PRMT8 and CEP162

Number of citations of the paper that reports this interaction (PubMedID 23455924)
0

Data Source:
BioGRID (two hybrid)

		PRMT8	CEP162
Description		protein arginine methyltransferase 8	centrosomal protein 162
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Centriole Spindle Cytosol Cytoskeleton Microtubule Axonemal Microtubule Centriolar Satellite Ciliary Basal Body
	Molecular Function	Protein Binding Methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity Protein-arginine N-methyltransferase Activity Transferase Activity Enzyme Binding Protein-arginine Omega-N Monomethyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone Methyltransferase Activity Identical Protein Binding Protein Homodimerization Activity Histone H4 Methyltransferase Activity S-adenosyl-L-methionine Binding	Protein Binding
	Biological Process	Chromatin Remodeling Regulation Of DNA-templated Transcription Protein Methylation Peptidyl-arginine Methylation Methylation Protein Homooligomerization Regulation Of Modification Of Postsynaptic Actin Cytoskeleton	Cell Projection Organization Cilium Assembly
Pathways			Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS		Cardiac Troponin-T levels ( 31014085) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Gut microbiota (bacterial taxa) ( 27723756) HDL cholesterol ( 19060911)	Diabetic retinopathy in type 2 diabetes ( 25364816)
Interacting Genes		20 interacting genes: CARM1 CEP162 COIL DCAF8 FBL FYN GPATCH2L H4C1 KRTAP6-3 OFCC1 PIK3R1 PLCG1 PPARA PRMT1 PRMT2 SERBP1 TNPO2 UBL5 VHL ZNF451	7 interacting genes: CPNE4 KDM1A MTDH PRMT1 PRMT8 SPP1 YEATS4
Entrez ID		56341	22832
HPRD ID		11029	10796
Ensembl ID		ENSG00000111218	ENSG00000135315
Uniprot IDs		Q59GT2 Q9NR22	Q5TB80
PDB IDs		4X41 5DST
Enriched GO Terms of Interacting Partners?		Protein-arginine Omega-N Asymmetric Methyltransferase Activity Protein-arginine N-methyltransferase Activity Histone Methyltransferase Activity Neurotrophin TRKA Receptor Binding Methyltransferase Activity Cajal Body Nucleus Negative Regulation Of Inflammatory Response Methylation Negative Regulation Of Developmental Process Protein Methyltransferase Activity Phosphatidylinositol 3-kinase Binding Negative Regulation Of Reactive Oxygen Species Biosynthetic Process Negative Regulation Of Myeloid Cell Differentiation Negative Regulation Of Megakaryocyte Differentiation Macromolecule Methylation Negative Regulation Of Defense Response Protein Modification Process Nucleoplasm Chromatin Remodeling U6 SnRNA 2'-O-ribose Methyltransferase Activity Regulation Of Apoptotic Process Regulation Of Reactive Oxygen Species Biosynthetic Process Negative Regulation Of Inflammatory Response To Antigenic Stimulus Cellular Response To Glycine Negative Regulation Of Reactive Oxygen Species Metabolic Process Response To Singlet Oxygen Protein Methylation Histone H3R8 Methyltransferase Activity GATOR1 Complex Binding Negative Regulation Of Cell Differentiation Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Megakaryocyte Differentiation Positive Regulation Of Transformation Of Host Cell By Virus Regulation Of Developmental Process Regulation Of Programmed Cell Death DNA-binding Transcription Factor Binding Regulation Of Inflammatory Response	Protein-arginine Omega-N Monomethyltransferase Activity Peptidyl-arginine Methylation Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone H4 Methyltransferase Activity Regulation Of Double-strand Break Repair Via Homologous Recombination Protein-arginine N-methyltransferase Activity Regulation Of DNA Recombination Regulation Of Double-strand Break Repair Regulation Of Cellular Response To Stress S-adenosyl-L-methionine Binding Chromatin Remodeling Histone Methyltransferase Activity Protein Methylation Regulation Of DNA Repair Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Chromatin Organization Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Enzyme Binding Positive Regulation Of DNA Recombination Regulation Of RNA Metabolic Process GATOR1 Complex Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Double-strand Break Repair Regulation Of DNA Metabolic Process Positive Regulation Of Estradiol Secretion Histone H3K18ac Reader Activity Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Macromolecule Methylation Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Estradiol Secretion Histone H3K27ac Reader Activity Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of DNA Repair Regulation Of Multicellular Organismal Development Positive Regulation Of Biosynthetic Process Response To Nutrient N-methyltransferase Activity Protein Demethylase Activity Histone H4R3 Methyltransferase Activity Methyltransferase Activity Positive Regulation Of Hemoglobin Biosynthetic Process Androgen Catabolic Process MRF Binding Regulation Of Hemoglobin Biosynthetic Process Mitogen-activated Protein Kinase P38 Binding Response To Methionine
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?