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ZBED8 and MBTPS1
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
ZBED8
MBTPS1
Gene Name
zinc finger, BED-type containing 8
membrane-bound transcription factor peptidase, site 1
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Golgi Membrane
Endoplasmic Reticulum Lumen
Endoplasmic Reticulum Membrane
Golgi Apparatus
Golgi Stack
Integral Component Of Membrane
Molecular Function
Nucleic Acid Binding
Serine-type Endopeptidase Activity
Biological Process
Proteolysis
Lipid Metabolic Process
Activation Of Signaling Protein Activity Involved In Unfolded Protein Response
Lysosome Organization
Cholesterol Metabolic Process
Endoplasmic Reticulum Unfolded Protein Response
Membrane Protein Intracellular Domain Proteolysis
Response To Endoplasmic Reticulum Stress
Regulation Of Transcription Factor Import Into Nucleus
Cellular Protein Metabolic Process
Small Molecule Metabolic Process
Pathways
Regulation of cholesterol biosynthesis by SREBP (SREBF)
Metabolism of lipids and lipoproteins
ATF6-alpha activates chaperones
Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Protein-Protein Interactions
6 interactors:
EED
EEF1G
HSF4
KIAA1377
MBTPS1
NAB2
10 interactors:
ATF6B
BDNF
BIRC3
C11orf58
CANX
CDK2AP2
SPHK1
TNFRSF14
TNFSF11
ZBED8
Entrez ID
63920
8720
HPRD ID
17430
04522
Ensembl ID
ENSG00000221886
ENSG00000140943
Uniprot IDs
Q8IZ13
Q14703
PDB IDs
Enriched GO Terms of Interacting Partners
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Negative Regulation Of Transcription From RNA Polymerase III Promoter
Negative Regulation Of Transcription, DNA-templated
Histone H3-K9 Demethylation
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Histone H3-K27 Methylation
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Regulation Of Histone H3-K27 Methylation
Organelle Organization
Histone Modification
Membrane Protein Intracellular Domain Proteolysis
Protein Homotrimerization
Positive Regulation Of Protein Modification Process
Cellular Response To Tumor Necrosis Factor
Response To Tumor Necrosis Factor
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Phosphorylation
Positive Regulation Of Cellular Metabolic Process
Regulation Of Phosphorus Metabolic Process
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Response To Cytokine
Positive Regulation Of Protein Phosphorylation
Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Phosphorylation
Positive Regulation Of Secretion
Cellular Response To Organic Substance
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Metabolic Process
Response To Stress
Regulation Of Protein Phosphorylation
Signaling
Regulation Of Protein Metabolic Process
Cell Communication
Response To Anesthetic
Positive Regulation Of Corticotropin-releasing Hormone Secretion
Response To Fluoxetine
Response To L-glutamate
Sphingoid Catabolic Process
Positive Regulation Of Cell Development
Response To Organic Substance
Defense Response
Regulation Of Corticotropin-releasing Hormone Secretion
Positive Regulation Of ERK1 And ERK2 Cascade Via TNFSF11-mediated Signaling
TNFSF11-mediated Signaling Pathway
Positive Regulation Of Fever Generation By Positive Regulation Of Prostaglandin Secretion
Positive Regulation Of NF-kappaB Transcription Factor Activity
Cellular Response To Cytokine Stimulus
Positive Regulation Of Protein Ubiquitination
Regulation Of Secretion
Taste Bud Development
Dendrite Extension
Cellular Response To Norepinephrine Stimulus
Regulation Of Retinal Cell Programmed Cell Death
Positive Regulation Of Cytokine Secretion Involved In Immune Response
Positive Regulation Of Osteoclast Development
Positive Regulation Of Transport
Cell Surface Receptor Signaling Pathway
Osteoclast Proliferation
Axon Target Recognition
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
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Tagcloud (Intersection)
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