EIF5A2 and RAB30

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		EIF5A2	RAB30
Gene Name		eukaryotic translation initiation factor 5A2	RAB30, member RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Pore Endoplasmic Reticulum Membrane Cytosol	Cytoplasm Golgi Stack Cis-Golgi Network Trans-Golgi Network Membrane Golgi Cisterna
	Molecular Function	Translation Elongation Factor Activity Protein Binding Ribosome Binding	GTPase Activity GTP Binding GDP Binding
	Biological Process	Translational Frameshifting Spermatogenesis Positive Regulation Of Cell Proliferation Peptidyl-lysine Modification To Peptidyl-hypusine Polyamine Homeostasis Protein Transport Post-translational Protein Modification Cellular Protein Metabolic Process Positive Regulation Of Translational Elongation Positive Regulation Of Translational Termination MRNA Transport	Intracellular Protein Transport Golgi Organization Metabolic Process Rab Protein Signal Transduction Lipid Particle Organization
Pathways		Post-translational protein modification Hypusine synthesis from eIF5A-lysine Gamma carboxylation, hypusine formation and arylsulfatase activation
Drugs
Diseases
GWAS			Age-related macular degeneration ( 23326517) Economic and political preferences (feminism/equality) ( 22566634)
Protein-Protein Interactions		7 interactors: CDC23 DHPS NIF3L1 PTBP2 RAB30 REL SDCBP	2 interactors: EIF5A2 SMAD1
Entrez ID		56648	27314
HPRD ID		10426	05750
Ensembl ID		ENSG00000163577	ENSG00000137502
Uniprot IDs		Q9GZV4	A8K5R1 Q15771 Q6MZH2
PDB IDs			2EW1
Enriched GO Terms of Interacting Partners?			Polyamine Homeostasis Posttranscriptional Regulation Of Gene Expression Translational Frameshifting Positive Regulation Of Translational Termination Primary MiRNA Processing Positive Regulation Of Translational Elongation Osteoblast Fate Commitment Regulation Of Translational Termination Gamete Generation SMAD Protein Complex Assembly Sexual Reproduction Multicellular Organismal Reproductive Process Mesodermal Cell Fate Commitment Peptidyl-lysine Modification To Peptidyl-hypusine Multicellular Organism Reproduction Cardiac Muscle Cell Proliferation Production Of MiRNAs Involved In Gene Silencing By MiRNA Cellular Response To BMP Stimulus Reproduction Mesodermal Cell Differentiation Positive Regulation Of Protein Complex Disassembly Cell Fate Commitment Involved In Formation Of Primary Germ Layer Cardiac Muscle Tissue Growth Single Organism Reproductive Process Negative Regulation Of Muscle Cell Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Positive Regulation Of Dendrite Morphogenesis Gene Silencing By MiRNA Cellular Response To DsRNA Reproductive Process Positive Regulation Of Cartilage Development Posttranscriptional Gene Silencing Homeostatic Process Regulation Of Cell Proliferation Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Muscle Cell Apoptotic Process Positive Regulation Of Gene Expression Positive Regulation Of Dendrite Development Positive Regulation Of Cellular Biosynthetic Process Gene Silencing By RNA Regulation Of Dendrite Morphogenesis Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Translation Response To DsRNA BMP Signaling Pathway Regulation Of Cellular Component Organization Midbrain Development Mesoderm Formation Regulation Of Cartilage Development Embryonic Pattern Specification
Tagcloud ?		aggressiveness blotting cadherin cck cyclind1 cyclind3 d3 downregulating expressions gastric ges hgc27 immortalized interfering invasion knockdown metallopeptidase mkn28 mta1 mucosal myc qrt silenced sirna suppressing transwell vimentin vimintin	colocalized constitutively controlling elucidated gtpase healing immunocytochemical interacting interacts isoforms knockdown lc macrophages munc13 positively rab27b rab33a rab37 rab3b rab40c raw264 secretion sirna skin tnf upregulated vesicles wound
Tagcloud (Difference) ?		aggressiveness blotting cadherin cck cyclind1 cyclind3 d3 downregulating expressions gastric ges hgc27 immortalized interfering invasion metallopeptidase mkn28 mta1 mucosal myc qrt silenced suppressing transwell vimentin vimintin	colocalized constitutively controlling elucidated gtpase healing immunocytochemical interacting interacts isoforms lc macrophages munc13 positively rab27b rab33a rab37 rab3b rab40c raw264 secretion skin tnf upregulated vesicles wound
Tagcloud (Intersection) ?		knockdown sirna