SMEK1 and PPP4R2

Number of citations of the paper that reports this interaction (PMID 16085932)
43

Data Source:
BioGRID (pull down, biochemical)

		SMEK1	PPP4R2
Gene Name		SMEK homolog 1, suppressor of mek1 (Dictyostelium)	protein phosphatase 4, regulatory subunit 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Organizing Center Protein Phosphatase 4 Complex	Nucleus Nucleoplasm Cytoplasm Centrosome Protein Phosphatase 4 Complex
	Molecular Function		Protein Binding Protein Phosphatase Type 4 Regulator Activity Protein Binding, Bridging
	Biological Process	Protein Dephosphorylation Positive Regulation Of Gluconeogenesis	Hematopoietic Progenitor Cell Differentiation MRNA Processing Cellular Protein Modification Process RNA Splicing Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Catalytic Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: CASK MAPK14 PPP4R2	2 interactors: PPP4C SMEK1
Entrez ID		55671	151987
HPRD ID		11176	11453
Ensembl ID		ENSG00000100796	ENSG00000163605
Uniprot IDs		Q6IN85	Q9NY27
PDB IDs
Enriched GO Terms of Interacting Partners?		P38MAPK Cascade Positive Regulation Of Brown Fat Cell Differentiation Myoblast Differentiation Involved In Skeletal Muscle Regeneration Regulation Of Brown Fat Cell Differentiation Posttranscriptional Regulation Of Gene Expression 3'-UTR-mediated MRNA Stabilization Stress-induced Premature Senescence Negative Regulation Of Keratinocyte Proliferation Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Calcium Ion Import Regulation Of Body Fluid Levels Hemopoiesis Organ Development Positive Regulation Of Myoblast Differentiation Positive Regulation Of Myoblast Fusion Response To Muramyl Dipeptide Positive Regulation Of Erythrocyte Differentiation Cellular Protein Modification Process Immune System Development Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Regulation Of Myoblast Fusion Regulation Of Keratinocyte Proliferation Positive Regulation Of Transport Regulation Of Calcium Ion Import Cartilage Condensation Skeletal Muscle Tissue Regeneration MRNA Stabilization Regulation Of Double-strand Break Repair Cellular Senescence Positive Regulation Of Myotube Differentiation Calcium Ion Import Regulation Of Erythrocyte Differentiation Negative Regulation Of Cell-matrix Adhesion Lipopolysaccharide-mediated Signaling Pathway Regulation Of Myoblast Differentiation Cellular Response To Vascular Endothelial Growth Factor Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter System Development Osteoclast Differentiation Myoblast Differentiation Cellular Protein Metabolic Process Negative Regulation Of Cell-substrate Adhesion Tissue Regeneration Toll-like Receptor 5 Signaling Pathway Regulation Of MRNA Stability Toll-like Receptor 10 Signaling Pathway Positive Regulation Of Fat Cell Differentiation Regulation Of RNA Stability Nucleotide Phosphorylation Lactation	Dephosphorylation Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Gluconeogenesis Regulation Of Double-strand Break Repair Positive Regulation Of Glucose Metabolic Process NIK/NF-kappaB Signaling Regulation Of Gluconeogenesis Regulation Of DNA Repair Regulation Of DNA Recombination Regulation Of Glucose Metabolic Process Regulation Of Response To DNA Damage Stimulus Regulation Of Carbohydrate Metabolic Process Phosphate-containing Compound Metabolic Process
Tagcloud ?		4e activates actively additively arrests attempted bcl bp1 cascade cdk4 chemotherapeutic enhances gemcitabine initially luciferase modulators ovcar p16 p21 p27 p70s6k pdk1 pro promote promoted promotion suppresses tumorigenesis xl
Tagcloud (Difference) ?		4e activates actively additively arrests attempted bcl bp1 cascade cdk4 chemotherapeutic enhances gemcitabine initially luciferase modulators ovcar p16 p21 p27 p70s6k pdk1 pro promote promoted promotion suppresses tumorigenesis xl
Tagcloud (Intersection) ?