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RPS27A and PTEN
Number of citations of the paper that reports this interaction (PubMedID
30631154
)
76
Data Source:
BioGRID
(pull down, affinity chromatography technology)
RPS27A
PTEN
Description
ribosomal protein S27a
phosphatase and tensin homolog
Image
GO Annotations
Cellular Component
Extracellular Space
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Mitochondrial Outer Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Cytosol
Ribosome
Plasma Membrane
Endosome Membrane
Small Ribosomal Subunit
Membrane
Cytosolic Ribosome
Cytosolic Small Ribosomal Subunit
Endocytic Vesicle Membrane
Vesicle
Small-subunit Processome
Synapse
Extracellular Exosome
Ribonucleoprotein Complex
Extracellular Region
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Plasma Membrane
Cytoplasmic Side Of Plasma Membrane
Postsynaptic Density
Apical Plasma Membrane
PML Body
Myelin Sheath Adaxonal Region
Cell Projection
Neuron Projection
Dendritic Spine
Schmidt-Lanterman Incisure
Synapse
Molecular Function
RNA Binding
Structural Constituent Of Ribosome
Protein Binding
Zinc Ion Binding
Protein Tag Activity
Ubiquitin Protein Ligase Binding
Metal Ion Binding
Phosphatidylinositol-3-phosphate Phosphatase Activity
Phosphoprotein Phosphatase Activity
Protein Serine/threonine Phosphatase Activity
Protein Tyrosine Phosphatase Activity
Protein Binding
Beta-catenin Binding
Lipid Binding
Anaphase-promoting Complex Binding
Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity
Hydrolase Activity
Phosphatase Activity
Enzyme Binding
PDZ Domain Binding
Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity
Identical Protein Binding
Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity
Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity
Phosphatidylinositol Phosphate Phosphatase Activity
Molecular Function Inhibitor Activity
Ubiquitin-specific Protease Binding
Ubiquitin Ligase Activator Activity
Biological Process
Cytoplasmic Translation
Translation
Protein Ubiquitination
Modification-dependent Protein Catabolic Process
Ribosomal Small Subunit Biogenesis
Osteoblast Differentiation
Protein Dephosphorylation
Lipid Metabolic Process
Phosphatidylinositol Biosynthetic Process
Apoptotic Process
Spindle Assembly Involved In Female Meiosis
Neuron-neuron Synaptic Transmission
Nervous System Development
Synapse Assembly
Central Nervous System Development
Heart Development
Learning Or Memory
Locomotory Behavior
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Cell Population Proliferation
Regulation Of Signal Transduction
Positive Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Cell Communication
Negative Regulation Of Epithelial To Mesenchymal Transition
Regulation Of Neuron Projection Development
Negative Regulation Of Neuron Projection Development
Cell Migration
Dentate Gyrus Development
Central Nervous System Neuron Axonogenesis
Negative Regulation Of Signaling
Negative Regulation Of Cell Migration
Adult Behavior
Regulation Of Protein Stability
Central Nervous System Myelin Maintenance
Negative Regulation Of Peptidyl-serine Phosphorylation
Multicellular Organismal Response To Stress
Social Behavior
Maternal Behavior
Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Locomotor Rhythm
Regulation Of Cell Differentiation
Negative Regulation Of Osteoblast Differentiation
Negative Regulation Of Cell Size
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Organ Growth
Phosphatidylinositol Dephosphorylation
Forebrain Morphogenesis
Cell Motility
Negative Regulation Of Axonogenesis
Protein Stabilization
Negative Regulation Of Developmental Process
