CCR3 and CCL3L1

Number of citations of the paper that reports this interaction (PubMedID 11449371)
0

Data Source:
HPRD (in vitro, in vivo)

		CCR3	CCL3L1
Description		C-C motif chemokine receptor 3	C-C motif chemokine ligand 3 like 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane External Side Of Plasma Membrane Membrane	Extracellular Region Extracellular Space
	Molecular Function	G Protein-coupled Receptor Activity Chemokine Receptor Activity Protein Binding C-C Chemokine Receptor Activity C-C Chemokine Binding	Cytokine Activity Protein Binding Chemokine Activity CCR Chemokine Receptor Binding
	Biological Process	Positive Regulation Of Endothelial Cell Proliferation Chemotaxis Inflammatory Response Immune Response Cellular Defense Response Cell Adhesion Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Positive Regulation Of Angiogenesis Cell Chemotaxis Chemokine-mediated Signaling Pathway Cellular Response To Cytokine Stimulus	Chemotaxis Inflammatory Response Immune Response Negative Regulation Of Cell Population Proliferation Positive Regulation Of Cell Migration Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Chemokine receptors bind chemokines Interleukin-10 signaling
Drugs
Diseases
GWAS		Arthritis (juvenile idiopathic) ( 33106285) Basophil count ( 32888494) Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 32888494 27863252) Behcet's disease ( 33393726 23291587) Bone mineral density (Ward's triangle area) ( 27397699) Celiac disease ( 25920553 20190752 22057235 24999842 18311140) Celiac disease and Rheumatoid arthritis ( 26546613) Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Inflammatory bowel disease ( 26192919) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Monocyte chemoattractant protein-1 levels ( 23017229) Monocyte count ( 27863252 29403010) Narcolepsy with cataplexy ( 25986216) Obesity-related traits ( 23251661) Pancreatic beta-cell glucose sensitivity ( 32944759) Ulcerative colitis ( 26192919 28067908) White blood cell count (basophil) ( 27863252)	Blood protein levels ( 30072576) Body mass index ( 26426971)
Interacting Genes		19 interacting genes: CCL11 CCL13 CCL14 CCL15 CCL2 CCL24 CCL26 CCL28 CCL3 CCL3L1 CCL4 CCL5 CCL7 CCL8 CXCL10 CXCL11 CXCL9 FGR HCK	4 interacting genes: CCR1 CCR3 CCR5 DPP4
Entrez ID		1232	6349
HPRD ID		03167	03234
Ensembl ID		ENSG00000183625
Uniprot IDs		P51677 Q8TDP4 Q8TDP5	P16619
PDB IDs		7X9Y
Enriched GO Terms of Interacting Partners?		Chemokine Activity Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway CCR Chemokine Receptor Binding Antimicrobial Humoral Response Cell Chemotaxis Cytokine Activity Humoral Immune Response Chemotaxis Granulocyte Chemotaxis Locomotion Defense Response To Symbiont Inflammatory Response Defense Response To Other Organism Granulocyte Migration Eosinophil Chemotaxis Cytokine-mediated Signaling Pathway Leukocyte Chemotaxis Eosinophil Migration Leukocyte Migration Myeloid Leukocyte Migration Response To Other Organism Immune Response Cell Migration Response To External Biotic Stimulus Defense Response Cell Motility Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Locomotion Immune System Process Regulation Of Cell Migration Regulation Of Cell Motility Regulation Of Locomotion Extracellular Space Cell Surface Receptor Signaling Pathway Extracellular Region Response To Stress Regulation Of Lymphocyte Chemotaxis Cell-cell Signaling Signaling Cell Communication Regulation Of Leukocyte Migration Regulation Of Cell Shape Positive Regulation Of Leukocyte Migration Signal Transduction Positive Regulation Of Natural Killer Cell Chemotaxis Positive Regulation Of Calcium Ion Transport Intracellular Calcium Ion Homeostasis	Chemokine Receptor Activity C-C Chemokine Binding C-C Chemokine Receptor Activity Chemokine (C-C Motif) Ligand 5 Binding Chemotaxis Locomotion Chemokine-mediated Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Dendritic Cell Chemotaxis Cell Chemotaxis Cell Migration Dendritic Cell Migration Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity Cell Motility External Side Of Plasma Membrane Defense Response G Protein-coupled Receptor Activity Cellular Defense Response Cytokine-mediated Signaling Pathway Cellular Response To Cytokine Stimulus Response To Peptide Inflammatory Response Response To Cytokine Immune System Process Virus Receptor Activity Mononuclear Cell Migration Glucagon Processing Symbiont Entry Into Host Cell G Protein-coupled Receptor Signaling Pathway Leukocyte Chemotaxis Intracellular Signaling Cassette Cell Adhesion Chemokine (C-C Motif) Ligand 7 Binding Regulation Of Biological Quality Biological Process Involved In Interaction With Host Regulation Of Chemotaxis Regulation Of Leukocyte Migration Leukocyte Migration Response To Stress Negative Regulation Of Neutrophil Chemotaxis Psychomotor Behavior Calcium Ion Transport Immune Response Intercellular Canaliculus Negative Regulation Of Neutrophil Migration Negative Regulation Of Macrophage Apoptotic Process Receptor-mediated Virion Attachment To Host Cell Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Release Of Sequestered Calcium Ion Into Cytosol By Endoplasmic Reticulum
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