CLDND1 and ZDHHC4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CLDND1	ZDHHC4
Description		claudin domain containing 1	zDHHC palmitoyltransferase 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Bicellular Tight Junction Cell Surface Membrane Apical Plasma Membrane Anchoring Junction	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding Palmitoyltransferase Activity Transferase Activity Acyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity
	Biological Process		Cytoplasmic Pattern Recognition Receptor Signaling Pathway Protein Targeting To Membrane Positive Regulation Of Cell Migration Negative Regulation Of Cell Migration Positive Regulation Of Innate Immune Response Cellular Response To Diacyl Bacterial Lipopeptide Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Post bronchodilator FEV1/FVC ratio ( 26634245)	Body mass index ( 26426971)
Interacting Genes		5 interacting genes: CXCR1 DRD2 GPR61 MTNR1B ZDHHC4	4 interacting genes: CLDND1 DRD2 SMAD3 TRARG1
Entrez ID		56650	55146
HPRD ID		12822	15719
Ensembl ID		ENSG00000080822	ENSG00000136247
Uniprot IDs		A0A0R4J2F2 Q9NY35	Q9NPG8
PDB IDs
Enriched GO Terms of Interacting Partners?		G Protein-coupled Receptor Activity Negative Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Circadian Sleep/wake Cycle, Sleep G Protein-coupled Receptor Signaling Pathway Regulation Of Circadian Sleep/wake Cycle Negative Regulation Of Insulin Secretion Negative Regulation Of Peptide Secretion Negative Regulation Of Protein Secretion Negative Regulation Of Hormone Secretion Receptor Internalization Regulation Of Behavior Ligand-independent Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Peptide Hormone Secretion Negative Regulation Of Secretion By Cell Regulation Of Circadian Rhythm Dopamine Binding Dopamine Neurotransmitter Receptor Activity Cerebral Cortex GABAergic Interneuron Migration Plasma Membrane Regulation Of Insulin Secretion Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Circadian Sleep/wake Cycle, Sleep Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway G Protein-coupled Receptor Complex Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go Negative Regulation Of Dephosphorylation Positive Regulation Of Renal Sodium Excretion Positive Regulation Of Glial Cell-derived Neurotrophic Factor Production Negative Regulation Of Protein Localization Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Hyaloid Vascular Plexus Regression Negative Regulation Of Secretion Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Orbitofrontal Cortex Development Negative Regulation Of Protein Transport Branching Morphogenesis Of A Nerve Negative Regulation Of Dopamine Secretion Receptor-mediated Endocytosis Positive Regulation Of Neurotransmitter Uptake Negative Regulation Of Establishment Of Protein Localization Regulation Of Locomotion Involved In Locomotory Behavior Signal Transduction Negative Regulation Of Dopamine Receptor Signaling Pathway Interleukin-8-mediated Signaling Pathway Interleukin-8 Binding Interleukin-8 Receptor Activity Melatonin Receptor Activity Positive Regulation Of Circadian Sleep/wake Cycle, Sleep Negative Regulation Of CGMP-mediated Signaling Regulation Of Neuronal Action Potential	Negative Regulation Of Cytosolic Calcium Ion Concentration Negative Regulation Of Synaptic Transmission, Glutamatergic Response To Histamine Regulation Of Synapse Structural Plasticity Dopamine Binding Regulation Of Renal Sodium Excretion Response To Oxygen Levels Negative Regulation Of Defense Response Dopamine Neurotransmitter Receptor Activity Cellular Response To Oxygen-containing Compound Cerebral Cortex GABAergic Interneuron Migration Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Circadian Sleep/wake Cycle, Sleep Regulation Of Dopamine Receptor Signaling Pathway Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway G Protein-coupled Receptor Complex Catecholamine Uptake Dopamine Uptake Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go Adenohypophysis Development Negative Regulation Of Dephosphorylation Response To Inactivity Response To Decreased Oxygen Levels Positive Regulation Of Renal Sodium Excretion Positive Regulation Of Glial Cell-derived Neurotrophic Factor Production Negative Regulation Of Neuron Migration Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Hyaloid Vascular Plexus Regression Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Orbitofrontal Cortex Development Neuron-neuron Synaptic Transmission Interneuron Migration From The Subpallium To The Cortex Response To Hypoxia Branching Morphogenesis Of A Nerve Negative Regulation Of Dopamine Secretion Peristalsis Positive Regulation Of Growth Hormone Secretion Positive Regulation Of Neurotransmitter Uptake Response To Wounding Regulation Of Dopamine Uptake Involved In Synaptic Transmission Heterotrimeric G-protein Binding Regulation Of Locomotion Involved In Locomotory Behavior Positive Regulation Of Urine Volume Regulation Of Blood Pressure Behavioral Response To Ethanol Negative Regulation Of Dopamine Receptor Signaling Pathway Nervous System Process Involved In Regulation Of Systemic Arterial Blood Pressure Phospholipase C-activating Dopamine Receptor Signaling Pathway Drinking Behavior Sterol Response Element Binding
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