RGR

Description		retinal G protein coupled receptor
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Photoreceptor Activity Photoreceptor Activity
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Visual Perception Phototransduction Detection Of Visible Light Cellular Response To Light Stimulus
Pathways		G alpha (i) signalling events Opsins
Drugs
Diseases		Retinitis pigmentosa (RP)
GWAS		High myopia ( 31816047) Myopia ( 27182965) Refractive error ( 32231278)
Interacting Genes		7 interacting genes: ADRB2 CCR2 F2RL1 KIFBP RDH5 TRIM55 TRIM63
Entrez ID		5995
HPRD ID		02642
Ensembl ID		ENSG00000148604
Uniprot IDs		A0A0S2Z494 A0A0S2Z498 P47804
PDB IDs
Enriched GO Terms of Interacting Partners?		Macrophage Migration Vasodilation Positive Regulation Of Protein-containing Complex Disassembly G Protein-coupled Receptor Activity Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Mini Excitatory Postsynaptic Potential System Process Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Positive Regulation Of Type II Interferon Production Leukocyte Migration Positive Regulation Of Renin Secretion Into Blood Stream 11-cis-retinol Dehydrogenase (NAD+) Activity Negative Regulation Of Eosinophil Degranulation Positive Regulation Of Astrocyte Chemotaxis T-helper 17 Cell Chemotaxis Chemokine (C-C Motif) Ligand 12 Binding Chemokine (C-C Motif) Ligand 2 Binding Beta2-adrenergic Receptor Activity Negative Regulation Of Multicellular Organismal Process Positive Regulation Of Cold-induced Thermogenesis Proteinase-activated Receptor Activity Immune Response Positive Regulation Of Leukocyte Chemotaxis Positive Regulation Of Eosinophil Degranulation Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Mononuclear Cell Migration Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Positive Regulation Of Immune Complex Clearance By Monocytes And Macrophages Positive Regulation Of Thymocyte Migration Positive Regulation Of CD8-positive, Alpha-beta T Cell Extravasation Chemokine (C-C Motif) Ligand 7 Binding Positive Regulation Of Hematopoietic Stem Cell Migration Regulation Of Astrocyte Chemotaxis Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Beta-adrenergic Receptor Activity Regulation Of System Process Regulation Of Protein-containing Complex Disassembly Regulation Of Cytokine Production Involved In Immune Response Regulation Of Regulated Secretory Pathway Regulation Of Type II Interferon Production Positive Regulation Of Glomerular Filtration Defense Response Regulation Of Renin Secretion Into Blood Stream Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Myeloid Leukocyte Migration Regulation Of Thymocyte Migration Regulation Of Immune Complex Clearance By Monocytes And Macrophages Blood Vessel Diameter Maintenance Norepinephrine Binding
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