RRAGC and RRAGA

Number of citations of the paper that reports this interaction (PubMedID 11073942)
0

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		RRAGC	RRAGA
Description		Ras related GTP binding C	Ras related GTP binding A
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Lysosome Lysosomal Membrane Cytosol Membrane Gtr1-Gtr2 GTPase Complex FNIP-folliculin RagC/D GAP	Nucleus Nucleoplasm Cytoplasm Lysosome Lysosomal Membrane Cytosol Membrane GATOR1 Complex Gtr1-Gtr2 GTPase Complex FNIP-folliculin RagC/D GAP
	Molecular Function	Nucleotide Binding Magnesium Ion Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Protein-membrane Adaptor Activity Protein Heterodimerization Activity GTPase Binding Molecular Adaptor Activity Enzyme-substrate Adaptor Activity	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity Ubiquitin Protein Ligase Binding Protein Homodimerization Activity Protein-membrane Adaptor Activity Protein Heterodimerization Activity Phosphoprotein Binding
	Biological Process	Autophagosome Assembly Cytoplasmic Translation DNA-templated Transcription Apoptotic Process Lysosome Organization Small GTPase-mediated Signal Transduction Intracellular Protein Localization RNA Splicing Cellular Response To Starvation Negative Regulation Of Autophagy SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Destabilization Cellular Response To Nutrient Levels Regulation Of TOR Signaling Cellular Response To Amino Acid Starvation TORC1 Signaling Response To Amino Acid Negative Regulation Of Translational Initiation Positive Regulation Of Translational Initiation Protein Localization To Lysosome Cellular Response To Amino Acid Stimulus Protein Localization To Membrane Negative Regulation Of Protein Localization To Nucleus Regulation Of TORC1 Signaling Positive Regulation Of TORC1 Signaling	Autophagosome Assembly Cytoplasmic Translation Apoptotic Process Intracellular Protein Localization Cellular Response To Starvation Negative Regulation Of Autophagy Cellular Response To Nutrient Levels Positive Regulation Of TOR Signaling Tumor Necrosis Factor-mediated Signaling Pathway Cellular Response To Amino Acid Starvation Intracellular Signal Transduction TORC1 Signaling Glucose Homeostasis Negative Regulation Of Translational Initiation Positive Regulation Of Translational Initiation Cellular Response To Methionine Protein Localization To Lysosome Cellular Response To Amino Acid Stimulus Protein Localization To Membrane Positive Regulation Of TORC1 Signaling
Pathways		Macroautophagy MTOR signalling mTORC1-mediated signalling Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes Regulation of PTEN gene transcription Amino acids regulate mTORC1	Macroautophagy MTOR signalling mTORC1-mediated signalling Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes E3 ubiquitin ligases ubiquitinate target proteins Regulation of PTEN gene transcription Amino acids regulate mTORC1
Drugs
Diseases
GWAS		Beard thickness ( 26926045)
Interacting Genes		7 interacting genes: ATXN1L DEPDC5 MPP3 NOL8 RRAGA RRAGB WNT2	5 interacting genes: DYNLT1 FLCN IL7R NOL8 RRAGC
Entrez ID		64121	10670
HPRD ID		12198	10205
Ensembl ID		ENSG00000116954	ENSG00000155876
Uniprot IDs		B4DQ03 B4DQG4 Q9HB90	Q7L523
PDB IDs		3LLU 6CES 6EHR 6NZD 6S6A 6S6D 6SB0 6SB2 6U62 6ULG 6WJ2 6WJ3 7T3A 7T3B 7T3C 7UX2 7UXC 7UXH 8DHB	5X6V 6CES 6EHR 6NZD 6S6A 6S6D 6SB0 6SB2 6U62 6ULG 6WJ2 6WJ3 7T3A 7T3B 7T3C 7UX2 7UXC 7UXH 8DHB
Enriched GO Terms of Interacting Partners?		Cellular Response To Amino Acid Starvation Response To Amino Acid Starvation Positive Regulation Of TORC1 Signaling GATOR1 Complex Gtr1-Gtr2 GTPase Complex Positive Regulation Of TOR Signaling Regulation Of TORC1 Signaling Regulation Of TOR Signaling Cellular Response To Starvation Response To Starvation Cellular Response To Nutrient Levels Negative Regulation Of Translational Initiation Positive Regulation Of Translational Initiation Protein Localization To Lysosome TORC1 Signaling Lysosomal Membrane Regulation Of Autophagy Guanyl Ribonucleotide Binding Cellular Response To Amino Acid Stimulus TOR Signaling Protein Localization To Vacuole Response To Nutrient Levels Lysosome Regulation Of Translational Initiation Negative Regulation Of Autophagy Response To Amino Acid Cytoplasmic Translation Lung Induction Protein Localization To Organelle POZ Domain Binding Positive Regulation Of Translation Cell Proliferation In Midbrain Epithelial Cell Proliferation Involved In Lung Morphogenesis Regulation Of Branching Involved In Lung Morphogenesis Negative Regulation Of Translation Cellular Response To Methionine Atrial Cardiac Muscle Tissue Morphogenesis Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Response To Methionine Intracellular Protein Localization Iris Morphogenesis FNIP-folliculin RagC/D GAP Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Positive Regulation Of Hematopoietic Stem Cell Proliferation Mammary Gland Epithelium Development Protein Localization To Nucleolus Wnt Signalosome Midbrain Dopaminergic Neuron Differentiation Cellular Response To Leucine Starvation GTPase Activity	FNIP-folliculin RagC/D GAP Lysosome Organization Negative Regulation Of Protein Localization To Nucleus Cellular Response To Amino Acid Starvation Response To Amino Acid Starvation Positive Regulation Of TORC1 Signaling Protein Destabilization SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process TORC1 Signaling Transport Of Viral Material Towards Nucleus Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus Positive Regulation Of TOR Signaling TOR Signaling Regulation Of TORC1 Signaling Interleukin-7 Receptor Activity Intracellular Transport Of Viral Protein In Host Cell Regulation Of TOR Signaling Regulation Of Protein Localization To Nucleus Hemopoiesis Vacuole Organization Cellular Response To Starvation Gtr1-Gtr2 GTPase Complex Negative Regulation Of Lysosome Organization Negative Regulation Of Cell Proliferation Involved In Kidney Development Negative Regulation Of Brown Fat Cell Differentiation Negative Regulation Of Protein Localization Response To Starvation Spindle Interleukin-7-mediated Signaling Pathway Positive Regulation Of T Cell Differentiation In Thymus Intracellular Transport Of Virus Cellular Response To Nutrient Levels Regulation Of Pro-B Cell Differentiation Host Cell Secretory Vesicle Negative Regulation Of T Cell Mediated Cytotoxicity Cell Proliferation Involved In Kidney Development Protein Localization To Nucleolus Regulation Of Lymphoid Progenitor Cell Differentiation Regulation Of Signal Transduction Lysosomal Membrane Regulation Of Protein Stability Regulation Of Autophagy Regulation Of Lysosome Organization Negative Regulation Of Catabolic Process Enzyme-substrate Adaptor Activity Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
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