MIR18B and PDCD11

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR18B	PDCD11
Description		microRNA 18b	programmed cell death 11
Image		No pdb structure
GO Annotations	Cellular Component	RISC Complex	Nucleus Nucleoplasm Nucleolus Cytosol Small-subunit Processome
	Molecular Function	MRNA Base-pairing Post-transcriptional Repressor Activity	Nucleic Acid Binding RNA Binding Protein Binding NF-kappaB Binding
	Biological Process	Negative Regulation Of Epithelial Cell Differentiation MiRNA-mediated Post-transcriptional Gene Silencing	RRNA Processing RNA Processing
Pathways			rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS			Appendicular lean mass ( 33097823) Autism spectrum disorder or schizophrenia ( 28540026) Estimated glomerular filtration rate ( 31152163) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Schizophrenia ( 23974872 25056061) White matter hyperintensity burden ( 25663218)
Interacting Genes		84 interacting genes: APOBEC3B C1QBP CELF1 CELF2 CPSF1 CPSF6 CPSF7 DARS1 DDX1 DDX21 DDX3X DDX3Y DHX36 EIF2AK2 EPRS1 FAM98A FAM98B FUS GRSF1 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT16L1 NUDT21 P3H1 PDCD11 PGAM5 PLOD1 PRMT1 PTBP1 PTBP3 PTCD3 PUF60 PUM1 PURA QARS1 RARS1 RBFOX2 RBM14 RTCB SART3 SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SYNCRIP TAF15 TRA2B TRIM26 TRIM71 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346	77 interacting genes: ERBB2 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NFKB1 RELA RNF10 S100A8
Entrez ID		574033	22984
HPRD ID			18752
Ensembl ID		ENSG00000283931	ENSG00000148843
Uniprot IDs			A0A3B3IUD7 Q14690
PDB IDs			1WI5
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process Nucleic Acid Metabolic Process RNA Splicing MRNA Processing MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process Macromolecule Metabolic Process MRNA Binding Regulation Of MRNA Metabolic Process Regulation Of RNA Splicing Ribonucleoprotein Complex MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Post-transcriptional Regulation Of Gene Expression Nucleoplasm Nucleus Regulation Of Translation Aminoacyl-tRNA Synthetase Multienzyme Complex Catalytic Step 2 Spliceosome Regulation Of Gene Expression Spliceosomal Complex Regulation Of Macromolecule Biosynthetic Process MRNA 3'-UTR Binding Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Macromolecule Metabolic Process MiRNA Binding TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Regulation Of Metabolic Process Negative Regulation Of Translation TRNA Aminoacylation Regulation Of Primary Metabolic Process TRNA Metabolic Process Regulation Of MRNA Stability Cytoplasmic Stress Granule Negative Regulation Of RNA Catabolic Process Regulation Of RNA Stability Negative Regulation Of MRNA Catabolic Process RNA Stabilization Negative Regulation Of Macromolecule Metabolic Process MRNA Stabilization Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of Metabolic Process Positive Regulation Of Cytoplasmic Translation Ligase Activity	MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RISC Complex Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Extracellular Vesicle Negative Regulation Of Translation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process MRNA Destabilization Negative Regulation Of Cytokine Production RNA Destabilization Regulation Of Angiogenesis Regulation Of Vasculature Development Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Regulation Of Macromolecule Metabolic Process Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Locomotion Positive Regulation Of MRNA Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Translation Negative Regulation Of Developmental Process Regulation Of MRNA Stability Regulation Of RNA Stability Extracellular Space Negative Regulation Of Protein Metabolic Process Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Endothelial Cell Migration Regulation Of Cytokine Production Regulation Of Cell Migration Negative Regulation Of Signal Transduction Regulation Of Anatomical Structure Morphogenesis Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cell Motility
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