SGCB and SLC52A1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SGCB	SLC52A1
Description		sarcoglycan beta	solute carrier family 52 member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Membrane Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Dystroglycan Complex Sarcoglycan Complex Membrane Sarcolemma	Plasma Membrane Membrane
	Molecular Function	Protein Binding	Virus Receptor Activity Protein Binding Riboflavin Transmembrane Transporter Activity
	Biological Process	Muscle Organ Development Response To Glucose Gene Expression Glucose Homeostasis Glucose Import In Response To Insulin Stimulus Muscle Cell Development Cardiac Muscle Cell Development Vascular Associated Smooth Muscle Cell Development	Riboflavin Metabolic Process Riboflavin Transport Symbiont Entry Into Host Cell
Pathways		Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)	Vitamin B2 (riboflavin) metabolism
Drugs
Diseases		Limb-girdle muscular dystrophy (LGMD) Sarcoglycanopathies, including: Limb-girdle muscular dystrophy (LGMD) 2C; Limb-girdle muscular dystrophy (LGMD) 2D; Limb-girdle muscular dystrophy (LGMD) 2E; Limb-girdle muscular dystrophy (LGMD) 2F
GWAS			Age at first sexual intercourse ( 34211149) Keratoconus ( 33649486) Lung adenocarcinoma ( 28604730)
Interacting Genes		22 interacting genes: ADAM33 ADRA1A APOL3 ATP1B4 CLEC7A CMTM5 EHHADH HTR2C LTB4R2 MAL MGST2 NINJ1 PTTG1IP SGCA SGCD SGCG SGCZ SLC52A1 SMIM3 TMEM11 TNF TRIM63	9 interacting genes: AQP6 CREB3L1 GJA8 IFNGR2 SGCB SHISAL1 SLC7A1 TMEM179B TMEM237
Entrez ID		6443	55065
HPRD ID		02942	07432
Ensembl ID		ENSG00000163069	ENSG00000132517
Uniprot IDs		Q16585 Q5U0N0	Q9NWF4
PDB IDs
Enriched GO Terms of Interacting Partners?		Sarcoglycan Complex Dystroglycan Complex Membrane Heart Contraction Muscle Contraction Heart Process Sarcolemma Muscle System Process Circulatory System Process Plasma Membrane Positive Regulation Of Calcium-mediated Signaling Positive Regulation Of Action Potential Cardiac Muscle Tissue Development Negative Regulation Of Heart Rate Dystrophin-associated Glycoprotein Complex Regulation Of Calcium-mediated Signaling Positive Regulation Of Calcineurin-NFAT Signaling Cascade Negative Regulation Of Heart Contraction Negative Regulation Of Blood Circulation Muscle Organ Development Negative Regulation Of Myoblast Differentiation Striated Muscle Tissue Development Negative Regulation Of Heart Rate Involved In Baroreceptor Response To Increased Systemic Arterial Blood Pressure Protein Insertion Into Plasma Membrane Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Ferroptosis Muscle Structure Development Muscle Tissue Development Negative Regulation Of Bile Acid Secretion Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Translational Initiation By Iron Positive Regulation Of Interleukin-33 Production Regulation Of Calcineurin-mediated Signaling Regulation Of Calcineurin-NFAT Signaling Cascade Response To Gram-negative Bacterium Negative Regulation Of Branching Involved In Lung Morphogenesis Positive Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of Nitric Oxide Metabolic Process Detection Of Yeast Detection Of Molecule Of Fungal Origin Positive Regulation Of Inflammatory Response Positive Regulation Of The Force Of Heart Contraction By Epinephrine-norepinephrine Positive Regulation Of Heart Rate By Epinephrine-norepinephrine Positive Regulation Of MAPK Cascade Positive Regulation Of ERK1 And ERK2 Cascade Phospholipase C-activating Adrenergic Receptor Signaling Pathway Regulation Of Action Potential Norepinephrine-epinephrine Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure System Process Long-chain (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity	PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transporter Activity Nitrate Transmembrane Transport Transmembrane Transport Membrane Carbon Dioxide Transmembrane Transport Gap Junction-mediated Intercellular Transport Type II Interferon Receptor Activity Sarcoglycan Complex Dystroglycan Complex Glucose Import In Response To Insulin Stimulus L-lysine Transmembrane Transport Ornithine Transport L-lysine Transmembrane Transporter Activity L-histidine Transmembrane Transporter Activity Lysine Transport L-ornithine Transmembrane Transport L-histidine Transmembrane Transport L-ornithine Transmembrane Transporter Activity L-arginine Import Across Plasma Membrane L-histidine Import Across Plasma Membrane Extracellular Matrix Constituent Secretion Cytoplasmic Vesicle Membrane Cone Photoreceptor Outer Segment Monoatomic Anion Channel Activity Ammonium Transmembrane Transport Ammonium Channel Activity Renal Water Transport Intercellular Transport Positive Regulation Of Glutamate Receptor Signaling Pathway Type III Interferon-mediated Signaling Pathway Basic Amino Acid Transmembrane Transporter Activity Aromatic Amino Acid Transport L-arginine Transmembrane Transporter Activity Rod Photoreceptor Outer Segment
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