TENM1 and NUBP1

Number of citations of the paper that reports this interaction (PubMedID 25648896)
70

Data Source:
BioGRID (two hybrid)

		TENM1	NUBP1
Description		teneurin transmembrane protein 1	NUBP iron-sulfur cluster assembly factor 1, cytosolic
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cytoskeleton Plasma Membrane Membrane Nuclear Matrix Nuclear Speck Neuron Projection Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Golgi Apparatus Centrosome Centriole Microtubule Organizing Center Cytosol Cytoskeleton Cilium Cell Projection
	Molecular Function	Heparin Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity Cell Adhesion Molecule Binding	Nucleotide Binding Protein Binding ATP Binding Metal Ion Binding Iron-sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding ATP-dependent FeS Chaperone Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase III Immune Response Signal Transduction Neuropeptide Signaling Pathway Nervous System Development Negative Regulation Of Cell Population Proliferation Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of MAP Kinase Activity Neuron Development Positive Regulation Of Filopodium Assembly Positive Regulation Of Intracellular Protein Transport	Regulation Of Cell Growth Intracellular Iron Ion Homeostasis Negative Regulation Of Centrosome Duplication Iron-sulfur Cluster Assembly Cell Projection Organization Centrosome Localization Protein Localization To Cell Cortex
Pathways			Cytosolic iron-sulfur cluster assembly
Drugs
Diseases
GWAS			Cerebrospinal AB1-42 levels in normal cognition ( 29274321)
Interacting Genes		12 interacting genes: APBB1 BEX1 CSNK2B FIBP MACF1 MBD1 NUBP1 PICALM POLR2J PTPN12 RACK1 SORBS1	3 interacting genes: NDN SPRY2 TENM1
Entrez ID		10178	4682
HPRD ID		06669	02611
Ensembl ID		ENSG00000009694	ENSG00000103274
Uniprot IDs		B7ZMH4 Q9UKZ4	P53384
PDB IDs
Enriched GO Terms of Interacting Partners?		Low-density Lipoprotein Particle Receptor Binding Nucleus Regulation Of Protein Localization To Cell Periphery Regulation Of Protein Localization To Plasma Membrane Regulation Of Protein Localization To Membrane	Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Peptidyl-serine Phosphorylation Neuron Development Developmental Growth Involved In Morphogenesis Cell Projection System Development Positive Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Ubiquitin-protein Transferase Inhibitor Activity Lung Growth Microtubule End Negative Regulation Of Lens Fiber Cell Differentiation Ionotropic Glutamate Receptor Complex Positive Regulation Of Phosphate Metabolic Process Bud Elongation Involved In Lung Branching Regulation Of Lens Fiber Cell Differentiation Respiratory System Development Developmental Growth Positive Regulation Of Protein Modification Process Regulation Of Protein Phosphorylation Regulation Of Neurotrophin TRK Receptor Signaling Pathway Branch Elongation Of An Epithelium Dendritic Spine Membrane Neurotrophin TRK Receptor Signaling Pathway Regulation Of Phosphorylation Negative Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Regulation Of Short-term Neuronal Synaptic Plasticity Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of MAPK Cascade Axis Elongation Negative Regulation Of Cellular Response To Vascular Endothelial Growth Factor Stimulus Sensory Perception Axonal Fasciculation Neuron Projection Fasciculation Genomic Imprinting Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Respiratory Gaseous Exchange By Respiratory System Epigenetic Programming Of Gene Expression Neurotrophin Signaling Pathway Enzyme-linked Receptor Protein Signaling Pathway Glial Cell Migration Respiratory System Process Gamma-tubulin Binding Positive Regulation Of MAP Kinase Activity Regulation Of Transcription By RNA Polymerase III Regulation Of Phosphorus Metabolic Process Regulation Of Protein Modification Process Positive Regulation Of Filopodium Assembly Regulation Of MAPK Cascade
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