Negative Regulation Of Cellular Component Organization
Negative Regulation Of Multicellular Organismal Process
Negative Regulation Of Keratinocyte Migration
Regulation Of Cell Cycle
Negative Regulation Of Focal Adhesion Assembly
Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Rhythmic Synaptic Transmission
Synapse Maturation
Prepulse Inhibition
Dendritic Spine Morphogenesis
Regulation Of Biological Quality
Cellular Response To Electrical Stimulus
Negative Regulation Of Excitatory Postsynaptic Potential
Presynaptic Membrane Assembly
Postsynaptic Density Assembly
Positive Regulation Of Intracellular Signal Transduction
Negative Regulation Of Cell Cycle G1/S Phase Transition
Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells
Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Excitatory Postsynaptic Potential
Negative Regulation Of Cellular Senescence
Negative Regulation Of Synaptic Vesicle Clustering
Pathways
Translesion synthesis by REV1
Recognition of DNA damage by PCNA-containing replication complex
Translesion Synthesis by POLH
Activation of NF-kappaB in B cells
ISG15 antiviral mechanism
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants
ER-Phagosome pathway
Downregulation of ERBB4 signaling
Spry regulation of FGF signaling
Downregulation of ERBB2:ERBB3 signaling
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
Budding and maturation of HIV virion
NOD1/2 Signaling Pathway
TICAM1, RIP1-mediated IKK complex recruitment
DDX58/IFIH1-mediated induction of interferon-alpha/beta
APC/C:Cdc20 mediated degradation of Cyclin B
Autodegradation of Cdh1 by Cdh1:APC/C
SCF-beta-TrCP mediated degradation of Emi1
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Membrane binding and targetting of GAG proteins
Assembly Of The HIV Virion
APC-Cdc20 mediated degradation of Nek2A
SRP-dependent cotranslational protein targeting to membrane
SRP-dependent cotranslational protein targeting to membrane
Vpu mediated degradation of CD4
Vif-mediated degradation of APOBEC3G
EGFR downregulation
SCF(Skp2)-mediated degradation of p27/p21
Viral mRNA Translation
Degradation of beta-catenin by the destruction complex
TCF dependent signaling in response to WNT
Downstream TCR signaling
NRIF signals cell death from the nucleus
p75NTR recruits signalling complexes
NF-kB is activated and signals survival
Regulation of activated PAK-2p34 by proteasome mediated degradation
NOTCH1 Intracellular Domain Regulates Transcription
Activated NOTCH1 Transmits Signal to the Nucleus
Activated NOTCH1 Transmits Signal to the Nucleus
Downregulation of TGF-beta receptor signaling
Downregulation of TGF-beta receptor signaling
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
Downregulation of SMAD2/3:SMAD4 transcriptional activity
Downregulation of SMAD2/3:SMAD4 transcriptional activity
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Selenocysteine synthesis
Separation of Sister Chromatids
Oxidative Stress Induced Senescence
Senescence-Associated Secretory Phenotype (SASP)
Oncogene Induced Senescence
Regulation of PLK1 Activity at G2/M Transition
Constitutive Signaling by NOTCH1 PEST Domain Mutants
Stimuli-sensing channels
Constitutive Signaling by NOTCH1 HD Domain Mutants
FCERI mediated NF-kB activation
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
NOTCH2 Activation and Transmission of Signal to the Nucleus
Regulation of innate immune responses to cytosolic DNA
Glycogen synthesis
Autodegradation of the E3 ubiquitin ligase COP1
Deactivation of the beta-catenin transactivating complex
Myoclonic epilepsy of Lafora
ABC-family proteins mediated transport
TAK1-dependent IKK and NF-kappa-B activation
