SFTPD and GPA33

		SFTPD	GPA33
Description		surfactant protein D	glycoprotein A33
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space Cytoplasm Lysosome Multivesicular Body Endoplasmic Reticulum Membrane Endocytic Vesicle Clathrin-coated Endocytic Vesicle	Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Protein Binding Carbohydrate Binding Identical Protein Binding	Protein Binding Signaling Receptor Activity
	Biological Process	Regulation Of Cytokine Production Immune System Process Regulation Of Immune System Process Receptor-mediated Endocytosis Respiratory Gaseous Exchange By Respiratory System Negative Regulation Of Interleukin-2 Production Negative Regulation Of T Cell Proliferation Defense Response To Bacterium Surfactant Homeostasis Innate Immune Response Macrophage Chemotaxis Lung Alveolus Development Positive Regulation Of Phagocytosis Reactive Oxygen Species Metabolic Process
Pathways		Toll Like Receptor 4 (TLR4) Cascade Toll Like Receptor TLR1:TLR2 Cascade Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Signal regulatory protein family interactions Surfactant metabolism Regulation of TLR by endogenous ligand Defective CSF2RB causes SMDP5 Defective CSF2RA causes SMDP4 SARS-CoV-1 activates/modulates innate immune responses SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs		Beta-D-Glucose
Diseases
GWAS		Chronic obstructive pulmonary disease ( 28166215 30804561 33909500) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Lung function (FEV1/FVC) ( 30804560) Rheumatoid arthritis ( 24390342 30423114)	Eosinophilic granulomatosis with polyangiitis (ANCA negative) ( 31719529)
Interacting Genes		3 interacting genes: DCN DMBT1 MFAP4	8 interacting genes: EMP3 ENTPD3 MALL NRSN1 NSG1 POT1 SMCO4 UPK2
Entrez ID		6441	10223
HPRD ID		01522	03704
Ensembl ID		ENSG00000133661	ENSG00000143167
Uniprot IDs		P35247	Q99795
PDB IDs		1B08 1M7L 1PW9 1PWB 2GGU 2GGX 2ORJ 2ORK 2OS9 2RIA 2RIB 2RIC 2RID 2RIE 3DBZ 3G81 3G83 3G84 3IKN 3IKP 3IKQ 3IKR 4E52 4M17 4M18 5OXR 5OXS
Enriched GO Terms of Interacting Partners?		Extracellular Space Extracellular Matrix Extracellular Region Extracellular Matrix Binding	Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Postsynaptic Neurotransmitter Receptor Cycle Neurotransmitter Receptor Cycle
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?