CLK4 and UBL5

Number of citations of the paper that reports this interaction (PubMedID 12824502)
21

Data Source:
BioGRID (pull down)
HPRD (two hybrid)

		CLK4	UBL5
Description		CDC like kinase 4	ubiquitin like 5
Image
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cytoplasm Cajal Body
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity	Protein Binding Protein Tag Activity
	Biological Process	Regulation Of RNA Splicing	MRNA Splicing, Via Spliceosome Protein Modification Process Positive Regulation Of Protein Targeting To Mitochondrion
Pathways			mRNA Splicing - Major Pathway
Drugs		Fostamatinib
Diseases
GWAS		Urate levels in obese individuals ( 25811787)	Sleep duration ( 30531941) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Interacting Genes		15 interacting genes: CLASRP HSPB2 KPNA1 KRTAP10-3 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 MITF RNF181 SRPK1 SRRM4 SRSF1 SRSF10 UBL5	49 interacting genes: BEND7 BIN3 C1QTNF1 CCDC196 CCDC28B CERCAM CLK1 CLK2 CLK4 CTAG1A CTAG1B DMRTB1 FAM50B FANCI GCSAML HESX1 HID1 HMGXB4 HOXA1 HSPB2 KRTAP10-8 KRTAP13-3 LENG1 MBD3L1 NCOA5 NFYA NME4 NRIP3 PAX4 PHACTR3 PINX1 PRMT8 PSME2 SART1 SEPTIN2 SERTAD3 SF1 SMCP SPANXB1 SPATC1L TEX35 THAP3 TLE5 TRIM27 TRIM39 WASHC1 ZFP41 ZNF124 ZNF618
Entrez ID		57396	59286
HPRD ID		12140	06028
Ensembl ID		ENSG00000113240	ENSG00000198258
Uniprot IDs		Q9HAZ1	A0A024R7B0 Q9BZL1
PDB IDs		6FYV	1P0R 4PYU 6AHD 7AAV 7ABF 7ABG 7ABI 8H6K 8Q7N 8QO9
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament RNA Splicing MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing MRNA Metabolic Process RS Domain Binding Regulation Of RNA Splicing Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Processing Regulation Of MRNA Metabolic Process MRNA Splice Site Recognition RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Protein-RNA Complex Assembly MRNA Splicing, Via Spliceosome MRNA Binding Melanocyte Apoptotic Process Protein Localization To P-body Satellite Cell Activation Involved In Skeletal Muscle Regeneration Somatic Muscle Development Negative Regulation Of MRNA Metabolic Process DNA Topoisomerase Binding	Identical Protein Binding Protein Serine/threonine/tyrosine Kinase Activity
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