CEACAM8 and CEACAM1

Number of citations of the paper that reports this interaction (PMID 11994468)
24

Data Source:
HPRD (in vitro)

		CEACAM8	CEACAM1
Gene Name		carcinoembryonic antigen-related cell adhesion molecule 8	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Anchored Component Of Membrane Extracellular Vesicular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function		Molecular_function Protein Binding Protein Homodimerization Activity
	Biological Process	Immune Response Blood Coagulation Leukocyte Migration	Angiogenesis Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Integrin-mediated Signaling Pathway Blood Coagulation Cell Migration Leukocyte Migration
Pathways		Fibronectin matrix formation Cell surface interactions at the vascular wall	Fibronectin matrix formation Cell surface interactions at the vascular wall
Drugs			Arcitumomab Alpha-D-Mannose
Diseases
GWAS
Protein-Protein Interactions		2 interactors: CEACAM1 CEACAM6	18 interactors: ADRB2 ANXA2 CARTPT CD209 CEACAM3 CEACAM5 CEACAM6 CEACAM7 CEACAM8 EGFR FLNA INSR MAP3K10 PTPN11 PTPN6 PXN SHC1 SRC
Entrez ID		1088	634
HPRD ID		07630	00191
Ensembl ID		ENSG00000124469	ENSG00000079385
Uniprot IDs		B4DLI3 P31997 Q0Z7S6	P13688 Q3KRG8
PDB IDs		2DKS	2GK2
Enriched GO Terms of Interacting Partners?		Leukocyte Migration Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Response To Wounding Cell Migration Cell Motility Locomotion Movement Of Cell Or Subcellular Component Immune System Process Integrin-mediated Signaling Pathway Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Response To Stress	Activation Of Protein Kinase Activity Positive Regulation Of Intracellular Signal Transduction Regulation Of MAPK Cascade Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Phosphorylation Positive Regulation Of Protein Kinase Activity Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Regulation Of MAP Kinase Activity Positive Regulation Of Kinase Activity Regulation Of Kinase Activity Positive Regulation Of Transferase Activity Positive Regulation Of Phosphorylation Positive Regulation Of Signal Transduction Positive Regulation Of Protein Modification Process Regulation Of Phosphorylation Positive Regulation Of MAP Kinase Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Intracellular Signal Transduction Regulation Of Body Fluid Levels Regulation Of Cellular Protein Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Stress Leukocyte Migration Blood Coagulation Hemostasis Cellular Response To Organonitrogen Compound Peptidyl-tyrosine Phosphorylation Single Organismal Cell-cell Adhesion Regulation Of Catalytic Activity Activation Of MAPK Activity Cellular Response To Peptide Hormone Stimulus Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Peptide Cellular Response To Hormone Stimulus Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Wound Healing Regulation Of Signal Transduction Positive Regulation Of Catalytic Activity Response To Wounding Positive Regulation Of Transport Response To Peptide Hormone Cell Adhesion Regulation Of Signaling Abortive Mitotic Cell Cycle
Tagcloud ?			4l adhesion carcinoembryonic chemotactic clinicopathologic cxcl density explore extent immunohistochemistry infiltration ln lymph metastasis microarray neutrophil neutrophils node overexpression peritumoral poorer probe qrt squamous tissues tongue tscc upregulate upregulating
Tagcloud (Difference) ?			4l adhesion carcinoembryonic chemotactic clinicopathologic cxcl density explore extent immunohistochemistry infiltration ln lymph metastasis microarray neutrophil neutrophils node overexpression peritumoral poorer probe qrt squamous tissues tongue tscc upregulate upregulating
Tagcloud (Intersection) ?