartate astrocytes axonal callosum cc corpus cuprizone demyelinated demyelinating demyelination differently excitotoxicity gfap glast glutamate gray ionotropic localizing matter metabotropic mglur2 neurotoxic revealing studying telencephalic transporter transporters white
Tagcloud (Intersection) ?