RBM25 and SRRM4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RBM25	SRRM4
Description		RNA binding motif protein 25	serine/arginine repetitive matrix 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Speck	Nucleus
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding	RNA Binding MRNA Binding Protein Binding Identical Protein Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Regulation Of Apoptotic Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Nervous System Development Sensory Perception Of Sound RNA Splicing Cell Differentiation Neuron Maturation Regulation Of RNA Splicing
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Pulse pressure ( 30578418) Refractive error ( 32231278)	Cerebrospinal fluid t-tau levels in normal cognition ( 29274321) Facial morphology (factor 3, length of philtrum) ( 28441456) Loneliness ( 27629369) Loneliness (linear analysis) ( 27629369) Photic sneeze reflex ( 27182965) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576) Stroke ( 32693751)
Interacting Genes		10 interacting genes: DANCR GOLGA2 HSPB1 PRPF31 PVT1 RBM23 RBM39 RNF10 SRRM4 UBE2I	34 interacting genes: - AKAP17A ARL6IP4 C16orf87 C1orf35 CACNA1A CDC37 CLK1 CLK4 FAM9B LUC7L LUC7L2 LUZP4 MCRS1 PRPF38A RBM25 RBM39 RBMX2 RNPS1 RSRC1 SNIP1 SNRNP70 SREK1 SRRM1 SRSF11 SRSF4 TBC1D26 U2AF1 WDR5 ZNF124 ZNF286A ZNF699 ZRSR2 ZRSR2P1
Entrez ID		58517	84530
HPRD ID		15229	13897
Ensembl ID		ENSG00000119707	ENSG00000139767
Uniprot IDs		P49756	A7MD48 V5T9A0
PDB IDs		3V53
Enriched GO Terms of Interacting Partners?		U1 SnRNP Binding Regulation Of MRNA Splicing, Via Spliceosome RNA Splicing RNA Binding MRNA Processing Regulation Of MRNA Processing Regulation Of RNA Splicing MRNA Metabolic Process Negative Regulation Of Protein Kinase C Signaling SUMO Conjugating Enzyme Activity Ribonucleoprotein Complex Localization Regulation Of MRNA Metabolic Process RNA Processing U4atac SnRNP Protein Kinase C Inhibitor Activity RING-like Zinc Finger Domain Binding SnRNP Binding U4atac SnRNA Binding Positive Regulation Of Protein Glycosylation SUMO Ligase Complex HLH Domain Binding Regulation Of Protein Kinase C Signaling Small Protein Activating Enzyme Binding Postsynapse To Nucleus Signaling Pathway Extrinsic Component Of Postsynaptic Density Membrane SnoRNA Localization	RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing RNA Splicing, Via Transesterification Reactions Nuclear Speck Spliceosomal Complex RNA Binding MRNA Splicing, Via Spliceosome Regulation Of RNA Splicing RNA Metabolic Process Nucleic Acid Binding Nucleic Acid Metabolic Process Nucleus Regulation Of MRNA Splicing, Via Spliceosome Pre-mRNA 3'-splice Site Binding RS Domain Binding U2AF Complex Regulation Of MRNA Processing Nucleobase-containing Compound Metabolic Process U2-type Prespliceosome U1 SnRNP MRNA Binding Regulation Of MRNA Metabolic Process Protein-RNA Complex Assembly U1 SnRNP Binding Spliceosomal Complex Assembly U2-type Precatalytic Spliceosome NSL Complex Regulation Of Alternative MRNA Splicing, Via Spliceosome Nucleoplasm Precatalytic Spliceosome Negative Regulation Of MRNA Splicing, Via Spliceosome Histone Acetyltransferase Complex U2-type Prespliceosome Assembly Negative Regulation Of RNA Splicing U2 SnRNP Protein Serine/threonine/tyrosine Kinase Activity MLL1 Complex Histone H3Q5ser Reader Activity MRNA Splice Site Recognition Macromolecule Metabolic Process Negative Regulation Of Protein Refolding Histone H3K4me1 Reader Activity HSP90-CDC37 Chaperone Complex
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