PTCHD2 and CEACAM5

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		PTCHD2	CEACAM5
Gene Name		patched domain containing 2	carcinoembryonic antigen-related cell adhesion molecule 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Integral Component Of Membrane Nuclear Membrane	Integral Component Of Plasma Membrane Basolateral Plasma Membrane Anchored Component Of Membrane Extracellular Vesicular Exosome Integral Component Of External Side Of Plasma Membrane
	Molecular Function	Molecular_function Hedgehog Receptor Activity	GPI Anchor Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Smoothened Signaling Pathway Regulation Of Lipid Transport Cholesterol Homeostasis	Negative Regulation Of Myotube Differentiation Homotypic Cell-cell Adhesion Negative Regulation Of Apoptotic Process Negative Regulation Of Anoikis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: CA2 CEACAM5 MYCBP RASGRP2	6 interactors: CEACAM1 CEACAM6 EWSR1 HNRNPM PTCHD2 UQCC2
Entrez ID		57540	1048
HPRD ID		13852	00274
Ensembl ID		ENSG00000204624	ENSG00000105388
Uniprot IDs		Q9P2K9	P06731 Q68DM9
PDB IDs			1E07 2QSQ 2QST 2VER
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Dipeptide Transmembrane Transport Regulation Of Chloride Transport Positive Regulation Of Cellular PH Reduction Response To Metal Ion Angiotensin-activated Signaling Pathway Negative Regulation Of Myotube Differentiation Response To Inorganic Substance Positive Regulation Of Synaptic Transmission, GABAergic Negative Regulation Of Anoikis Positive Regulation Of Bone Resorption Cellular Response To Fluid Shear Stress Positive Regulation Of Rap GTPase Activity Regulation Of Anoikis Negative Regulation Of Striated Muscle Cell Differentiation Regulation Of Rap GTPase Activity Regulation Of Rap Protein Signal Transduction Positive Regulation Of Osteoclast Differentiation Positive Regulation Of Tissue Remodeling Bicarbonate Transport Regulation Of Bone Resorption Regulation Of Synaptic Transmission, GABAergic Response To Fluid Shear Stress Response To PH Negative Regulation Of Muscle Cell Differentiation Regulation Of Bone Remodeling One-carbon Metabolic Process Regulation Of Intracellular PH Regulation Of Cellular PH Response To Zinc Ion Cellular Response To Calcium Ion Positive Regulation Of Myeloid Leukocyte Differentiation Regulation Of Myotube Differentiation	Leukocyte Migration Positive Regulation Of Mitochondrial Translation Regulation Of Mitochondrial Translation Regulation Of Oxidative Phosphorylation Mitochondrial Respiratory Chain Complex III Assembly Alternative MRNA Splicing, Via Spliceosome Blood Coagulation Regulation Of Skeletal Muscle Cell Differentiation Hemostasis
Tagcloud ?			adenocarcinoma adenocarcinomas ampulla arising bile bircs bm7 cardia compromising ctc ctcs ducts epcam esophagus great immunomagnetic intestine krt19 muc1 multimarker oncology pancreas pb problematic rectum scgb2a2 stomach vater vu1d9
Tagcloud (Difference) ?			adenocarcinoma adenocarcinomas ampulla arising bile bircs bm7 cardia compromising ctc ctcs ducts epcam esophagus great immunomagnetic intestine krt19 muc1 multimarker oncology pancreas pb problematic rectum scgb2a2 stomach vater vu1d9
Tagcloud (Intersection) ?