MPP4 and PALS1

Number of citations of the paper that reports this interaction (PubMedID 15914641)
0

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		MPP4	PALS1
Description		MAGUK p55 scaffold protein 4	protein associated with LIN7 1, MAGUK p55 family member
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Adherens Junction Actin Cytoskeleton Protein-containing Complex	Cytoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Plasma Membrane Adherens Junction Bicellular Tight Junction Endomembrane System Membrane Apical Plasma Membrane Axon Protein-containing Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Myelin Sheath Adaxonal Region Cell Projection Perikaryon Lateral Loop Schmidt-Lanterman Incisure Apical Junction Complex Apical Part Of Cell Extracellular Exosome Anchoring Junction
	Molecular Function	Protein Binding	Nucleotide Binding Protein Binding ATP Binding Protein Domain Specific Binding Identical Protein Binding
	Biological Process	Protein Localization To Synapse	Morphogenesis Of An Epithelial Sheet Plasma Membrane Organization Intracellular Protein Localization Gene Expression Establishment Or Maintenance Of Polarity Of Embryonic Epithelium Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Central Nervous System Neuron Development Cerebral Cortex Development Peripheral Nervous System Myelin Maintenance Myelin Assembly Protein Localization To Myelin Sheath Abaxonal Region Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Generation Of Neurons Protein Localization To Plasma Membrane
Pathways			Tight junction interactions SARS-CoV-1 targets PDZ proteins in cell-cell junction SARS-CoV-2 targets PDZ proteins in cell-cell junction SARS-CoV-2 targets PDZ proteins in cell-cell junction
Drugs
Diseases
GWAS		Anthracycline-induced cardiotoxicity in early breast cancer ( 32378780) Tau burden ( 33426524) White matter microstructure in first episode schizophrenia (left inferior parietal cortex) ( 28924203)
Interacting Genes		3 interacting genes: FASLG PALS1 PLEKHF2	14 interacting genes: ARF6 CRB3 DLGAP4 FTCD GPRASP3 LIN7A MPP4 NUMB PARD6B PATJ SNTG2 SOCS4 SRGAP2B TRAF2
Entrez ID		58538	64398
HPRD ID		07360	09508
Ensembl ID		ENSG00000082126	ENSG00000072415
Uniprot IDs		A0A087WUS1 Q96JB8	Q8N3R9
PDB IDs			1Y76 3UIT 4UU5 4UU6 4WSI 7M4R 7NTJ 7NTK 7QCS
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Phospholipid Translocation Cytoplasmic Vesicle Lumen Retinal Cell Programmed Cell Death Positive Regulation Of Phosphatidylserine Exposure On Apoptotic Cell Surface Establishment Or Maintenance Of Polarity Of Embryonic Epithelium Protein Localization To Myelin Sheath Abaxonal Region Endomembrane System Lateral Loop Myelin Sheath Adaxonal Region Inflammatory Cell Apoptotic Process Necroptotic Signaling Pathway Release Of Sequestered Calcium Ion Into Cytosol By Endoplasmic Reticulum Intracellular Chloride Ion Homeostasis Schmidt-Lanterman Incisure Peripheral Nervous System Myelin Maintenance Positive Regulation Of Phospholipid Transport Endosomal Lumen Acidification Necroptotic Process Myelin Maintenance Myelin Assembly Regulation Of Plasma Membrane Organization Death Receptor Binding Chloride Ion Homeostasis Programmed Necrotic Cell Death Monoatomic Anion Homeostasis Morphogenesis Of An Epithelial Sheet Generation Of Neurons Programmed Cell Death Involved In Cell Development Positive Regulation Of Endothelial Cell Apoptotic Process Membrane Organization T Cell Apoptotic Process Apical Junction Complex Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Tumor Necrosis Factor Receptor Binding Positive Regulation Of ERBB Signaling Pathway Lymphocyte Apoptotic Process Cytoplasmic Vesicle	Apical Part Of Cell Regulation Of Cell Junction Assembly Regulation Of Synapse Organization Bicellular Tight Junction Regulation Of Synapse Assembly Establishment Or Maintenance Of Cell Polarity Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Thioesterase Binding Cell Junction Organization Regulation Of Cellular Component Organization Apical Junction Complex Anchoring Junction Cell Cortex Cell-cell Junction Organization Tight Junction Cell Division Cell Junction Positive Regulation Of Cellular Component Biogenesis Erythrocyte Apoptotic Process TORC2 Complex Disassembly Glutamate Formimidoyltransferase Activity Formimidoyltetrahydrofolate Cyclodeaminase Activity Extracellular Exosome Regulation Of Dendritic Spine Development Glutamatergic Synapse Plasma Membrane TRAF2-GSTP1 Complex TORC1 Complex Assembly CD40 Receptor Binding L-histidine Catabolic Process To Glutamate And Formate L-histidine Catabolic Process To Glutamate And Formamide Signaling Adaptor Activity Protein Localization To Cleavage Furrow Neuroblast Division In Subventricular Zone L27 Domain Binding Subapical Complex
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