RLN2 and RXFP1

Number of citations of the paper that reports this interaction (PubMedID 15649866)
0

Data Source:
HPRD (in vitro)

		RLN2	RXFP1
Description		relaxin 2	relaxin family peptide receptor 1
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GO Annotations	Cellular Component	Extracellular Region	Plasma Membrane Membrane
	Molecular Function	Hormone Activity	G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Hormone Binding Metal Ion Binding
	Biological Process	Signal Transduction Female Pregnancy Positive Regulation Of Gene Expression Positive Regulation Of Angiogenesis Regulation Of Catalytic Activity	Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Parturition Hormone-mediated Signaling Pathway Extracellular Matrix Organization Myofibroblast Differentiation Lung Connective Tissue Development Nipple Morphogenesis
Pathways		G alpha (s) signalling events Relaxin receptors	G alpha (s) signalling events Relaxin receptors
Drugs
Diseases
GWAS			Acute lymphoblastic leukemia (childhood) ( 22076464) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		2 interacting genes: RXFP1 RXFP2	4 interacting genes: RLN1 RLN2 RLN3 SRPK2
Entrez ID		6019	59350
HPRD ID		01561	05975
Ensembl ID		ENSG00000107014	ENSG00000171509
Uniprot IDs		P04090	A0A087WWV0 A0A0A0MT52 B3KV27 B4DGP2 E9PCA3 Q59H16 Q9HBX9
PDB IDs		2MV1 6RLX	2JM4 2M7P 7TMW
Enriched GO Terms of Interacting Partners?		G Protein-coupled Peptide Receptor Activity Hormone-mediated Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Nipple Morphogenesis Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Lung Connective Tissue Development G Protein-coupled Receptor Activity Myofibroblast Differentiation Parturition Protein-hormone Receptor Activity Hormone Binding G Protein-coupled Receptor Signaling Pathway Oocyte Maturation Peptide Hormone Binding Reproductive Process Connective Tissue Development Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Male Gonad Development Gonad Development Cell Maturation	Hormone Activity Female Pregnancy Nuclear Speck Organization R-loop Processing
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