NPFFR1

Gene Name		neuropeptide FF receptor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	G-protein Coupled Receptor Activity Neuropeptide Receptor Activity Peptide Binding
	Biological Process	Neuropeptide Signaling Pathway Synaptic Transmission Biological_process Cellular Response To Hormone Stimulus Response To Peptide
Pathways		G alpha (q) signalling events Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Class A/1 (Rhodopsin-like receptors) Orexin and neuropeptides FF and QRFP bind to their respective receptors GPCR ligand binding Metabolic disorders of biological oxidation enzymes G alpha (q) signalling events GPCR downstream signaling Peptide ligand-binding receptors Gastrin-CREB signalling pathway via PKC and MAPK
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 23007406)
Protein-protein Interactions		1 interactors: NPFF
Entrez ID		64106
HPRD ID		12120
Ensembl ID
Uniprot IDs		Q9GZQ6
PDB IDs
Enriched GO Terms of Interacting Partners?		Somatostatin Secretion Vasopressin Secretion Acute Inflammatory Response To Antigenic Stimulus Negative Regulation Of Heart Rate Negative Regulation Of Appetite Regulation Of Response To Food Regulation Of Appetite Negative Regulation Of Heart Contraction Regulation Of Sensory Perception Of Pain Inflammatory Response To Antigenic Stimulus Regulation Of Membrane Depolarization Positive Regulation Of Blood Pressure Negative Regulation Of Insulin Secretion Response To Morphine Negative Regulation Of Peptide Secretion Regulation Of Neurological System Process Negative Regulation Of Hormone Secretion Peptide Hormone Secretion Peptide Secretion Regulation Of Excitatory Postsynaptic Membrane Potential Acute Inflammatory Response Regulation Of Heart Rate Regulation Of Postsynaptic Membrane Potential Maternal Process Involved In Female Pregnancy Hormone Secretion Hormone Transport Response To Ammonium Ion Peptide Transport Neuropeptide Signaling Pathway Negative Regulation Of Protein Secretion Spinal Cord Development Membrane Depolarization Amide Transport Response To Alkaloid Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Ion Homeostasis Negative Regulation Of Secretion By Cell Regulation Of Heart Contraction Regulation Of Blood Pressure Negative Regulation Of Secretion Negative Regulation Of Protein Transport Cytosolic Calcium Ion Homeostasis Regulation Of Insulin Secretion Regulation Of Peptide Hormone Secretion Female Pregnancy Regulation Of Hormone Secretion Regulation Of Hormone Levels Regulation Of Membrane Potential Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis
Tagcloud ?		amide analgesic arg carboxyl constitute emerging encoded kiss1r kisspeptin modulation modulatory mostly neuropeptide neuropeptides nh2 nociception opiates peptides phe prolactin pyroglutamylated qrfpr releasing reproduction rf rodents share