DNAH7 and CSTF3

		DNAH7	CSTF3
Description		dynein axonemal heavy chain 7	cleavage stimulation factor subunit 3
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GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Axonemal Dynein Complex Microtubule Cilium Dynein Complex Motile Cilium Inner Dynein Arm Cell Projection 9+2 Motile Cilium	Nucleus Nucleoplasm MRNA Cleavage Stimulating Factor Complex
	Molecular Function	Nucleotide Binding Microtubule Motor Activity Calcium Ion Binding ATP Binding Minus-end-directed Microtubule Motor Activity Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding	RNA Binding MRNA Binding Protein Binding
	Biological Process	Cilium Movement Microtubule-based Movement Inner Dynein Arm Assembly Cilium-dependent Cell Motility Cilium Movement Involved In Cell Motility	RNA Processing MRNA Processing RNA 3'-end Processing MRNA 3'-end Processing Co-transcriptional MRNA 3'-end Processing, Cleavage And Polyadenylation Pathway
Pathways			mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS		Diastolic blood pressure ( 31469255)	Anger ( 24489884) Non-response to citalopram or escitalopram and depression ( 27622933)
Interacting Genes		1 interacting genes: UBC	15 interacting genes: CEBPA CSTF1 CSTF2 DLGAP1-AS2 MIR128-2 MIR138-2 MIR15B MIR19A MIR19B1 MIR21 MIR92A2 MIRLET7A3 MIRLET7F2 MIRLET7G MIRLET7I
Entrez ID		56171	1479
HPRD ID		10914	02651
Ensembl ID		ENSG00000118997	ENSG00000176102
Uniprot IDs		Q8WXX0	Q12996
PDB IDs		6RZA 8J07	6B3X 6URO 7ZY4
Enriched GO Terms of Interacting Partners?			RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Extracellular Vesicle Negative Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Regulation Of Inflammatory Response Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Cardiac Epithelial To Mesenchymal Transition Positive Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Striated Muscle Cell Apoptotic Process Negative Regulation Of Defense Response MRNA 3'-UTR Binding Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Matrix Metallopeptidase Secretion Negative Regulation Of Cell Migration Regulation Of Muscle Cell Differentiation Regulation Of Cardiac Muscle Cell Apoptotic Process Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Muscle Cell Apoptotic Process Negative Regulation Of Locomotion Negative Regulation Of Inflammatory Response Negative Regulation Of Translation Negative Regulation Of Cell Differentiation Regulation Of Extracellular Matrix Organization Negative Regulation Of Cellular Response To Transforming Growth Factor Beta Stimulus Negative Regulation Of Extracellular Matrix Assembly Negative Regulation Of Endothelial Cell Migration Regulation Of Matrix Metallopeptidase Secretion Cellular Response To Bacterial Lipopeptide Regulation Of Cardiac Muscle Hypertrophy HMG Box Domain Binding Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation Response To Bacterial Lipoprotein Negative Regulation Of Fibroblast Migration Positive Regulation Of Muscle Cell Differentiation Regulation Of Defense Response
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