RXFP1 and RLN2

Number of citations of the paper that reports this interaction (PubMedID 15649866)
0

Data Source:
HPRD (in vitro)

		RXFP1	RLN2
Description		relaxin family peptide receptor 1	relaxin 2
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GO Annotations	Cellular Component	Plasma Membrane Membrane	Extracellular Region
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Hormone Binding Metal Ion Binding	Hormone Activity
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Parturition Hormone-mediated Signaling Pathway Extracellular Matrix Organization Myofibroblast Differentiation Lung Connective Tissue Development Nipple Morphogenesis	Signal Transduction Female Pregnancy Positive Regulation Of Gene Expression Positive Regulation Of Angiogenesis Regulation Of Catalytic Activity
Pathways		G alpha (s) signalling events Relaxin receptors	G alpha (s) signalling events Relaxin receptors
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 22076464) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		4 interacting genes: RLN1 RLN2 RLN3 SRPK2	2 interacting genes: RXFP1 RXFP2
Entrez ID		59350	6019
HPRD ID		05975	01561
Ensembl ID		ENSG00000171509	ENSG00000107014
Uniprot IDs		A0A087WWV0 A0A0A0MT52 B3KV27 B4DGP2 E9PCA3 Q59H16 Q9HBX9	P04090
PDB IDs		2JM4 2M7P 7TMW	2MV1 6RLX
Enriched GO Terms of Interacting Partners?		Hormone Activity Female Pregnancy Nuclear Speck Organization R-loop Processing	G Protein-coupled Peptide Receptor Activity Hormone-mediated Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Nipple Morphogenesis Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Lung Connective Tissue Development G Protein-coupled Receptor Activity Myofibroblast Differentiation Parturition Protein-hormone Receptor Activity Hormone Binding G Protein-coupled Receptor Signaling Pathway Oocyte Maturation Peptide Hormone Binding Reproductive Process Connective Tissue Development Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Male Gonad Development Gonad Development Cell Maturation
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