activated TAK1 mediates p38 MAPK activation
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
AUF1 (hnRNP D0) binds and destabilizes mRNA
Asymmetric localization of PCP proteins
Degradation of AXIN
Degradation of DVL
Regulation of FZD by ubiquitination
PINK1-PRKN Mediated Mitophagy
N-glycan trimming in the ER and Calnexin/Calreticulin cycle
Regulation of TNFR1 signaling
TNFR1-induced NF-kappa-B signaling pathway
Hedgehog ligand biogenesis
Hh mutants are degraded by ERAD
Dectin-1 mediated noncanonical NF-kB signaling
CLEC7A (Dectin-1) signaling
Degradation of GLI1 by the proteasome
Degradation of GLI2 by the proteasome
GLI3 is processed to GLI3R by the proteasome
Hedgehog 'on' state
Hedgehog 'on' state
Negative regulation of FGFR1 signaling
Negative regulation of FGFR2 signaling
Negative regulation of FGFR3 signaling
Negative regulation of FGFR4 signaling
Translesion synthesis by POLK
Translesion synthesis by POLI
Termination of translesion DNA synthesis
Regulation of RAS by GAPs
TNFR2 non-canonical NF-kB pathway
Negative regulation of MAPK pathway
Regulation of necroptotic cell death
NIK-->noncanonical NF-kB signaling
Defective CFTR causes cystic fibrosis
MAP3K8 (TPL2)-dependent MAPK1/3 activation
HDR through Homologous Recombination (HRR)
MAPK6/MAPK4 signaling
UCH proteinases
UCH proteinases
Josephin domain DUBs
Ub-specific processing proteases
Ovarian tumor domain proteases
Metalloprotease DUBs
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Processing of DNA double-strand break ends
DNA Damage Recognition in GG-NER
Formation of Incision Complex in GG-NER
Gap-filling DNA repair synthesis and ligation in GG-NER
Dual Incision in GG-NER
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
Fanconi Anemia Pathway
Major pathway of rRNA processing in the nucleolus and cytosol
Regulation of TP53 Activity through Phosphorylation
Regulation of TP53 Degradation
Regulation of TP53 Activity through Methylation
Negative regulation of MET activity
Assembly of the pre-replicative complex
Orc1 removal from chromatin
CDK-mediated phosphorylation and removal of Cdc6
Cyclin D associated events in G1
G2/M Checkpoints
Stabilization of p53
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Ubiquitin-dependent degradation of Cyclin D
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1
The role of GTSE1 in G2/M progression after G2 checkpoint
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
Downregulation of ERBB2 signaling
VLDLR internalisation and degradation
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
E3 ubiquitin ligases ubiquitinate target proteins
InlB-mediated entry of Listeria monocytogenes into host cell
InlB-mediated entry of Listeria monocytogenes into host cell
InlA-mediated entry of Listeria monocytogenes into host cells
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Regulation of RUNX2 expression and activity
Regulation of RUNX2 expression and activity
Regulation of RUNX3 expression and activity
Regulation of PTEN localization
Regulation of PTEN stability and activity
Neddylation
ER Quality Control Compartment (ERQC)
Regulation of expression of SLITs and ROBOs
Regulation of expression of SLITs and ROBOs
NOTCH3 Activation and Transmission of Signal to the Nucleus
NOTCH3 Activation and Transmission of Signal to the Nucleus
TICAM1-dependent activation of IRF3/IRF7
TICAM1,TRAF6-dependent induction of TAK1 complex
Interleukin-1 signaling
Peroxisomal protein import
Peroxisomal protein import
Interferon alpha/beta signaling
Regulation of signaling by CBL
Endosomal Sorting Complex Required For Transport (ESCRT)
Iron uptake and transport
