RPL4 and IL32

Number of citations of the paper that reports this interaction (PMID 25178676)
0

Data Source:
BioGRID (two hybrid)

		RPL4	IL32
Gene Name		ribosomal protein L4	interleukin 32
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Cytosol Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit Ribonucleoprotein Complex Extracellular Vesicular Exosome	Extracellular Space Membrane
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding Poly(A) RNA Binding	Cytokine Activity Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process	Defense Response Immune Response Cell Adhesion
Pathways		Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS			HIV-1 susceptibility ( 22174851)
Protein-Protein Interactions		10 interactors: APBB1 APOE IL32 MAP3K14 MYB NDRG1 PBX2 PIN1 PRPF40A SORBS1	10 interactors: C1QB HSPA8 KPNA5 NDN NQO2 PRTN3 RPL4 SNRNP70 TUT1 ZFPM2
Entrez ID		6124	9235
HPRD ID		01607	09346
Ensembl ID		ENSG00000174444	ENSG00000008517
Uniprot IDs		H3BM89 P36578	C6GKH1 G3LU47 P24001
PDB IDs		3J3B
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Component Organization Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Cytokinesis Positive Regulation Of Lipid Biosynthetic Process Regulation Of Cell Cycle Positive Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Positive Regulation Of Dendritic Spine Maintenance Negative Regulation Of Dendritic Spine Maintenance Negative Regulation Of Phospholipid Efflux Negative Regulation Of Lipid Transport Across Blood Brain Barrier Positive Regulation Of Lipid Transport Across Blood Brain Barrier Negative Regulation Of Thymidylate Synthase Biosynthetic Process Positive Regulation Of Postsynaptic Membrane Organization Negative Regulation Of Postsynaptic Membrane Organization Response To Abiotic Stimulus Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Activation Positive Regulation Of Neurofibrillary Tangle Assembly Negative Regulation Of Presynaptic Membrane Organization Positive Regulation Of Presynaptic Membrane Organization Regulation Of Cell Cycle Process Immune System Process Regulation Of Protein Metabolic Process Response To Stress Positive Regulation Of Protein Metabolic Process Positive Regulation Of Phospholipid Efflux Negative Regulation Of Cholesterol Biosynthetic Process Regulation Of Postsynaptic Membrane Organization Very-low-density Lipoprotein Particle Clearance Regulation Of Lipid Biosynthetic Process Cellular Response To Cytokine Stimulus Cell Cycle Regulation Of MAPK Cascade Negative Regulation Of MAPK Cascade Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Regulation Of Tau-protein Kinase Activity Negative Regulation Of Cholesterol Efflux N-methyl-D-aspartate Receptor Clustering Regulation Of Presynaptic Membrane Organization Negative Regulation Of Dendritic Spine Development High-density Lipoprotein Particle Clearance Positive Regulation Of Macromolecule Biosynthetic Process Glial Cell Differentiation Response To Cytokine Regulation Of Beta-amyloid Clearance Positive Regulation Of Inclusion Body Assembly Positive Regulation Of Spindle Checkpoint Very-low-density Lipoprotein Particle Remodeling	Positive Regulation Of MRNA Splicing, Via Spliceosome MRNA Metabolic Process Positive Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Fibril Organization Regulation Of MRNA Processing MRNA Processing Regulation Of RNA Splicing RNA Metabolic Process Right Ventricular Cardiac Muscle Tissue Morphogenesis Gene Expression Regulation Of Fibril Organization RNA Processing Negative Regulation Of Female Gonad Development Clathrin Coat Disassembly Cellular Protein Complex Disassembly Mature Conventional Dendritic Cell Differentiation Protein Complex Disassembly Gonadal Mesoderm Development MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Positive Regulation Of Male Gonad Development Regulation Of Female Gonad Development Negative Regulation Of Phagocytosis Nucleobase-containing Compound Metabolic Process
Tagcloud ?		acetyl acetyltransferases begins biogenesis biosynthesis building creb deacetylases e2f e2f1 hub lys nucleolar occupancy orchestrated pan ribosomal ribosome rpl9 rps rps24 rps27a rps6 rrna rrnas sp1 synchronized trimethyl	attempt basal cancers candidate datasets define defining designated differential geo hyperplastic incredible luminal mb231 mcf7 mda microarrays omnibus past progesterone public publically search suitable tma tmas tnbc triple validation
Tagcloud (Difference) ?		acetyl acetyltransferases begins biogenesis biosynthesis building creb deacetylases e2f e2f1 hub lys nucleolar occupancy orchestrated pan ribosomal ribosome rpl9 rps rps24 rps27a rps6 rrna rrnas sp1 synchronized trimethyl	attempt basal cancers candidate datasets define defining designated differential geo hyperplastic incredible luminal mb231 mcf7 mda microarrays omnibus past progesterone public publically search suitable tma tmas tnbc triple validation
Tagcloud (Intersection) ?