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BBS1 and PAX2
Number of citations of the paper that reports this interaction (PubMedID
18000879
)
0
Data Source:
BioGRID
(two hybrid)
BBS1
PAX2
Description
Bardet-Biedl syndrome 1
paired box 2
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Centrosome
Cytosol
Cytoskeleton
Plasma Membrane
Cilium
Axoneme
Membrane
Motile Cilium
Centriolar Satellite
BBSome
Cell Projection
Ciliary Membrane
Chromatin
Nucleus
Nucleoplasm
Microtubule Organizing Center
Protein-containing Complex
Protein-DNA Complex
Centriolar Satellite
Molecular Function
Signaling Receptor Binding
Patched Binding
Smoothened Binding
Protein Binding
Phosphoprotein Binding
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Transcription Cis-regulatory Region Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Cis-regulatory Region Sequence-specific DNA Binding
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Transcription Factor Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Microtubule Cytoskeleton Organization
Neuron Migration
Retina Homeostasis
Lipid Metabolic Process
Visual Perception
Sensory Perception Of Smell
Intracellular Protein Localization
Photoreceptor Cell Morphogenesis
Fertilization
Protein Transport
Dendrite Development
Ventricular System Development
Striatum Development
Hippocampus Development
Cerebral Cortex Development
Cell Projection Organization
Adult Behavior
Response To Endoplasmic Reticulum Stress
Olfactory Behavior
Hormone Metabolic Process
Golgi To Plasma Membrane Protein Transport
Fat Cell Differentiation
Photoreceptor Cell Maintenance
Brain Morphogenesis
Cartilage Development
Retina Development In Camera-type Eye
Cilium Assembly
Regulation Of Cilium Beat Frequency Involved In Ciliary Motility
Neural Precursor Cell Proliferation
Protein Localization To Cilium
Non-motile Cilium Assembly
Urogenital System Development
Branching Involved In Ureteric Bud Morphogenesis
Cell Fate Determination
Mesonephros Development
Neural Tube Closure
Optic Cup Morphogenesis Involved In Camera-type Eye Development
Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis
Retinal Pigment Epithelium Development
Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
Nervous System Development
Axonogenesis
Sensory Organ Development
Mesodermal Cell Fate Specification
Visual Perception
Glial Cell Differentiation
Optic Nerve Development
Optic Nerve Morphogenesis
Optic Nerve Structural Organization
Vestibulocochlear Nerve Formation
Cell Differentiation
Regulation Of Metanephros Size
Ureter Maturation
Pronephric Field Specification
Inner Ear Morphogenesis
Camera-type Eye Development
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Negative Regulation Of DNA-templated Transcription
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Animal Organ Development
System Development
Pronephros Development
Brain Morphogenesis
Stem Cell Differentiation
Positive Regulation Of Epithelial Cell Proliferation
Mesenchymal To Epithelial Transition
Optic Chiasma Development
Cellular Response To Retinoic Acid
Cellular Response To Glucose Stimulus
Metanephric Mesenchyme Development
Positive Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis
Metanephric Mesenchymal Cell Differentiation
Nephric Duct Formation
Ureter Development
Metanephric Collecting Duct Development
Metanephric Epithelium Development
Metanephric Distal Convoluted Tubule Development
Metanephric Nephron Tubule Formation
Positive Regulation Of Metanephric Glomerulus Development
Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Metanephric Nephron Morphogenesis
Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation
Cochlea Development
Cochlea Morphogenesis
Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Metanephros Development
Negative Regulation Of Apoptotic Process Involved In Metanephric Collecting Duct Development
Negative Regulation Of Apoptotic Process Involved In Metanephric Nephron Tubule Development
Negative Regulation Of Reactive Oxygen Species Metabolic Process
Positive Regulation Of Metanephric DCT Cell Differentiation
Positive Regulation Of Optic Nerve Formation
Pathways
BBSome-mediated cargo-targeting to cilium
Formation of intermediate mesoderm
Formation of the nephric duct
Formation of the ureteric bud
Drugs
Diseases
Bardet-Biedl syndrome (BBS)
Renal coloboma syndrome (RCS); Papillorenal syndrome
GWAS
Bipolar disorder (
21926972
)
Height (
28552196
)
Adult body size (
32376654
)
Alcohol consumption (drinks per week) (
30679032
)
Alzheimer's disease (
20061627
)
Bitter alcoholic beverage consumption (
31046077
)
BMI (adjusted for smoking behaviour) (
