SHOX2 and TRIM29

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		SHOX2	TRIM29
Gene Name		short stature homeobox 2	tripartite motif containing 29
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Mitochondrion Nuclear Membrane	Nucleoplasm Cytoplasm Intermediate Filament Cytoskeleton
	Molecular Function	Sequence-specific DNA Binding	P53 Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Skeletal System Development Osteoblast Differentiation Positive Regulation Of Mesenchymal Cell Proliferation Chondrocyte Development Heart Valve Development Cardiac Atrium Morphogenesis Nervous System Development Heart Development Regulation Of Chondrocyte Differentiation Embryonic Forelimb Morphogenesis Positive Regulation Of Smoothened Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Digestive Tract Morphogenesis Positive Regulation Of Skeletal Muscle Fiber Development Positive Regulation Of Axonogenesis Embryonic Skeletal Joint Morphogenesis Cartilage Development Involved In Endochondral Bone Morphogenesis Muscle Tissue Morphogenesis Regulation Of Branching Morphogenesis Of A Nerve	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Negative Regulation Of Protein Localization To Nucleus
Pathways			Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system
Drugs
Diseases
GWAS		Height ( 23563607)	Corneal curvature ( 22969067) Stroke (pediatric) ( 22990015)
Protein-Protein Interactions		3 interactors: CDK4 TRIM29 ZDHHC17	40 interactors: CARD9 CEP70 CRACR2A DMRT1 FBF1 FBXL19 FXR2 GATA1 GCC1 GOLGA2 GTF2E1 HCLS1 HDAC9 HINT1 IKBKG JAKMIP2 KAT5 LZTS2 MAD1L1 MED7 MID2 MLH1 MYO15B PARP1 POLR2D POLR2E PRICKLE3 PRKCA SHOX2 SMAD9 SNAPC1 SP100 TAX1BP3 TRIM11 TRIM23 TRIM27 TRIP6 TSGA10 UBE2I VIM
Entrez ID		6474	23650
HPRD ID		03936	10280
Ensembl ID			ENSG00000137699
Uniprot IDs		O60902	B7Z8U9 E9PRL4 Q14134
PDB IDs			2CSV
Enriched GO Terms of Interacting Partners?			Regulation Of Viral Transcription Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of Viral Transcription Negative Regulation Of Cellular Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Viral Process Regulation Of Viral Process Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Gene Expression Negative Regulation Of Viral Release From Host Cell Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression RNA Metabolic Process Immune System Process Intracellular Signal Transduction Positive Regulation Of Cellular Biosynthetic Process Regulation Of Viral Release From Host Cell Negative Regulation Of Viral Process Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cell Differentiation Regulation Of Cellular Localization Regulation Of Protein Localization DNA-templated Transcription, Initiation Innate Immune Response Organelle Organization Regulation Of Signal Transduction Cellular Macromolecule Biosynthetic Process Spindle Midzone Assembly Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Process Positive Regulation Of Signal Transduction Transcription Elongation From RNA Polymerase II Promoter Response To Stress Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Tagcloud ?		ablated arrhythmias atrioventricular bmp4 contracting cx40 cx43 cx45 eb ebs embryoid hcn4 heartbeat invaluable morphogenetic nkx2 noggin originates pacemaker propagates rhythmic san sinoatrial slowing subsidiary syncytium tbx2 tbx3 tbx5	adenocarcinoma ataxia atdc atm basis candidacy damaging directly ductal improve ionizing leading mapkap mk2 pancreatic pdac phosphorylated poorly radiation radioprotective radioresistance radiosensitize repair ser ser550 telangiectasia therapeutic understood xenograft
Tagcloud (Difference) ?		ablated arrhythmias atrioventricular bmp4 contracting cx40 cx43 cx45 eb ebs embryoid hcn4 heartbeat invaluable morphogenetic nkx2 noggin originates pacemaker propagates rhythmic san sinoatrial slowing subsidiary syncytium tbx2 tbx3 tbx5	adenocarcinoma ataxia atdc atm basis candidacy damaging directly ductal improve ionizing leading mapkap mk2 pancreatic pdac phosphorylated poorly radiation radioprotective radioresistance radiosensitize repair ser ser550 telangiectasia therapeutic understood xenograft
Tagcloud (Intersection) ?