PDLIM2 and ZNF695

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PDLIM2	ZNF695
Description		PDZ and LIM domain 2	zinc finger protein 695
Image			No pdb structure
GO Annotations	Cellular Component	Stress Fiber Nucleus Cytoplasm Cytoskeleton Adherens Junction Z Disc Filamentous Actin	Nucleus
	Molecular Function	Actin Binding Protein Binding Ubiquitin Protein Ligase Binding Metal Ion Binding Muscle Alpha-actinin Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Heart Development Actin Cytoskeleton Organization Protein Catabolic Process Muscle Structure Development	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription
Pathways
Drugs
Diseases
GWAS		Parkinson's disease ( 28892059) Platelet count ( 32888494) Plateletcrit ( 32888494) Refractive error ( 32231278) Survival in breast cancer (estrogen-receptor positive) ( 29423119)	Femur bone mineral density x serum urate levels interaction ( 34046847) Metabolite levels ( 23823483)
Interacting Genes		14 interacting genes: ACD APC AURKA BAG4 BCAR3 FGFR2 FGFR4 MKRN2 POT1 RAF1 TGFB1 UBC UBE2E2 ZNF695	2 interacting genes: MEOX2 PDLIM2
Entrez ID		64236	57116
HPRD ID		17831	11534
Ensembl ID		ENSG00000120913	ENSG00000197472
Uniprot IDs		Q96JY6	Q8IW36
PDB IDs		2PA1 3PDV
Enriched GO Terms of Interacting Partners?		Enzyme-linked Receptor Protein Signaling Pathway Fibroblast Growth Factor Receptor Activity Telomerase Inhibitor Activity Shelterin Complex Telomere Assembly Establishment Of Protein Localization To Telomere Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of MAPK Cascade Nuclear Telomere Cap Complex Negative Regulation Of Chromosome Organization Negative Regulation Of Macromolecule Metabolic Process Insulin Receptor Signaling Pathway Modification-dependent Protein Catabolic Process Negative Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Branch Elongation Of An Epithelium Gland Development Regulation Of Intracellular Signal Transduction Positive Regulation Of DNA Metabolic Process Regulation Of DNA Biosynthetic Process Positive Regulation Of Fibroblast Migration Telomere Capping Ubiquitin Protein Ligase Binding Positive Regulation Of Cellular Component Organization Regulation Of Signal Transduction Protein-containing Complex Binding Regulation Of Primary Metabolic Process Macromolecule Metabolic Process Proteolysis Involved In Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Metabolic Process Protein Metabolic Process Protein Modification Process Fibroblast Growth Factor Binding Protein Phosphorylation Protein Autophosphorylation Positive Regulation Of Cell Cycle Axis Elongation Regulation Of MAPK Cascade Positive Regulation Of Mitotic Cell Cycle Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Via Telomerase Positive Regulation Of Intracellular Signal Transduction Negative Regulation Of Cellular Component Organization Positive Regulation Of Macromolecule Metabolic Process Developmental Growth Involved In Morphogenesis Regulation Of Extracellular Matrix Disassembly RNA-templated DNA Biosynthetic Process Regulation Of Organelle Organization Phosphorylation	Segment Specification Somite Development Somite Specification Muscle Alpha-actinin Binding
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