28443625
)
Body mass index (
28892062
)
Body mass index (joint analysis main effects and smoking interaction) (
28443625
)
Body size at age 10 (
32376654
)
Cerebrospinal fluid t-tau:AB1-42 ratio (
30153862
)
Diastolic blood pressure (
27841878
)
Heart rate increase in response to exercise (
29497042
)
Heart rate response to exercise (
29769521
)
Heart rate response to recovery post exercise (
29769521
)
Heart rate response to recovery post exercise (10 sec) (
29497042
)
Heart rate response to recovery post exercise (20 sec) (
29497042
)
Heart rate response to recovery post exercise (30 sec) (
29497042
)
Heart rate response to recovery post exercise (40 sec) (
29497042
)
Heart rate response to recovery post exercise (50 sec) (
29497042
)
Refractive error (
32231278
)
Regular attendance at a pub or social club (
29970889
)
Systolic blood pressure (
30578418
28135244
27841878
)
Interacting Genes
13 interacting genes:
BHMT
CALCA
DCTN1
EEF1A1
EIF3A
EPAS1
EXOC7
FHOD1
HSCB
KRT18
PARK7
PAX2
TSPAN7
28 interacting genes:
BBS1
BBS2
BBS4
BBS7
BEX1
BLID
GLCE
HNF1B
ID2
IL13RA2
KLK6
KLK9
MAPK8
MAPK8IP1
MRC2
NFIC
NFIX
NSD3
PAXIP1
PRDM14
RASL10B
RB1
SFRP2
SNAI1
TRIM25
VHL
VPS45
WT1
Entrez ID
582
5076
HPRD ID
01950
01330
Ensembl ID
ENSG00000174483
ENSG00000075891
Uniprot IDs
Q8NFJ9
A0A9L9PXU6
A0A9L9PYK3
Q02962
Q5SZP1
PDB IDs
6XT9
Enriched GO Terms of Interacting Partners
?
Regulation Of Mitochondrial Membrane Potential
Chemical Homeostasis
Homeostatic Process
Cellular Homeostasis
Regulation Of Programmed Cell Death
Regulation Of Aerobic Respiration
Cytoplasm
Positive Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate
Regulation Of Cellular Respiration
Cytosol
Epithelial Cell Proliferation
Extrinsic Apoptotic Signaling Pathway
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress
Regulation Of Release Of Cytochrome C From Mitochondria
Negative Regulation Of Programmed Cell Death
Release Of Cytochrome C From Mitochondria
Mitochondrion Organization
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Regulation Of Autophagy
Positive Regulation Of Release Of Cytochrome C From Mitochondria
Regulation Of Protein Metabolic Process
Intracellular Chemical Homeostasis
Regulation Of Calcium Ion Transport Into Cytosol
Blood Vessel Remodeling
Regulation Of Homocysteine Metabolic Process
'de Novo' L-methionine Biosynthetic Process
Axon
Nucleus Localization
Nuclear Migration
Centriolar Satellite
Microtubule Organizing Center
Negative Regulation Of Reactive Oxygen Species Metabolic Process
Optic Chiasma Development
Positive Regulation Of Optic Nerve Formation
Proline Dipeptidase Activity
Eye Pigmentation
Glyoxal Catabolic Process
L-dopa Decarboxylase Activator Activity
Guanine Deglycation
Protein Deglycase Activity
Glyoxalase (glycolic Acid-forming) Activity
Glycolate Biosynthetic Process
Guanine Deglycation, Methylglyoxal Removal
Guanine Deglycation, Glyoxal Removal
Detoxification Of Mercury Ion
Negative Regulation Of Death-inducing Signaling Complex Assembly
Cellular Response To Glyoxal
Glyoxal Metabolic Process
Positive Regulation Of L-dopa Biosynthetic Process
Tyrosine 3-monooxygenase Activator Activity
BBSome
Positive Regulation Of RNA Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Anatomical Structure Morphogenesis
Negative Regulation Of Metabolic Process
Regulation Of Cilium Movement
Regulation Of Cilium Beat Frequency Involved In Ciliary Motility
Negative Regulation Of Macromolecule Biosynthetic Process
Regulation Of Gene Expression
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Non-motile Cilium Assembly
Regulation Of Microtubule-based Movement
Striatum Development
Ciliary Membrane
Regulation Of Cilium Beat Frequency
Fat Cell Differentiation
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Brain Morphogenesis
Digestive Tract Morphogenesis
Cell Morphogenesis Involved In Neuron Differentiation
Melanosome Transport
Positive Regulation Of Biosynthetic Process
Establishment Of Melanosome Localization
Pigment Granule Transport
Melanosome Localization
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Gene Expression
Tube Morphogenesis
Negative Regulation Of RNA Metabolic Process
Pigment Granule Localization
Regulation Of Transcription By RNA Polymerase II
Cell Morphogenesis
Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway
Animal Organ Morphogenesis
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Metabolic Process
Epithelial Tube Morphogenesis
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Tagcloud (Difference)
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Tagcloud (Intersection)
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