BCAP29 and PDXDC1

Number of citations of the paper that reports this interaction (PubMedID 11591653)
29

Data Source:
HPRD (in vivo)

		BCAP29	PDXDC1
Description		B cell receptor associated protein 29	pyridoxal dependent decarboxylase domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Golgi Apparatus Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Lyase Activity Carbon-carbon Lyase Activity Carboxy-lyase Activity Pyridoxal Phosphate Binding Cadherin Binding
	Biological Process	Osteoblast Differentiation Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Apoptotic Process Protein Transport Vesicle-mediated Transport Protein Localization To Endoplasmic Reticulum Exit Site	Carboxylic Acid Metabolic Process
Pathways
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778 32469254) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Age at first sexual intercourse ( 34211149) Apolipoprotein A1 levels ( 32203549) Body mass index ( 28892062 29273807 25673413) Body mass index and triglycerides (pairwise) ( 33619380) Cholesteryl ester levels ( 31551469) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Copper levels ( 26025379) Fatty acid desaturase activity (serum) ( 30453627) Fruit consumption ( 32066663) HDL cholesterol levels ( 32203549) Height ( 31562340 20189936) Hip circumference ( 25673412) Metabolic syndrome ( 31589552) Metabolic traits ( 21886157) Phospholipid levels (plasma) ( 22359512) Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid) ( 21829377) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311) Serum metabolite levels ( 33031748) Triglyceride levels ( 28334899 32154731 32203549) Triglyceride levels x long total sleep time interaction (2df test) ( 31719535) Triglycerides ( 24097068) Waist circumference ( 28552196) Weight ( 28552196)
Interacting Genes		5 interacting genes: BCAP31 CREB3 DRD2 IGHD PDXDC1	2 interacting genes: BCAP29 HTRA2
Entrez ID		55973	23042
HPRD ID		16541	13789
Ensembl ID		ENSG00000075790	ENSG00000179889
Uniprot IDs		E9PAJ1 Q9UHQ4	B4DHL7 Q6P996 Q86XE2
PDB IDs		4W7Y 4W7Z 4W80
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Synaptic Transmission, Glutamatergic Response To Histamine Regulation Of Synapse Structural Plasticity Dopamine Binding Regulation Of Renal Sodium Excretion Dopamine Neurotransmitter Receptor Activity Cerebral Cortex GABAergic Interneuron Migration Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Circadian Sleep/wake Cycle, Sleep Regulation Of Dopamine Receptor Signaling Pathway Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Golgi Membrane G Protein-coupled Receptor Complex Catecholamine Uptake Dopamine Uptake Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go Adenohypophysis Development Negative Regulation Of Dephosphorylation Response To Inactivity Positive Regulation Of Renal Sodium Excretion Positive Regulation Of Glial Cell-derived Neurotrophic Factor Production Negative Regulation Of Neuron Migration Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Hyaloid Vascular Plexus Regression Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Orbitofrontal Cortex Development Neuron-neuron Synaptic Transmission Interneuron Migration From The Subpallium To The Cortex Branching Morphogenesis Of A Nerve Negative Regulation Of Dopamine Secretion Peristalsis Positive Regulation Of Growth Hormone Secretion Positive Regulation Of Neurotransmitter Uptake Regulation Of Dopamine Uptake Involved In Synaptic Transmission Regulation Of Cellular Response To Stress Heterotrimeric G-protein Binding Regulation Of Locomotion Involved In Locomotory Behavior Positive Regulation Of Transport Positive Regulation Of Urine Volume Behavioral Response To Ethanol Negative Regulation Of Dopamine Receptor Signaling Pathway Nervous System Process Involved In Regulation Of Systemic Arterial Blood Pressure Phospholipase C-activating Dopamine Receptor Signaling Pathway Drinking Behavior IgD Immunoglobulin Complex Immunoglobulin Complex, Circulating Protein Localization To Endoplasmic Reticulum Exit Site Response To Endoplasmic Reticulum Stress Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Retrograde Protein Transport, ER To Cytosol	Pentacyclic Triterpenoid Metabolic Process Negative Regulation Of Type 2 Mitophagy Response To Herbicide Mitochondrial Protein Catabolic Process Ubiquitin Ligase Inhibitor Activity CD40 Receptor Complex Serine-type Endopeptidase Complex Negative Regulation Of Mitophagy Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Protein Localization To Endoplasmic Reticulum Exit Site Positive Regulation Of Execution Phase Of Apoptosis Cell Death Apoptotic Process Cellular Response To Interferon-beta Execution Phase Of Apoptosis Protein Autoprocessing Programmed Cell Death Protein Serine/threonine Kinase Inhibitor Activity Protein Localization To Endoplasmic Reticulum Walking Behavior Adult Walking Behavior Endoplasmic Reticulum Membrane Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Establishment Of Protein Localization To Mitochondrion Response To Interferon-beta Negative Regulation Of Macroautophagy Positive Regulation Of Protein Targeting To Mitochondrion Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Protein Targeting To Mitochondrion Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Mitophagy Regulation Of Autophagy Of Mitochondrion Cellular Response To Heat Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Endoplasmic Reticulum Regulation Of Multicellular Organism Growth Cellular Response To Retinoic Acid Forebrain Development Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Mitochondrial Intermembrane Space Adult Locomotory Behavior Response To Heat Terpenoid Metabolic Process Ceramide Metabolic Process Response To Retinoic Acid Isoprenoid Metabolic Process Response To Toxic Substance Negative Regulation Of Autophagy Cytoplasmic Side Of Plasma Membrane Neuron Apoptotic Process
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