Negative regulators of DDX58/IFIH1 signaling
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE)
IRAK1 recruits IKK complex
IKK complex recruitment mediated by RIP1
IRAK2 mediated activation of TAK1 complex
TRAF6-mediated induction of TAK1 complex within TLR4 complex
Negative regulation of NOTCH4 signaling
Chaperone Mediated Autophagy
Late endosomal microautophagy
Response of EIF2AK4 (GCN2) to amino acid deficiency
Prevention of phagosomal-lysosomal fusion
Modulation by Mtb of host immune system
Alpha-protein kinase 1 signaling pathway
Aggrephagy
Aggrephagy
RAS processing
Pexophagy
Signaling by CSF1 (M-CSF) in myeloid cells
Maturation of protein E
SARS-CoV-1 activates/modulates innate immune responses
Maturation of protein E
Inactivation of CSF3 (G-CSF) signaling
SARS-CoV-2 activates/modulates innate and adaptive immune responses
Negative regulation of FLT3
FLT3 signaling by CBL mutants
Regulation of BACH1 activity
Signaling by ALK fusions and activated point mutants
SARS-CoV-1 modulates host translation machinery
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
SARS-CoV-2 modulates host translation machinery
KEAP1-NFE2L2 pathway
Regulation of NF-kappa B signaling
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2
Degradation of CDH1
Amyloid fiber formation
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation
Antigen processing: Ubiquitination & Proteasome degradation
Evasion by RSV of host interferon responses
Regulation of pyruvate metabolism
GSK3B-mediated proteasomal degradation of PD-L1(CD274)
SPOP-mediated proteasomal degradation of PD-L1(CD274)
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)
PD-L1(CD274) glycosylation and translocation to plasma membrane
Degradation of CRY and PER proteins
Degradation of CRY and PER proteins
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Synthesis of PIPs at the plasma membrane
Synthesis of IP3 and IP4 in the cytosol
Negative regulation of the PI3K/AKT network
Downstream TCR signaling
TP53 Regulates Metabolic Genes
PTEN Loss of Function in Cancer
Ub-specific processing proteases
Ovarian tumor domain proteases
Regulation of PTEN mRNA translation
Regulation of PTEN localization
Regulation of PTEN stability and activity
Transcriptional Regulation by MECP2
Drugs
Phosphatidylethanolamine
Diseases
Vulvar cancer
Breast cancer
Malignant melanoma
Prostate cancer
Hepatocellular carcinoma
Small cell lung cancer
Endometrial Cancer
Glioma
GWAS
Alanine aminotransferase levels (
33547301
)
Ambidextrousness (
32989287
)
Birth weight (
31043758
)
Eosinophil count (
27863252
32888494
)
Eosinophil percentage of granulocytes (
27863252
)
Eosinophil percentage of white cells (
32888494
27863252
)
Fasting insulin (
34059833
)
Height (
31562340
)
Liver enzyme levels (alanine transaminase) (
33972514
)
Lymphocyte percentage of white cells (
32888494
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Mercury levels (
26025379
)
Multiple sclerosis (
31604244
)
Neutrophil count (
32888494
)
Neutrophil percentage of granulocytes (
27863252
)
Neutrophil percentage of white cells (
32888494
)
Periodontitis (Mean PAL) (
24024966
)
Platelet count (
32888494
)
Plateletcrit (
32888494
)
Psoriasis (
28537254
)
Pulse pressure (
27841878
)
Red blood cell count (
32888494
)
Sum eosinophil basophil counts (
27863252
)
Systolic blood pressure and diastolic blood pressure (bivariate analysis) (
33539483
)
Thyroid stimulating hormone levels (
32769997
30367059
)
Type 2 diabetes (
32499647
24509480
)
Type 2 diabetes (adjusted for BMI) (
30297969
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
White blood cell count (
32888494
)
