PDXDC1

Description		pyridoxal dependent decarboxylase domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Intracellular Membrane-bounded Organelle
	Molecular Function	Lyase Activity Carbon-carbon Lyase Activity Carboxy-lyase Activity Pyridoxal Phosphate Binding Cadherin Binding
	Biological Process	Carboxylic Acid Metabolic Process
Pathways
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Apolipoprotein A1 levels ( 32203549) Body mass index ( 28892062 29273807 25673413) Body mass index and triglycerides (pairwise) ( 33619380) Cholesteryl ester levels ( 31551469) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Copper levels ( 26025379) Fatty acid desaturase activity (serum) ( 30453627) Fruit consumption ( 32066663) HDL cholesterol levels ( 32203549) Height ( 31562340 20189936) Hip circumference ( 25673412) Metabolic syndrome ( 31589552) Metabolic traits ( 21886157) Phospholipid levels (plasma) ( 22359512) Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid) ( 21829377) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311) Serum metabolite levels ( 33031748) Triglyceride levels ( 28334899 32154731 32203549) Triglyceride levels x long total sleep time interaction (2df test) ( 31719535) Triglycerides ( 24097068) Waist circumference ( 28552196) Weight ( 28552196)
Interacting Genes		2 interacting genes: BCAP29 HTRA2
Entrez ID		23042
HPRD ID		13789
Ensembl ID		ENSG00000179889
Uniprot IDs		B4DHL7 Q6P996 Q86XE2
PDB IDs
Enriched GO Terms of Interacting Partners?		Pentacyclic Triterpenoid Metabolic Process Negative Regulation Of Type 2 Mitophagy Response To Herbicide Mitochondrial Protein Catabolic Process Ubiquitin Ligase Inhibitor Activity CD40 Receptor Complex Serine-type Endopeptidase Complex Negative Regulation Of Mitophagy Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Protein Localization To Endoplasmic Reticulum Exit Site Positive Regulation Of Execution Phase Of Apoptosis Cell Death Apoptotic Process Cellular Response To Interferon-beta Execution Phase Of Apoptosis Protein Autoprocessing Programmed Cell Death Protein Serine/threonine Kinase Inhibitor Activity Protein Localization To Endoplasmic Reticulum Walking Behavior Adult Walking Behavior Endoplasmic Reticulum Membrane Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Establishment Of Protein Localization To Mitochondrion Response To Interferon-beta Negative Regulation Of Macroautophagy Positive Regulation Of Protein Targeting To Mitochondrion Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Protein Targeting To Mitochondrion Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Mitophagy Regulation Of Autophagy Of Mitochondrion Cellular Response To Heat Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Endoplasmic Reticulum Regulation Of Multicellular Organism Growth Cellular Response To Retinoic Acid Forebrain Development Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Mitochondrial Intermembrane Space Adult Locomotory Behavior Response To Heat Terpenoid Metabolic Process Ceramide Metabolic Process Response To Retinoic Acid Isoprenoid Metabolic Process Response To Toxic Substance Negative Regulation Of Autophagy Cytoplasmic Side Of Plasma Membrane Neuron Apoptotic Process
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