MRPS5 and MGLL

		MRPS5	MGLL
Description		mitochondrial ribosomal protein S5	monoglyceride lipase
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Small Ribosomal Subunit Ribosome Ribonucleoprotein Complex	Cytoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane
	Molecular Function	RNA Binding Structural Constituent Of Ribosome	Phosphatidylcholine Lysophospholipase Activity Protein Binding Hydrolase Activity Protein Homodimerization Activity Monoacylglycerol Lipase Activity Carboxylic Ester Hydrolase Activity
	Biological Process	Translation Mitochondrial Translation	Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Inflammatory Response Regulation Of Signal Transduction Lipid Catabolic Process Arachidonate Metabolic Process Triglyceride Catabolic Process Acylglycerol Catabolic Process Regulation Of Inflammatory Response Regulation Of Sensory Perception Of Pain Monoacylglycerol Catabolic Process Regulation Of Endocannabinoid Signaling Pathway
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control	Acyl chain remodeling of DAG and TAG Triglyceride catabolism Arachidonate production from DAG MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Drugs
Diseases
GWAS			Amyotrophic lateral sclerosis (sporadic) ( 24529757) Carotid intima media thickness x smoking interaction ( 32117412) Femur bone mineral density x serum urate levels interaction ( 34046847) Pars triangularis volume ( 31530798) Refractive error ( 32231278)
Interacting Genes			26 interacting genes: ADRB2 AQP6 CD79A CHGB COQ9 EBAG9 FAM209A FCER1G GEM GOLT1A GPR152 HSD17B13 HTR4 LMNA LTB4R2 MSRB3 PEX12 SDCBP SLC10A6 SLC18A1 SLC66A2 SLC71A2 SLC7A14 STOM TMEM35A TMX2
Entrez ID		64969	11343
HPRD ID		10099	17574
Ensembl ID		ENSG00000144029	ENSG00000074416
Uniprot IDs		A0A8Q3SIP9 P82675	A0A0C4DFN3 B2ZGL7 Q99685
PDB IDs		3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5I 7A5K 7L08 7OG4 7P2E 7PNX 7PNY 7PNZ 7PO0 7PO1 7PO2 7PO3 7QI4 7QI5 7QI6 8ANY 8CSP 8CSQ 8CSR 8CSS 8CST 8CSU 8K2A 8OIR 8OIS 8QRK 8QRL 8QRM 8QRN 8RRI 8XT0 8XT2	3HJU 3JW8 3JWE 3PE6 4UUQ 5ZUN 6AX1 6BQ0 7L4T 7L4U 7L4W 7L50 7PRM 7ZPG 8AQF 8PTC 8PTQ 8PTR 8RVF 9F8A 9F8B 9F8C 9F8D 9FY5
Enriched GO Terms of Interacting Partners?		MHC Class I Protein Binding T Cell Receptor Complex Cytotoxic T Cell Differentiation Coreceptor Activity Cellular Response To Phosphate Starvation Norepinephrine Secretion Unsaturated Fatty Acid Metabolic Process Energy Reserve Metabolic Process Catechol O-methyltransferase Activity Glutamine-fructose-6-phosphate Transaminase (isomerizing) Activity Sensory Perception Of Itch Sneeze Reflex Neuromedin B Receptor Binding Leydig Cell Proliferation Proacrosomal Vesicle Fusion T Cell Receptor Signaling Pathway Habituation Mastication Icosanoid Metabolic Process Renal Sodium Excretion Renal Albumin Absorption Renin Secretion Into Blood Stream Positive Regulation Of Testosterone Secretion Positive Regulation Of Osteoclast Proliferation Positive Regulation Of Respiratory Gaseous Exchange Negative Regulation Of RNA Export From Nucleus Viral Penetration Into Host Nucleus Regulation Of Endocannabinoid Signaling Pathway Cerebellar Cortex Morphogenesis Monoacylglycerol Catabolic Process Antigen Receptor-mediated Signaling Pathway Response To Corticosteroid Dopamine Secretion Mitochondrial Crista Junction MHC Class I Protein Complex Binding Receptor Complex O-methyltransferase Activity Renal Tubular Secretion Renal Protein Absorption Catecholamine Catabolic Process Energy Derivation By Oxidation Of Organic Compounds Norepinephrine Transport Nonassociative Learning Cellular Response To Cocaine Response To Dopamine Dopamine Catabolic Process Catecholamine Secretion UDP-N-acetylglucosamine Biosynthetic Process Carbohydrate Derivative Binding Host Cell
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