CEACAM5 and PTCHD2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		CEACAM5	PTCHD2
Gene Name		carcinoembryonic antigen-related cell adhesion molecule 5	patched domain containing 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Basolateral Plasma Membrane Anchored Component Of Membrane Extracellular Vesicular Exosome Integral Component Of External Side Of Plasma Membrane	Endoplasmic Reticulum Integral Component Of Membrane Nuclear Membrane
	Molecular Function	GPI Anchor Binding Identical Protein Binding Protein Homodimerization Activity	Molecular_function Hedgehog Receptor Activity
	Biological Process	Negative Regulation Of Myotube Differentiation Homotypic Cell-cell Adhesion Negative Regulation Of Apoptotic Process Negative Regulation Of Anoikis	Smoothened Signaling Pathway Regulation Of Lipid Transport Cholesterol Homeostasis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CEACAM1 CEACAM6 EWSR1 HNRNPM PTCHD2 UQCC2	4 interactors: CA2 CEACAM5 MYCBP RASGRP2
Entrez ID		1048	57540
HPRD ID		00274	13852
Ensembl ID		ENSG00000105388	ENSG00000204624
Uniprot IDs		P06731 Q68DM9	Q9P2K9
PDB IDs		1E07 2QSQ 2QST 2VER
Enriched GO Terms of Interacting Partners?		Leukocyte Migration Positive Regulation Of Mitochondrial Translation Regulation Of Mitochondrial Translation Regulation Of Oxidative Phosphorylation Mitochondrial Respiratory Chain Complex III Assembly Alternative MRNA Splicing, Via Spliceosome Blood Coagulation Regulation Of Skeletal Muscle Cell Differentiation Hemostasis	Positive Regulation Of Dipeptide Transmembrane Transport Regulation Of Chloride Transport Positive Regulation Of Cellular PH Reduction Response To Metal Ion Angiotensin-activated Signaling Pathway Negative Regulation Of Myotube Differentiation Response To Inorganic Substance Positive Regulation Of Synaptic Transmission, GABAergic Negative Regulation Of Anoikis Positive Regulation Of Bone Resorption Cellular Response To Fluid Shear Stress Positive Regulation Of Rap GTPase Activity Regulation Of Anoikis Negative Regulation Of Striated Muscle Cell Differentiation Regulation Of Rap GTPase Activity Regulation Of Rap Protein Signal Transduction Positive Regulation Of Osteoclast Differentiation Positive Regulation Of Tissue Remodeling Bicarbonate Transport Regulation Of Bone Resorption Regulation Of Synaptic Transmission, GABAergic Response To Fluid Shear Stress Response To PH Negative Regulation Of Muscle Cell Differentiation Regulation Of Bone Remodeling One-carbon Metabolic Process Regulation Of Intracellular PH Regulation Of Cellular PH Response To Zinc Ion Cellular Response To Calcium Ion Positive Regulation Of Myeloid Leukocyte Differentiation Regulation Of Myotube Differentiation
Tagcloud ?		adenocarcinoma adenocarcinomas ampulla arising bile bircs bm7 cardia compromising ctc ctcs ducts epcam esophagus great immunomagnetic intestine krt19 muc1 multimarker oncology pancreas pb problematic rectum scgb2a2 stomach vater vu1d9
Tagcloud (Difference) ?		adenocarcinoma adenocarcinomas ampulla arising bile bircs bm7 cardia compromising ctc ctcs ducts epcam esophagus great immunomagnetic intestine krt19 muc1 multimarker oncology pancreas pb problematic rectum scgb2a2 stomach vater vu1d9
Tagcloud (Intersection) ?