OGFOD1 and FEM1A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		OGFOD1	FEM1A
Description		2-oxoglutarate and iron dependent oxygenase domain containing 1	fem-1 homolog A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoplasmic Stress Granule	Ubiquitin Ligase Complex Cytoplasm Mitochondrion Cytosol Cul2-RING Ubiquitin Ligase Complex
	Molecular Function	Iron Ion Binding Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen 2-oxoglutarate-dependent Dioxygenase Activity L-ascorbic Acid Binding Peptidyl-proline Dioxygenase Activity Peptidyl-proline 3-dioxygenase Activity Metal Ion Binding Dioxygenase Activity	Protein Binding EP4 Subtype Prostaglandin E2 Receptor Binding Molecular Adaptor Activity Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Regulation Of Translational Termination Cell Population Proliferation Protein Hydroxylation Peptidyl-proline Hydroxylation Stress Granule Assembly	MAPK Cascade Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Inflammatory Response Positive Regulation Of Inflammatory Response Regulation Of Ubiquitin-protein Transferase Activity Ubiquitin-dependent Protein Catabolic Process Via The C-end Degron Rule Pathway
Pathways		Protein hydroxylation	Neddylation
Drugs		Ascorbic acid
Diseases
GWAS			Height ( 31562340)
Interacting Genes		3 interacting genes: FEM1A LIG4 RPS23	11 interacting genes: ACAA1 GOLGA6L9 INCA1 KIFC3 MALT1 MYOM3 NDUFAB1 OGFOD1 PPM1F PTGER4 WWOX
Entrez ID		55239	55527
HPRD ID		08553	16888
Ensembl ID		ENSG00000087263	ENSG00000141965
Uniprot IDs		Q8N543	Q9BSK4
PDB IDs		4NHX 4NHY
Enriched GO Terms of Interacting Partners?		Establishment Of Integrated Proviral Latency DNA Ligase (ATP) Activity DNA Ligase IV Complex Pro-B Cell Differentiation T Cell Receptor V(D)J Recombination Establishment Of Viral Latency DNA Ligase Activity DN2 Thymocyte Differentiation Maintenance Of Translational Fidelity EP4 Subtype Prostaglandin E2 Receptor Binding Nucleotide-excision Repair, DNA Gap Filling DNA-dependent Protein Kinase-DNA Ligase 4 Complex Immunoglobulin V(D)J Recombination Nonhomologous End Joining Complex Double-strand Break Repair Via Classical Nonhomologous End Joining Lymphoid Progenitor Cell Differentiation Single Strand Break Repair AMP Binding Ubiquitin-dependent Protein Catabolic Process Via The C-end Degron Rule Pathway Cellular Response To Lithium Ion Response To Lithium Ion Cul2-RING Ubiquitin Ligase Complex V(D)J Recombination Isotype Switching Somatic Recombination Of Immunoglobulin Genes Involved In Immune Response Small Ribosomal Subunit Regulation Of Ubiquitin-protein Transferase Activity Response To X-ray Somatic Diversification Of Immunoglobulins Involved In Immune Response Somatic Recombination Of Immunoglobulin Gene Segments Condensed Chromosome Base-excision Repair Stress Granule Assembly Rough Endoplasmic Reticulum Cytosolic Small Ribosomal Subunit Somatic Cell DNA Recombination T Cell Differentiation In Thymus Somatic Diversification Of Immunoglobulins Fibroblast Proliferation
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