RPS23

Gene Name		ribosomal protein S23
Image
Gene Ontology Annotations	Cellular Component	Nucleolus Cytoplasm Cytosol Ribosome Membrane Cytosolic Small Ribosomal Subunit
	Molecular Function	Structural Constituent Of Ribosome Protein Binding Poly(A) RNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways		Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: MDM2
Entrez ID		6228
HPRD ID		04729
Ensembl ID		ENSG00000186468
Uniprot IDs		A8K517 P62266
PDB IDs		3J3A
Enriched GO Terms of Interacting Partners?		Cellular Response To UV-C Cellular Response To Vitamin B1 Traversing Start Control Point Of Mitotic Cell Cycle Response To Vitamin B1 Response To Ether Response To UV-C Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Protein Export From Nucleus Response To Magnesium Ion Negative Regulation Of Cell Cycle Arrest Cellular Response To Antibiotic Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Cellular Response To Toxic Substance Negative Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Cell Cycle G1/S Phase Transition Protein Destabilization Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Cellular Response To Estrogen Stimulus Regulation Of Protein Export From Nucleus Response To Iron Ion Cellular Response To Alkaloid Response To Morphine Cellular Response To Nutrient Regulation Of Signal Transduction By P53 Class Mediator Response To Cocaine Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Response To Antibiotic Cellular Response To Hydrogen Peroxide Cellular Response To UV Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Arrest DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Signal Transduction In Response To DNA Damage Cellular Response To Light Stimulus Response To Ammonium Ion Regulation Of Cell Cycle Arrest Mitotic DNA Damage Checkpoint Cellular Response To Hypoxia
Tagcloud ?		3p applications biogenesis contained define downregulating library mdm2 mechanistically mimics mir mirna mirnas modulate network p53 regulator ribosomal ribosome rpl11 screen stability stabilization subset throughput transcript untranslated upregulation weakening