MPP4 and MPP5

Number of citations of the paper that reports this interaction (PMID 15914641)
14

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		MPP4	MPP5
Gene Name		membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Presynaptic Membrane Intracellular Membrane-bounded Organelle	Nucleoplasm Cytoplasm Plasma Membrane Tight Junction Endomembrane System Myelin Sheath Adaxonal Region Lateral Loop Schmidt-Lanterman Incisure Protein Complex Extracellular Vesicular Exosome
	Molecular Function		Protein Binding Protein Domain Specific Binding
	Biological Process	Protein Localization To Synapse	Morphogenesis Of An Epithelial Sheet Peripheral Nervous System Myelin Maintenance Myelin Assembly Cell Junction Assembly Protein Localization To Myelin Sheath Abaxonal Region Cell-cell Junction Organization Tight Junction Assembly Establishment Of Protein Localization To Plasma Membrane
Pathways			Cell junction organization Cell-cell junction organization Tight junction interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: FASLG MPP5	6 interactors: ARF6 CRB3 INADL LIN7A MPP4 PARD6B
Entrez ID		58538	64398
HPRD ID		07360	09508
Ensembl ID		ENSG00000082126	ENSG00000072415
Uniprot IDs		E7ET46 E9PG92 F6Q0Y6 Q96JB8	Q658X5 Q8N3R9
PDB IDs			1Y76 3UIT
Enriched GO Terms of Interacting Partners?		Protein Localization To Myelin Sheath Abaxonal Region Endosomal Lumen Acidification Retinal Cell Programmed Cell Death Endomembrane System Organization Necroptotic Signaling Pathway Cellular Chloride Ion Homeostasis Inflammatory Cell Apoptotic Process Chloride Ion Homeostasis Positive Regulation Of Endothelial Cell Apoptotic Process T Cell Apoptotic Process Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Intracellular PH Reduction Peripheral Nervous System Myelin Maintenance PH Reduction Positive Regulation Of ERBB Signaling Pathway Asymmetric Protein Localization Endosome Organization Myelin Assembly Necroptotic Process Myelin Maintenance Regulation Of Endothelial Cell Apoptotic Process Developmental Programmed Cell Death Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Intracellular PH Programmed Necrotic Cell Death Anion Homeostasis Myelination In Peripheral Nervous System Regulation Of Cellular PH Necrotic Cell Death Tight Junction Assembly Schwann Cell Development Positive Regulation Of Neuron Apoptotic Process Morphogenesis Of An Epithelial Sheet Schwann Cell Differentiation Cell Development Regulation Of PH Apical Junction Assembly Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Neuron Death Establishment Of Protein Localization To Plasma Membrane Regulation Of ERBB Signaling Pathway Negative Regulation Of Angiogenesis Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Glial Cell Development Extrinsic Apoptotic Signaling Pathway Zymogen Activation Peripheral Nervous System Development Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process	Tight Junction Assembly Apical Junction Assembly Cell-cell Junction Assembly Establishment Or Maintenance Of Cell Polarity Cell Junction Assembly Cell-cell Junction Organization Cellular Component Assembly Protein Localization Protein Localization To Plasma Membrane Protein Localization To Basolateral Plasma Membrane Plasma Membrane Organization Maintenance Of Epithelial Cell Apical/basal Polarity Maintenance Of Apical/basal Cell Polarity Myeloid Cell Apoptotic Process Protein Localization To Endosome Maintenance Of Cell Polarity Cellular Protein Localization Protein Localization To Membrane Establishment Of Epithelial Cell Polarity Cell Division Endomembrane System Organization Protein Localization To Cell Surface Protein Localization To Synapse Negative Regulation Of Receptor-mediated Endocytosis Hepatocyte Apoptotic Process Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Plasma Membrane Cortical Actin Cytoskeleton Organization Asymmetric Protein Localization Establishment Or Maintenance Of Apical/basal Cell Polarity Cortical Cytoskeleton Organization Regulation Of Rac Protein Signal Transduction Ruffle Organization Regulation Of Establishment Of Protein Localization To Plasma Membrane Negative Regulation Of Endocytosis Regulation Of Filopodium Assembly Regulation Of Dendritic Spine Development Regulation Of Protein Localization To Plasma Membrane
Tagcloud ?		adherens colocalized crb1 crumbs dlg1 glia guanylate implicate junctions mpp3 mpp5 muller olm organize outer palmitoylated photoreceptor pigmentosa pinpoint plexiform polarity retina retinae retinitis retinopathies scaffold subapical synapse unrecognized	contextdependent crossroads fat1 fat2 fat3 fat4 fathippo frmd1 frmd6 gammasecretase lamellipodia membraneassociated mob1a mob1b mpdz mupp1 pals1 preball prognostics sav1 scribblebinding stemcell stk3 stk4 vapsbinding wwc1 wwc2 wwtr1 yap1
Tagcloud (Difference) ?		adherens colocalized crb1 crumbs dlg1 glia guanylate implicate junctions mpp3 muller olm organize outer palmitoylated photoreceptor pigmentosa pinpoint plexiform polarity retina retinae retinitis retinopathies scaffold subapical synapse unrecognized	contextdependent crossroads fat1 fat2 fat3 fat4 fathippo frmd1 frmd6 gammasecretase lamellipodia membraneassociated mob1a mob1b mpdz mupp1 pals1 preball prognostics sav1 scribblebinding stemcell stk3 stk4 vapsbinding wwc1 wwc2 wwtr1 yap1
Tagcloud (Intersection) ?		mpp5