UGGT2

Gene Name		UDP-glucose glycoprotein glucosyltransferase 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Lumen Endoplasmic Reticulum-Golgi Intermediate Compartment
	Molecular Function	UDP-glucose:glycoprotein Glucosyltransferase Activity
	Biological Process	Protein Folding Protein N-linked Glycosylation Via Asparagine Post-translational Protein Modification Cellular Protein Metabolic Process UDP-glucosylation
Pathways		Diseases of glycosylation Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective ALG1 causes ALG1-CDG (CDG-1k) Defective MOGS causes MOGS-CDG (CDG-2b) Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 N-glycan trimming in the ER and Calnexin/Calreticulin cycle Defective ALG11 causes ALG11-CDG (CDG-1p) Defective ALG2 causes ALG2-CDG (CDG-1i) Post-translational protein modification Defective ALG3 causes ALG3-CDG (CDG-1d) Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective ALG6 causes ALG6-CDG (CDG-1c) Defective RFT1 causes RFT1-CDG (CDG-1n) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) ER Quality Control Compartment (ERQC) Diseases associated with N-glycosylation of proteins Calnexin/calreticulin cycle
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: APP APPBP2 SEP15
Entrez ID		55757
HPRD ID		12065
Ensembl ID		ENSG00000102595
Uniprot IDs		Q05D90 Q8N5K0 Q9NYU1
PDB IDs
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling
Tagcloud ?		aglycons analytical called chemistry correctly folded folding glucosylates glucosylating glycans glycoproteins homogeneous hydrophobic intentionally introduced isoform mannose misfolded naturally optimum performing precise recognizes sensor stemmed strengthened substrates synthetic uggt1