White blood cell count (basophil) (
29403010
)
Interacting Genes
41 interacting genes:
ACVR1
APP
BACH1
BMPR1B
CALCOCO2
CDC6
CDK11B
DAZAP2
DESI1
DNAJB2
EPN2
EPN3
FAM168A
FOXP1
FSHR
GGA1
GGA3
KANSL3
LITAF
MAST2
MTURN
PAXIP1
PLEKHB2
PLSCR4
POLH
PTEN
RABGEF1
RAD23A
RBPMS
RNF11
RNF26
SMAD1
SMAD2
SMAD4
SMURF1
SMURF2
TGFBR1
TRAF6
UBQLN1
WBP2
ZNF512B
376 interacting genes:
AATK
ABCF2
ACTL6A
ADAR
AFP
AKAP12
AKT1
ALYREF
AMOT
ANAPC10
ANAPC7
ANG
ANP32B
ANP32E
ANXA2
AR
ARF4
ARMCX3
ASCC3
ATM
ATP5F1A
ATP5F1C
BCAR1
BEX1
BGLT3
BUB3
CACTIN-AS1
CAD
CALM1
CAMK2G
CAV1
CBL
CCDC180
CCDC47
CCND2
CCT2
CCT3
CCT4
CCT6A
CCT8
CDC27
CEP170
CEP97
CFL1
CHD4
CHGB
CMAS
COPA
COPB1
COPS6
CREB1
CSNK1A1
CSNK2A1
CSNK2A2
CUL4B
CXCL1
CXXC1
DAP3
DAXX
DBN1
DCAF11
DCAF13
DDB1
DDOST
DDX1
DDX21
DDX24
DDX47
DDX50
DHX15
DHX9
DLC1
DLG1
DNAJA1
DNAJA2
DNAJA3
DNAJB6
DNAJC10
DPM1
DRG1
DSP
EEF2
EIF4E
EIF6
EML1
EPHA2
EPRS1
ERBB3
ESR1
EXOSC1
EXOSC2
EXOSC4
EXOSC5
EXOSC7
FARSA
FARSB
FASN
FBL
FBXW11
FLNA
FOXK1
FUBP3
GEMIN4
GNAI1
GNAI2
GNB4
GNL3
GPC4
GSTM2
GTF3C2
GTF3C3
GTF3C5
H2AC4
H2AX
HADHA
HBA1
HNRNPA1
HNRNPA3
HNRNPAB
HNRNPUL1
HSD17B1
HSD17B10
HSP90B1
HSPA4
HSPA4L
HSPA8
HSPBP1
HSPD1
HSPH1
IL24
ILF2
ILF3
INS
IPO5
IPO7
IRS4
ITPRID2
JUP
KBTBD4
KDM1A
KPNB1
LATS1
LGALS1
LIMA1
LINC00839
LINC01198
LINC02023
LMNB1
LRPPRC
LTV1
MAGED2
MAGI2
MAGI3
MAP2K3
MAST1
MAST2
MAST3
MATR3
MCM2
MCM3
MCM5
MCRS1
MDC1
MDN1
METTL26
MEX3C
MKI67
MME
MPRIP
MRPS22
MRPS23
MRPS27
MRPS28
MRPS7
MRPS9
MSH6
MTHFD2
MVP
MYBBP1A
MYC
MYH10
MYL12A
MYO1B
MYO1C
MYO1D
MYOF
NACA
NCBP1
NCF1
NDFIP1
NEDD4
NGB
NHERF1
NHERF2
NOP56
NOP58
NPM3
NUMB
OSGIN1
PBK
PBRM1
PCNA
PDGFRB
PELO
PELP1
PHB1
PHB2
PICK1
PIK3R1
PKM
PLEC
PLK1
POLDIP2
POLR1A
POLR2A
POLR2B
POLR2H
POP1
PPL
PPP1CA
PPP2CA
PRDX1
PRDX3
PRKDC
PRPF19
PRPF8
PSMD3
PSMD4
PSMD7
PTDSS1
PTK7
PURA
PXN
QPCTL
RAD21
RANBP2
RANGAP1
RBBP5
RBM4
RCC2
RCN1
RFC3
RFC4
RFC5
RING1
RNF31
RPL10
RPL10A
RPL12
RPL13
RPL13A
RPL14
RPL17
RPL18A
RPL21
RPL22
RPL22L1
RPL23
RPL23A
RPL27
RPL27A
RPL28
RPL30
RPL31
RPL32
RPL34
RPL36
RPL38
RPL7
RPLP0
RPLP2
RPN2
RPP30
RPP38
RPP40
RPS11
RPS13
RPS15
RPS15A
RPS17
RPS2
RPS20
RPS23
RPS25
RPS26
RPS27
RPS27A
RPS3
RPS4X
RPS5
RPS6
RPS9
RSL1D1
RYBP
S100A8
S100A9
SDC1
SDC4
SDCBP
SEC61A1
SET
SETX
SHARPIN
SHROOM3
SIN3A
SIRT4
SKP1
SLC25A1
SLC25A13
SLC25A3
SLC25A5
SMARCA4
SMARCA5
SMC2
SMC4
SMCHD1
SMURF1
SNAI1
SNRNP200
SNRPA1
SNRPB2
SNRPD1
SNTB2
SNX27
SPOP
SPTAN1
SPTBN1
SRP14
SSB
SSR4
SSRP1
STAG2
STK11
STRAP
SUDS3
SUGP2
TCF25
TCP1
TECR
TERF2IP
THOC2
THOC3
THOC6
TMEFF1
TNKS
TNKS2
TNPO3
TP53
TP53BP1
TRIM25
TRIM28
TRMO
TUBA1B
TUBB
TUBB4B
TUFM
TWIST1
TXN
U2AF1
UBE2I
UBE2L3
UPF1
USP7
USP9X
UTP14A
UTRN
WWP1
WWP2
XRCC5
XRCC6
YAF2
YAP1
YES1
YTHDC2
YTHDF2
ZNF326
Entrez ID
6233
5728
HPRD ID
01878
03431
Ensembl ID
ENSG00000143947
ENSG00000171862
Uniprot IDs
B2RDW1
P62979
F6KD01
P60484
PDB IDs
2KHW
2KOX
2KTF
2KWU
2KWV
2L0F
2L0T
2XK5
3AXC
3I3T
3K9P
3N30
3N32
3NHE
3NOB
3NS8
3PHD
3PHW
3TBL
3VDZ
4R62
4UG0
4V6X
5A2Q
5AJ0
5FLX
5LKS
5T2C
5WVO
5YDK
6DC6
6FEC
6G18
6G51
6G53
6G5H
6G5I
6IP5
6IP6
6IP8
6J99
6KFP
6KG6
6KIU
6KIV
6KIW
6OLE
6OLF
6OLG
6OLI
6OLZ
6OM0
6OM7
6QZP
6SQO
6SQR
6SQS
6XA1
6Y0G
6Y57
6YBS
6Z6L
6Z6M
6Z6N
6ZLW
6ZM7
6ZME
6ZMI
6ZMO
6ZMT
6ZMW
6ZN5
6ZOJ
6ZOL
6ZON
6ZP4
6ZUO
6ZV6
6ZVH
6ZVJ
6ZXD
6ZXE
6ZXF
6ZXG
6ZXH
7A09
7BWD
7F0N
7JQB
7JQC
7K5I
7MQ9
7MQA
7OOJ
7QP6
7QP7
7R4X
7TQL
7WTT
7WTU
7WTV
7WTW
7WTX
7WTZ
7WU0
7XNY
8G5Y
8G60
8G61
8G6J
8GLP
8HTC
8HTF
8IFD
8IFE
8IVB
8K2C
8OZ0
8PJ1
8PJ2
8PJ3
8PJ4
8PJ5
8PJ6
8PPK
8PPL
8QOI
8T4S
8UKB
8X7I
8X7J
8XP2
8XP3
8XSX
8XSY
8XSZ
8XXL
8XXM
8XXN
8YOO
8YOP
8ZDB
8ZDC
8ZDD
9BKD
9BLN
9C3H
9G8M
9G8O
9IJU
9IML
9IPU
1D5R
2KYL
4O1V
5BUG
5BZX
5BZZ
7JTX
7JUK
7JUL
7JVX
7PC7
8X3S
Enriched GO Terms of Interacting Partners
?
