UGGT2 and DZIP1

		UGGT2	DZIP1
Description		UDP-glucose glycoprotein glucosyltransferase 2	DAZ interacting zinc finger protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum-Golgi Intermediate Compartment Protein-containing Complex Endoplasmic Reticulum Quality Control Compartment	Nucleus Nucleoplasm Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Cilium Nuclear Speck Centriolar Satellite Ciliary Basal Body Cell Projection Ciliary Transition Fiber Ciliary Base
	Molecular Function	UDP-glucose:glycoprotein Glucosyltransferase Activity Protein Binding Transferase Activity Glycosyltransferase Activity Unfolded Protein Binding	Protein Binding Zinc Ion Binding Metal Ion Binding Molecular Adaptor Activity BBSome Binding
	Biological Process	Protein Glycosylation Protein N-linked Glycosylation Via Asparagine UDP-glucosylation Endoplasmic Reticulum Mannose Trimming	Smoothened Signaling Pathway Germ Cell Development Spermatogenesis Heart Development Cell Projection Organization Cell Differentiation Ciliary Basal Body Organization Protein Localization To Organelle Cilium Organization Establishment Of Protein Localization Positive Regulation Of Cilium Assembly Establishment Of Localization In Cell Cilium Assembly Protein Localization To Cilium Sperm Flagellum Assembly Protein-containing Complex Localization To Centriolar Satellite Positive Regulation Of Protein Localization To Cilium
Pathways		ER Quality Control Compartment (ERQC)	Hedgehog 'on' state
Drugs
Diseases
GWAS		Body mass index ( 26426971) Femur bone mineral density x serum urate levels interaction ( 34046847) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)	Glomerular filtration rate (cystatin C) ( 26831199) Response to statins (LDL cholesterol change) ( 25350695)
Interacting Genes		3 interacting genes: APP APPBP2 SELENOF	12 interacting genes: DAZ1 DAZ4 LUC7L2 MECOM MOS OPTN PPP1R18 PPP2R5A PRPF40A RNF10 TIAM1 TNS2
Entrez ID		55757	22873
HPRD ID		12065	16363
Ensembl ID		ENSG00000102595	ENSG00000134874
Uniprot IDs		Q05D90 Q9NYU1	B3KSP1 Q86YF9
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling 'de Novo' Post-translational Protein Folding Ciliary Basal Body Organization BBSome Binding Protein-containing Complex Localization To Centriolar Satellite DTDP-glucose 4,6-dehydratase Activity Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Thioredoxin Peroxidase Activity Positive Regulation Of Protein Localization To Cilium Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Ciliary Transition Fiber Peptidase Activator Activity Cellular Response To Manganese Ion Selenium Binding Endoplasmic Reticulum Lumen 'de Novo' Protein Folding Regulation Of Protein Localization To Cilium Antifungal Humoral Response Nuclear Envelope Lumen	Translation Activator Activity 3'-UTR-mediated MRNA Stabilization Kinase Binding U2-type Prespliceosome U1 SnRNP
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