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RELN and PCDHA6
Number of citations of the paper that reports this interaction (PMID
10612399
)
24
Data Source:
HPRD
(in vitro)
RELN
PCDHA6
Gene Name
reelin
protocadherin alpha 6
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Proteinaceous Extracellular Matrix
Extracellular Space
Cytoplasm
Dendrite
Extracellular Region
Integral Component Of Plasma Membrane
Molecular Function
Protein Serine/threonine/tyrosine Kinase Activity
Serine-type Peptidase Activity
Metal Ion Binding
Lipoprotein Particle Receptor Binding
Very-low-density Lipoprotein Particle Receptor Binding
Calcium Ion Binding
Biological Process
Cell Morphogenesis Involved In Differentiation
Neuron Migration
Proteolysis
Cell Adhesion
Axon Guidance
Central Nervous System Development
Brain Development
Long-term Memory
Associative Learning
Glial Cell Differentiation
Positive Regulation Of Neuron Projection Development
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Dendrite Development
Peptidyl-tyrosine Phosphorylation
Spinal Cord Patterning
Ventral Spinal Cord Development
Hippocampus Development
Cerebral Cortex Tangential Migration
Layer Formation In Cerebral Cortex
Positive Regulation Of TOR Signaling
Positive Regulation Of CREB Transcription Factor Activity
Reelin-mediated Signaling Pathway
Positive Regulation Of Protein Kinase Activity
Response To Pain
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Regulation Of Behavior
Regulation Of Synaptic Transmission
Positive Regulation Of Small GTPase Mediated Signal Transduction
Positive Regulation Of Synaptic Transmission, Glutamatergic
Positive Regulation Of Dendritic Spine Morphogenesis
Positive Regulation Of Protein Tyrosine Kinase Activity
Positive Regulation Of Synapse Maturation
N-methyl-D-aspartate Receptor Clustering
Postsynaptic Density Protein 95 Clustering
Receptor Localization To Synapse
Lateral Motor Column Neuron Migration
Positive Regulation Of Long-term Synaptic Potentiation
Positive Regulation Of Lateral Motor Column Neuron Migration
Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity
Positive Regulation Of Excitatory Postsynaptic Membrane Potential
Positive Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity
Cell Adhesion
Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
Nervous System Development
Pathways
Drugs
Diseases
GWAS
Alzheimer's disease (
20452100
)
Multiple sclerosis (age of onset) (
19010793
)
Otosclerosis (
19230858
)
Schizophrenia (
18282107
)
Protein-Protein Interactions
6 interactors:
DAB1
LRP8
PCDHA4
PCDHA6
SQSTM1
VLDLR
1 interactors:
RELN
Entrez ID
5649
56142
HPRD ID
02742
07324
Ensembl ID
ENSG00000189056
ENSG00000081842
Uniprot IDs
P78509
Q9UN73
PDB IDs
Enriched GO Terms of Interacting Partners
?
Reelin-mediated Signaling Pathway
Positive Regulation Of Protein Phosphorylation
Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules
Cell-cell Adhesion
Positive Regulation Of Phosphorylation
Positive Regulation Of Protein Modification Process
Nervous System Development
Positive Regulation Of Neuron Differentiation
Regulation Of Protein Phosphorylation
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Neuron Projection Development
Ventral Spinal Cord Development
Positive Regulation Of Dendrite Development
Positive Regulation Of Neurogenesis
Positive Regulation Of Protein Metabolic Process
Cerebral Cortex Radially Oriented Cell Migration
Regulation Of Phosphorylation
Positive Regulation Of Protein Kinase Activity
Developmental Process
Regulation Of Cell Projection Organization
Positive Regulation Of Kinase Activity
Positive Regulation Of Cell Development
Regulation Of Phosphorus Metabolic Process
Cerebral Cortex Cell Migration
Regulation Of Neuron Differentiation
Positive Regulation Of Transferase Activity
Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration
Ammon Gyrus Development
Telencephalon Cell Migration
Forebrain Cell Migration
Regulation Of Dendrite Development
Spinal Cord Development
Regulation Of Neurogenesis
Cerebellum Structural Organization
Regulation Of Protein Kinase Activity
Regulation Of Cellular Protein Metabolic Process
Cerebral Cortex Development
Regulation Of Kinase Activity
Lateral Motor Column Neuron Migration
Very-low-density Lipoprotein Particle Clearance
Glycoprotein Transport
Regulation Of Cell Development
Positive Regulation Of Cell Differentiation
System Development
Regulation Of Protein Metabolic Process
Spinal Cord Motor Neuron Migration
Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
Pallium Development
Radial Glia Guided Migration Of Purkinje Cell
Central Nervous System Development
Positive Regulation Of Lateral Motor Column Neuron Migration
Positive Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity
Positive Regulation Of Glutamate Receptor Signaling Pathway
Positive Regulation Of Long-term Synaptic Potentiation
Lateral Motor Column Neuron Migration
Spinal Cord Motor Neuron Migration
N-methyl-D-aspartate Receptor Clustering
Reelin-mediated Signaling Pathway
Regulation Of Long-term Synaptic Potentiation
Receptor Localization To Synapse
Postsynaptic Density Protein 95 Clustering
Cerebral Cortex Tangential Migration
Positive Regulation Of Neuron Migration
Positive Regulation Of Dendritic Spine Morphogenesis
Positive Regulation Of Synapse Maturation
Positive Regulation Of CREB Transcription Factor Activity
Protein Localization To Synapse
Regulation Of Synapse Maturation
Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity
Positive Regulation Of TOR Signaling
Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity
Positive Regulation Of Synaptic Transmission, Glutamatergic
Positive Regulation Of Dendritic Spine Development
Postsynaptic Membrane Organization
Regulation Of Dendritic Spine Morphogenesis
Spinal Cord Patterning
Positive Regulation Of Excitatory Postsynaptic Membrane Potential
Positive Regulation Of Protein Tyrosine Kinase Activity
Positive Regulation Of Dendrite Morphogenesis
Response To Pain
Layer Formation In Cerebral Cortex
Positive Regulation Of Receptor Activity
Positive Regulation Of Membrane Potential
Long-term Memory
Cerebral Cortex Radial Glia Guided Migration
Regulation Of Dendritic Spine Development
Positive Regulation Of Ion Transmembrane Transporter Activity
Receptor Clustering
Regulation Of Neuron Migration
Positive Regulation Of Transporter Activity
Ventral Spinal Cord Development
Positive Regulation Of Dendrite Development
Regulation Of TOR Signaling
Regulation Of Protein Tyrosine Kinase Activity
Positive Regulation Of Small GTPase Mediated Signal Transduction
Cerebral Cortex Radially Oriented Cell Migration
Regulation Of Synaptic Transmission, Glutamatergic
Glial Cell Migration
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Regulation Of Dendrite Morphogenesis
Tagcloud
?
ancestral
ap2
boxes
caat
codes
conform
duplication
exons
flanking
gt
hsp40
intron
introns
lacks
microexon
minigene
polyadenylation
positions
pseudogene
rdj1
reeler
reelin
repeats
rule
splice
successive
symbol
tandemly
tata
Tagcloud (Difference)
?
ancestral
ap2
boxes
caat
codes
conform
duplication
exons
flanking
gt
hsp40
intron
introns
lacks
microexon
minigene
polyadenylation
positions
pseudogene
rdj1
reeler
reelin
repeats
rule
splice
successive
symbol
tandemly
tata
Tagcloud (Intersection)
?