Regulation Of Metabolic Process
Regulation Of Macromolecule Metabolic Process
SMAD Binding
Regulation Of Primary Metabolic Process
I-SMAD Binding
Positive Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Metabolic Process
Transforming Growth Factor Beta Receptor Activity, Type I
Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway
Protein Serine/threonine Kinase Binding
Regulation Of Nucleobase-containing Compound Metabolic Process
Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
SMAD Protein Signal Transduction
SMAD Protein Complex
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Heteromeric SMAD Protein Complex
Activin Receptor Signaling Pathway
Endosome
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Protein-containing Complex
BMP Signaling Pathway
Endothelial Cell Activation
Regulation Of DNA-templated Transcription
Positive Regulation Of RNA Metabolic Process
Positive Regulation Of Signal Transduction
Regulation Of RNA Biosynthetic Process
Regulation Of Protein Catabolic Process
Transmembrane Receptor Protein Serine/threonine Kinase Activity
Regulation Of Multicellular Organismal Process
Positive Regulation Of Transcription By RNA Polymerase II
Transforming Growth Factor Beta Receptor Signaling Pathway
Positive Regulation Of Catabolic Process
Homomeric SMAD Protein Complex
Regulation Of Protein Metabolic Process
Regulation Of Epithelial To Mesenchymal Transition
Positive Regulation Of Cell Communication
Regulation Of RNA Metabolic Process
Positive Regulation Of Signaling
Regulation Of Cell Differentiation
Positive Regulation Of Proteolysis
Response To Growth Factor
Positive Regulation Of Protein Catabolic Process
Positive Regulation Of Epithelial To Mesenchymal Transition
Negative Regulation Of Signal Transduction
Osteoblast Differentiation
Positive Regulation Of Protein Metabolic Process
Activin Responsive Factor Complex
Regulation Of Developmental Process
Positive Regulation Of Proteolysis Involved In Protein Catabolic Process
RNA Binding
Ribonucleoprotein Complex
Cytosolic Ribosome
Cytoplasmic Translation
Structural Constituent Of Ribosome
Ribosome
Macromolecule Metabolic Process
Translation
Nucleolus
Nucleoplasm
Nucleic Acid Metabolic Process
Macromolecule Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Cytosol
Nucleus
Cytosolic Large Ribosomal Subunit
Cytoplasm
RNA Metabolic Process
Extracellular Exosome
Focal Adhesion
RRNA Metabolic Process
Protein Metabolic Process
Cytosolic Small Ribosomal Subunit
Ribonucleoprotein Complex Biogenesis
RNA Processing
Regulation Of DNA Metabolic Process
Protein Binding
Small Ribosomal Subunit
ATP Binding
Chromosome, Telomeric Region
ATP Hydrolysis Activity
Small-subunit Processome
Positive Regulation Of DNA Biosynthetic Process
RRNA Processing
Positive Regulation Of DNA Metabolic Process
Regulation Of Chromosome Organization
Ribosomal Small Subunit Biogenesis
MRNA Metabolic Process
Nucleotide Binding
DNA Metabolic Process
Protein Localization To Organelle
Nucleocytoplasmic Transport
Nuclear Transport
Regulation Of Telomere Maintenance
Positive Regulation Of Protein Localization To Nucleus
ATP-dependent Protein Folding Chaperone
Positive Regulation Of Chromosome Organization
Positive Regulation Of Telomere Maintenance Via Telomerase
Chromosome
Cadherin Binding
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