TRIB2 and SLAMF7

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		TRIB2	SLAMF7
Gene Name		tribbles pseudokinase 2	SLAM family member 7
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton	Integral Component Of Membrane
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Kinase Inhibitor Activity Transcription Factor Binding Ubiquitin Protein Ligase Binding Ubiquitin-protein Transferase Regulator Activity	Receptor Activity
	Biological Process	Protein Phosphorylation Negative Regulation Of Protein Kinase Activity Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of MAP Kinase Activity Negative Regulation Of Interleukin-10 Biosynthetic Process Negative Regulation Of Fat Cell Differentiation	Cell Adhesion Natural Killer Cell Activation Natural Killer Cell Mediated Cytotoxicity
Pathways
Drugs
Diseases
GWAS		Dental caries ( 23064961) Pericardial fat ( 22589742)	Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		4 interactors: APP PRMT6 SLAMF7 UBQLN4	4 interactors: CLK3 MAK SH2D1A TRIB2
Entrez ID		28951	57823
HPRD ID		18224	09432
Ensembl ID		ENSG00000071575	ENSG00000026751
Uniprot IDs		Q92519	Q9NQ25
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone H3-R2 Methylation Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition	Negative Regulation Of Interleukin-10 Biosynthetic Process Protein Autophosphorylation Protein Phosphorylation
Tagcloud ?		aberrantly activates autoregulatory circuit circuitry core downstream e2a emphasizing feed forming forward gata3 heb interconnected lmo1 loop lymphoblastic myb oncogene oncogenic oppositely partners program regulatory reinforces runx1 stabilizes tal1	antibody autoimmunity biology cd319 compelling cracc cs1 discusses elotuzumab expressed family focuses hematopoietic humanized immunity immunodeficiencies implicated knowledge lymphocytic member mm molecule monoclonal myeloma nearly normal preclinical universally
Tagcloud (Difference) ?		aberrantly activates autoregulatory circuit circuitry core downstream e2a emphasizing feed forming forward gata3 heb interconnected lmo1 loop lymphoblastic myb oncogene oncogenic oppositely partners program regulatory reinforces runx1 stabilizes tal1	antibody autoimmunity biology cd319 compelling cracc cs1 discusses elotuzumab expressed family focuses hematopoietic humanized immunity immunodeficiencies implicated knowledge lymphocytic member mm molecule monoclonal myeloma nearly normal preclinical universally
Tagcloud (Intersection) ?