PDCD11 and MIR199A2

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		PDCD11	MIR199A2
Description		programmed cell death 11	microRNA 199a-2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Small-subunit Processome	RISC Complex
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding NF-kappaB Binding
	Biological Process	RRNA Processing RNA Processing	MiRNA-mediated Post-transcriptional Gene Silencing
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Autism spectrum disorder or schizophrenia ( 28540026) Estimated glomerular filtration rate ( 31152163) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Schizophrenia ( 23974872 25056061) White matter hyperintensity burden ( 25663218)
Interacting Genes		77 interacting genes: ERBB2 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NFKB1 RELA RNF10 S100A8	75 interacting genes: ADARB1 AIMP1 APOBEC3B AQR C1QBP CPSF1 CRTAP DARS1 DDX1 DDX21 DDX3X DHX36 EIF2AK2 EPRS1 ERAL1 FAM98A FAM98B FUS HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KNOP1 LARP7 LIN28A LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT21 PDCD11 PLOD1 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PUM2 QARS1 RARS1 RBFOX2 RBM14 RTCA RTCB SF3A1 SF3B1 SF3B2 SF3B3 SFPQ SPOUT1 STRBP SYNCRIP TAF15 TRA2A TRA2B U2SURP UPF1 UTP20 YBX1 YBX2 YBX3
Entrez ID		22984	406977
HPRD ID		18752
Ensembl ID		ENSG00000148843	ENSG00000208024
Uniprot IDs		A0A3B3IUD7 Q14690
PDB IDs		1WI5
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RISC Complex Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Extracellular Vesicle Negative Regulation Of Translation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process MRNA Destabilization Negative Regulation Of Cytokine Production RNA Destabilization Regulation Of Angiogenesis Regulation Of Vasculature Development Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Regulation Of Macromolecule Metabolic Process Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Locomotion Positive Regulation Of MRNA Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Translation Negative Regulation Of Developmental Process Regulation Of MRNA Stability Regulation Of RNA Stability Extracellular Space Negative Regulation Of Protein Metabolic Process Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Endothelial Cell Migration Regulation Of Cytokine Production Regulation Of Cell Migration Negative Regulation Of Signal Transduction Regulation Of Anatomical Structure Morphogenesis Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cell Motility	RNA Binding RNA Processing Nucleic Acid Binding RNA Metabolic Process RNA Splicing MRNA Processing Nucleic Acid Metabolic Process MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Metabolic Process MRNA Binding MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing Macromolecule Metabolic Process Post-transcriptional Regulation Of Gene Expression Catalytic Step 2 Spliceosome Spliceosomal Complex Ribonucleoprotein Complex Nucleus Nucleoplasm Negative Regulation Of MRNA Metabolic Process Regulation Of Translation Aminoacyl-tRNA Synthetase Multienzyme Complex MRNA 3'-UTR Binding Regulation Of MRNA Processing MiRNA Binding Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Gene Expression Cytoplasmic Stress Granule Negative Regulation Of RNA Catabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of MRNA Catabolic Process Regulation Of MRNA Stability RNA Stabilization Regulation Of RNA Stability MRNA Stabilization Regulation Of Primary Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Cytoplasmic Translation Positive Regulation Of Gene Expression Negative Regulation Of Translation Negative Regulation Of Metabolic Process CRD-mediated MRNA Stabilization MRNA 5'-UTR Binding Positive Regulation Of Macromolecule Biosynthetic Process P-body Regulation Of Cytoplasmic Translation
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