ERO1B and TARBP1

		ERO1B	TARBP1
Description		endoplasmic reticulum oxidoreductase 1 beta	tRNA guanosine 2 -O-methyltransferase TARBP1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Membrane	Nucleus
	Molecular Function	Protein Binding Protein-disulfide Reductase Activity Disulfide Oxidoreductase Activity Oxidoreductase Activity Thiol Oxidase Activity Unfolded Protein Binding FAD Binding	TRNA Binding RNA Binding Methyltransferase Activity RNA Methyltransferase Activity TRNA (guanine) Methyltransferase Activity Transferase Activity TRNA (guanine(18)-2'-O)-methyltransferase Activity
	Biological Process	Protein Folding Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Insulin Processing Extracellular Matrix Organization Protein Folding In Endoplasmic Reticulum Glucose Homeostasis Cell Redox Homeostasis Protein Maturation	Regulation Of Transcription By RNA Polymerase II RNA Processing TRNA Processing TRNA Methylation Methylation
Pathways		Insulin processing
Drugs		1-Ethyl-Pyrrolidine-2,5-Dione Flavin adenine dinucleotide
Diseases
GWAS			Cognitive test performance ( 17903297) Psoriasis ( 25854761) White matter hyperintensity volume ( 33293549) White matter hyperintensity volume (adjusted for hypertension) ( 33293549) White matter hyperintensity volume x hypertension interaction (2df) ( 33293549)
Interacting Genes		4 interacting genes: BRCA1 ERP44 OGT P4HB	3 interacting genes: ERG RNF10 SREK1
Entrez ID		56605	6894
HPRD ID		13279	05445
Ensembl ID		ENSG00000086619	ENSG00000059588
Uniprot IDs		Q86YB8	Q13395
PDB IDs			2HA8
Enriched GO Terms of Interacting Partners?			Mitochondrial Electron Transport, Succinate To Ubiquinone Respiratory Chain Complex II (succinate Dehydrogenase) Succinate Dehydrogenase (quinone) Activity 3 Iron, 4 Sulfur Cluster Binding Succinate Metabolic Process Ubiquinone Binding Ribosome-associated Ubiquitin-dependent Protein Catabolic Process Postsynapse To Nucleus Signaling Pathway Negative Regulation Of Schwann Cell Proliferation Extrinsic Component Of Postsynaptic Density Membrane Disulfide Oxidoreductase Activity Insulin Processing Thiol Oxidase Activity
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