RPS23 and OGFOD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RPS23	OGFOD1
Description		ribosomal protein S23	2-oxoglutarate and iron dependent oxygenase domain containing 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Rough Endoplasmic Reticulum Cytosol Ribosome Small Ribosomal Subunit Membrane Cytosolic Ribosome Cytosolic Small Ribosomal Subunit Small-subunit Processome Synapse Ribonucleoprotein Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoplasmic Stress Granule
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	Iron Ion Binding Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen 2-oxoglutarate-dependent Dioxygenase Activity L-ascorbic Acid Binding Peptidyl-proline Dioxygenase Activity Peptidyl-proline 3-dioxygenase Activity Metal Ion Binding Dioxygenase Activity
	Biological Process	Cytoplasmic Translation Translation Stress Granule Assembly Ribosomal Small Subunit Biogenesis Maintenance Of Translational Fidelity	Regulation Of Translational Termination Cell Population Proliferation Protein Hydroxylation Peptidyl-proline Hydroxylation Stress Granule Assembly
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Protein hydroxylation Response of EIF2AK4 (GCN2) to amino acid deficiency SARS-CoV-1 modulates host translation machinery SARS-CoV-2 modulates host translation machinery Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA	Protein hydroxylation
Drugs			Ascorbic acid
Diseases
GWAS		Carotid intima media thickness (mean) ( 31801372)
Interacting Genes		5 interacting genes: DARS1-AS1 MDM2 OGFOD1 PTEN UBC	3 interacting genes: FEM1A LIG4 RPS23
Entrez ID		6228	55239
HPRD ID		04729	08553
Ensembl ID		ENSG00000186468	ENSG00000087263
Uniprot IDs		A8K517 P62266	Q8N543
PDB IDs		4CXG 4CXH 4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBW 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOK 6ZON 6ZP4 6ZUO 6ZV6 6ZVH 6ZVJ 6ZXD 6ZXE 6ZXF 6ZXG 6ZXH 7A09 7K5I 7MQ8 7MQ9 7MQA 7QP6 7QP7 7R4X 7TQL 7WTS 7WTT 7WTU 7WTV 7WTW 7WTX 7WTZ 7WU0 7XNX 7XNY 8IFD 8IFE 8JDJ 8JDK 8JDL 8JDM 8K2C 8OZ0 8PJ1 8PJ2 8PJ3 8PJ4 8PJ5 8PJ6 8PPK 8QOI 8T4S 8UKB 8XP2 8XP3 8XSX 8XSY 8XSZ 8XXL 8XXM 8XXN 8Y0W 8Y0X 8YOO 8YOP 8ZDB 8ZDC 8ZDD 9BKD 9BLN 9C3H 9G8M 9G8O	4NHX 4NHY
Enriched GO Terms of Interacting Partners?		Protein Modification Process Response To Vitamin B1 NEDD8 Ligase Activity Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Response To Actinomycin D Regulation Of G1/S Transition Of Mitotic Cell Cycle Endocytic Vesicle Membrane Regulation Of Ubiquitin-dependent Protein Catabolic Process Response To Water-immersion Restraint Stress Response To Formaldehyde Cellular Response To Vitamin B1 Regulation Of Smooth Muscle Cell Proliferation Traversing Start Control Point Of Mitotic Cell Cycle Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Cellular Response To Actinomycin D Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Negative Regulation Of Neuron Projection Development Negative Regulation Of Cell Projection Organization Negative Regulation Of Synaptic Vesicle Clustering Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Peptidyl-proline 3-dioxygenase Activity Peptidyl-proline Dioxygenase Activity Peptidyl-proline Hydroxylation Positive Regulation Of Proteolysis Cellular Response To UV-C Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Phosphatidylinositol Phosphate Phosphatase Activity Receptor Serine/threonine Kinase Binding Regulation Of Synaptic Vesicle Clustering Postsynaptic Density Atrial Septum Development Fibroblast Activation Heart Development Negative Regulation Of Peptidyl-serine Phosphorylation Neuron-neuron Synaptic Transmission Negative Regulation Of Cell Size Anaphase-promoting Complex Binding Postsynaptic Density Assembly Forebrain Morphogenesis Presynaptic Membrane Assembly Membraneless Organelle Assembly	Establishment Of Integrated Proviral Latency DNA Ligase (ATP) Activity DNA Ligase IV Complex Pro-B Cell Differentiation T Cell Receptor V(D)J Recombination Establishment Of Viral Latency DNA Ligase Activity DN2 Thymocyte Differentiation Maintenance Of Translational Fidelity EP4 Subtype Prostaglandin E2 Receptor Binding Nucleotide-excision Repair, DNA Gap Filling DNA-dependent Protein Kinase-DNA Ligase 4 Complex Immunoglobulin V(D)J Recombination Nonhomologous End Joining Complex Double-strand Break Repair Via Classical Nonhomologous End Joining Lymphoid Progenitor Cell Differentiation Single Strand Break Repair AMP Binding Ubiquitin-dependent Protein Catabolic Process Via The C-end Degron Rule Pathway Cellular Response To Lithium Ion Response To Lithium Ion Cul2-RING Ubiquitin Ligase Complex V(D)J Recombination Isotype Switching Somatic Recombination Of Immunoglobulin Genes Involved In Immune Response Small Ribosomal Subunit Regulation Of Ubiquitin-protein Transferase Activity Response To X-ray Somatic Diversification Of Immunoglobulins Involved In Immune Response Somatic Recombination Of Immunoglobulin Gene Segments Condensed Chromosome Base-excision Repair Stress Granule Assembly Rough Endoplasmic Reticulum Cytosolic Small Ribosomal Subunit Somatic Cell DNA Recombination T Cell Differentiation In Thymus Somatic Diversification Of Immunoglobulins Fibroblast Proliferation
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