SEPT11 and SEPT5

Number of citations of the paper that reports this interaction (PMID 22939629)
44

Data Source:
BioGRID (two hybrid, biochemical)

		SEPT11	SEPT5
Gene Name		septin 11	septin 5
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Stress Fiber Cytoplasm Cell Junction Axon Dendritic Spine Synapse Extracellular Vesicular Exosome	Cytoskeleton Plasma Membrane Cell Cortex Synaptic Vesicle Terminal Bouton
	Molecular Function	Protein Binding GTP Binding	GTPase Activity Structural Molecule Activity Protein Binding GTP Binding
	Biological Process	Cell Cycle Protein Heterooligomerization Cell Division	Cytokinesis Metabolic Process Synaptic Vesicle Targeting Regulation Of Exocytosis Regulation Of Synaptic Vesicle Exocytosis
Pathways
Drugs
Diseases
GWAS		Waist-to-hip circumference ratio (interaction) ( 23192594)	DNA methylation (parent-of-origin) ( 23725790)
Protein-Protein Interactions		3 interactors: SEPT5 SEPT7 SEPT9	18 interactors: APP KAT7 LSM8 MAGEA2B MAPK6 MYOG PARK2 PFN2 SEPT1 SEPT10 SEPT11 SEPT2 SEPT4 SEPT6 SEPT7 SEPT8 STX1A STX4
Entrez ID		55752	5413
HPRD ID		08555	04100
Ensembl ID		ENSG00000138758	ENSG00000184702
Uniprot IDs		Q9NVA2	G3XAH0 Q99719
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Division Cytokinesis Protein Heterooligomerization Cell Cycle Regulation Of Embryonic Cell Shape Synaptic Vesicle Targeting Protein Oligomerization Regulation Of Synaptic Vesicle Exocytosis Regulation Of Synaptic Vesicle Transport Vesicle Targeting Protein Complex Assembly Cell Cycle Process Synaptic Vesicle Exocytosis Regulation Of Neurotransmitter Secretion Neurotransmitter Secretion Synaptic Vesicle Transport Regulation Of Embryonic Development	Cell Cycle Cell Division Regulation Of Synaptic Vesicle Transport Regulation Of Neurotransmitter Secretion Synaptic Vesicle Fusion To Presynaptic Membrane Regulation Of Synaptic Transmission Positive Regulation Of Protein Ubiquitination Regulation Of Vesicle-mediated Transport Regulation Of Neurotransmitter Levels Regulation Of Exocytosis Neurotransmitter Transport Regulation Of Synaptic Vesicle Exocytosis Regulation Of Insulin Secretion Regulation Of Protein Ubiquitination Regulation Of Peptide Hormone Secretion Vesicle Fusion Synaptic Vesicle Exocytosis Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Muscle Atrophy Positive Regulation Of Mitochondrial Fusion Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Hormone Secretion Positive Regulation Of Exocytosis Organelle Organization Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Secretion Organelle Fusion Sperm Mitochondrion Organization Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Synaptic Growth At Neuromuscular Junction Positive Regulation Of Eosinophil Degranulation Positive Regulation Of Protein Linear Polyubiquitination Regulation Of Embryonic Cell Shape Positive Regulation Of Protein Metabolic Process Vesicle Docking Cellular Component Assembly Exocytosis Regulation Of Cellular Component Organization Membrane Docking Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Dopamine Dopamine Uptake Involved In Synaptic Transmission Collateral Sprouting In Absence Of Injury Regulation Of Protein Localization Regulation Of Protein Secretion Cytokinesis Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Regulation Of L-glutamate Transport Neurotransmitter Secretion
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