NPFFR1 and TCP11

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NPFFR1	TCP11
Description		neuropeptide FF receptor 1	t-complex 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cilium Membrane	Acrosomal Vesicle Cilium Membrane Cytoplasmic Vesicle Motile Cilium Sperm Flagellum Cell Projection Sperm Midpiece
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Neuropeptide Receptor Activity	Protein Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Cellular Response To Hormone Stimulus	Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Germ Cell Development Spermatogenesis Protein Kinase A Signaling Cell Differentiation Regulation Of Sperm Capacitation
Pathways		Orexin and neuropeptides FF and QRFP bind to their respective receptors G alpha (q) signalling events
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 23007406) Body size at age 10 ( 32376654) Cognitive decline rate in late mild cognitive impairment ( 26252872) Squamous cell lung carcinoma ( 28604730)	Asthma ( 30929738) Asthma (childhood onset) ( 30929738) Body size at age 10 ( 32376654) Brain morphology (MOSTest) ( 32665545) HDL cholesterol levels ( 32203549) Height ( 18391951 28552196) Hip circumference adjusted for BMI ( 34021172) Liver enzyme levels (alkaline phosphatase) ( 33972514) Subcortical volume (MOSTest) ( 32665545) Systemic lupus erythematosus ( 28714469)
Interacting Genes		3 interacting genes: NPFF TCP11 UBC	13 interacting genes: AIMP2 APP FANCF GRAPL GSTZ1 IKBKG KRTAP13-3 LMBRD1 MAP2K1 MED28 NPFFR1 VAV2 ZNF688
Entrez ID		64106	6954
HPRD ID		12120	01749
Ensembl ID		ENSG00000148734	ENSG00000124678
Uniprot IDs		Q9GZQ6	A0A6E1WXZ9 B7ZAT8 Q8WWU5
PDB IDs
Enriched GO Terms of Interacting Partners?		Vesicle Neuropeptide Activity Somatostatin Secretion Vasopressin Secretion Regulation Of Sperm Capacitation Protein Kinase A Signaling Negative Regulation Of Appetite Negative Regulation Of Heart Rate Protein Tag Activity Regulation Of Response To Food Acute Inflammatory Response To Antigenic Stimulus Regulation Of Cell Maturation Negative Regulation Of Blood Circulation Neuronal Dense Core Vesicle Negative Regulation Of Heart Contraction Regulation Of Appetite G Protein-coupled Receptor Signaling Pathway Neuropeptide Hormone Activity Spinal Cord Development Regulation Of Response To Nutrient Levels Inflammatory Response To Antigenic Stimulus Maternal Process Involved In Female Pregnancy Positive Regulation Of Blood Pressure Negative Regulation Of Insulin Secretion Negative Regulation Of Peptide Secretion
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?