CPEB1 and DYNLRB1

Number of citations of the paper that reports this interaction (PubMedID 12629046)
47

Data Source:
HPRD (in vitro, in vivo)

		CPEB1	DYNLRB1
Description		cytoplasmic polyadenylation element binding protein 1	dynein light chain roadblock-type 1
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GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm Cytoplasm Cytosol Postsynaptic Density Membrane Dendrite Cell Projection Neuron Projection Synapse Ribonucleoprotein Complex	Cytoplasm Centrosome Cytoskeleton Cytoplasmic Dynein Complex Microtubule Cilium Membrane Dynein Complex Ciliary Tip
	Molecular Function	MRNA Regulatory Element Binding Translation Repressor Activity Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Translation Factor Activity, RNA Binding MRNA 3'-UTR AU-rich Region Binding Ribosome Binding Translation Regulator Activity Metal Ion Binding	Microtubule Motor Activity Protein Binding Identical Protein Binding Dynein Intermediate Chain Binding
	Biological Process	MRNA Processing Translation Regulation Of Translation Negative Regulation Of Translation Regulation Of MRNA 3'-end Processing Cellular Response To Insulin Stimulus Cellular Response To Amino Acid Stimulus Cellular Response To Hypoxia Negative Regulation Of Cytoplasmic Translation	Microtubule-based Movement Visual Behavior Positive Regulation Of Intracellular Transport
Pathways			Intraflagellar transport
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Daytime nap ( 33568662) Excessive daytime sleepiness ( 27992416) General cognitive ability ( 29844566) Schizophrenia ( 28991256 30285260) Tourette syndrome ( 30818990)	Alanine aminotransferase levels ( 33547301) Bipolar disorder ( 31043756) Colorectal cancer or advanced adenoma ( 30510241) Fish- and plant-related diet ( 32066663) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Pulse pressure ( 30224653)
Interacting Genes		9 interacting genes: APP AURKA DYNLRB1 EIF4E KIF1B MAP2 PIN1 SLC16A7 SNCA	10 interacting genes: CEBPA CPEB1 CRCP DYNC1I1 DYNC1I2 HSPH1 MAGEA2 MAGEA2B MPHOSPH6 PALS2
Entrez ID		64506	83658
HPRD ID		09553	06203
Ensembl ID		ENSG00000214575	ENSG00000125971
Uniprot IDs		A0A087WXG7 B4DWY2 Q9BZB8	B4DFR2 Q9NP97
PDB IDs		2M13 2MKE 2MKH 2MKK 2N1O	1Z09 2B95 2E8J 2HZ5 6F1T 6F1Z 6F38 6F3A 6RLB 6SC2 7Z8F 8J07 8PR1 8PTK 8RGG 8RGH
Enriched GO Terms of Interacting Partners?		Main Axon Tau Protein Binding Microtubule-based Process Axon Hillock Postsynapse Negative Regulation Of Microtubule Polymerization Positive Regulation Of Mitotic Cell Cycle Regulation Of Presynapse Organization Neuron Projection Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Presynapse Assembly Regulation Of Protein Catabolic Process Molecular Function Activator Activity Regulation Of Neurotransmitter Uptake Cellular Response To Copper Ion Microtubule Amyloid Fibril Formation Microglial Cell Activation Leukocyte Activation Involved In Inflammatory Response Response To Copper Ion Amyloid-beta Complex Regulation Of Amyloid Precursor Protein Catabolic Process Presynapse Dendritic Shaft Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Mitotic Cell Cycle Dendrite Development Eukaryotic Initiation Factor 4G Binding Glutamatergic Synapse Apical Distal Dendrite Negative Regulation Of Microtubule Polymerization Or Depolymerization Cis-trans Isomerase Activity Cytoskeletal Motor Activity Phosphoprotein Binding Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Synaptic Vesicle Transport Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Kinesin Binding Pyruvate Secondary Active Transmembrane Transporter Activity Regulation Of Neuronal Synaptic Plasticity Synapse Organization Microtubule Binding Microtubule Motor Activity Regulation Of Microtubule-based Process	Negative Regulation Of Protein Acetylation Dynein Light Chain Binding Negative Regulation Of Protein Sumoylation Dynein Heavy Chain Binding Positive Regulation Of Ubiquitin-protein Transferase Activity Histone Deacetylase Binding Cytoplasmic Dynein Complex Regulation Of Protein Sumoylation Regulation Of Ubiquitin-protein Transferase Activity DNA-binding Transcription Factor Binding Dynein Complex RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Microtubule Motor Activity Cellular Senescence DNA Polymerase III Complex Microtubule Response To Vitamin B2 C/EBP Complex RNA Polymerase Complex Negative Regulation Of Post-translational Protein Modification Signal Transduction By P53 Class Mediator CHOP-C/EBP Complex Positive Regulation Of Protein Ubiquitination PML Body White Fat Cell Proliferation Calcitonin Gene-related Peptide Receptor Activity Positive Regulation Of Post-translational Protein Modification Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Positive Regulation Of MHC Class I Biosynthetic Process Response To Phenylpropanoid Negative Regulation Of Protein Metabolic Process Regulation Of MHC Class I Biosynthetic Process Transcription Initiation At RNA Polymerase III Promoter
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