CENPN and DNAAF19

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CENPN	DNAAF19
Description		centromere protein N	dynein axonemal assembly factor 19
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Inner Kinetochore Nucleus Nucleoplasm Chromosome Cytosol	Extracellular Region Cytoplasm Cilium Axoneme Motile Cilium Outer Dynein Arm Cell Projection
	Molecular Function	Protein Binding	Protein Binding Protein Homodimerization Activity
	Biological Process	Chromosome Segregation CENP-A Containing Chromatin Assembly	Heart Looping Cilium Movement Epithelial Cilium Movement Involved In Extracellular Fluid Movement Determination Of Left/right Symmetry Cell Projection Organization Outer Dynein Arm Assembly Inner Dynein Arm Assembly Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Axonemal Dynein Complex Assembly Determination Of Digestive Tract Left/right Asymmetry
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		4 interacting genes: ALKBH7 DNAAF19 OSGIN1 TSSK3	17 interacting genes: CENPN GRIPAP1 HGS MEOX1 MEOX2 PAX6 PICK1 PKN1 PLAAT1 PNMA6A PRKAR1B R3HCC1L RCN3 RUVBL2 SUOX USHBP1 VAC14
Entrez ID		55839	388389
HPRD ID		12528	14200
Ensembl ID		ENSG00000166451	ENSG00000167131
Uniprot IDs		Q96H22	Q8IW40
PDB IDs		6BUZ 6C0W 6EQT 6MUO 6MUP 7PKN 7QOO 7R5S 7R5V 7U46 7U47 7U4D 7XHN 7XHO 7YWX 7YYH
Enriched GO Terms of Interacting Partners?			Somite Specification Segment Specification HMG Box Domain Binding Somite Development Regulation Of Vesicle-mediated Transport RNA Polymerase II Core Promoter Sequence-specific DNA Binding
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