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G2E3 and WDR6
Number of citations of the paper that reports this interaction (PubMedID
16189514
)
0
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
G2E3
WDR6
Description
G2/M-phase specific E3 ubiquitin protein ligase
WD repeat domain 6
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleolus
Cytoplasm
Golgi Apparatus
Cytosol
Cytoplasm
Cytosol
Plasma Membrane
COP9 Signalosome
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Transferase Activity
Metal Ion Binding
Ubiquitin Protein Ligase Activity
TRNA Binding
RNA Binding
Protein Binding
Enzyme Regulator Activity
Biological Process
Apoptotic Process
Protein Ubiquitination
Wobble Position Ribose Methylation
TRNA Processing
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Autophagy
TRNA Methylation
G1 To G0 Transition
Pathways
RHOU GTPase cycle
RHOV GTPase cycle
RND3 GTPase cycle
RND2 GTPase cycle
RND1 GTPase cycle
Drugs
Diseases
GWAS
Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) (
26252872
)
Cognitive decline (age-related) (
28078323
)
Body fat distribution (leg fat ratio) (
30664634
)
Body fat distribution (trunk fat ratio) (
30664634
)
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Crohn's disease (
28067908
)
Inflammatory bowel disease (
28067908
)
Menarche (age at onset) (
25231870
)
Subcortical volume (min-P) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Ulcerative colitis (
28067908
)
Interacting Genes
4 interacting genes:
LST1
RPS15
TRIM54
WDR6
6 interacting genes:
BRCA1
CDC42EP4
G2E3
GRIP1
PTPN3
UBC
Entrez ID
55632
11180
HPRD ID
13851
06912
Ensembl ID
ENSG00000092140
ENSG00000178252
Uniprot IDs
B4DIF9
B4DL73
F5GX24
Q49AD9
Q7L622
A0A087X295
B3KRR8
B4E256
E9PDU5
Q9H9M3
Q9NNW5
PDB IDs
Enriched GO Terms of Interacting Partners
?
Regulation Of Fatty Acid Biosynthetic Process
Histone H2AK127 Ubiquitin Ligase Activity
Negative Regulation Of Lipid Biosynthetic Process
Histone H2AK129 Ubiquitin Ligase Activity
Intracellular Signal Transduction
Negative Regulation Of Lipid Metabolic Process
BRCA1-BARD1 Complex
Regulation Of Fatty Acid Metabolic Process
Response To Vitamin B3
SREBP-SCAP Complex
Negative Regulation Of Small Molecule Metabolic Process
Negative Regulation Of Centrosome Duplication
Negative Regulation Of Centriole Replication
BRCA1-A Complex
XY Body
BRCA1-B Complex
Post-translational Protein Modification
Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation
Lateral Element
Nuclear Ubiquitin Ligase Complex
Cellular Response To Indole-3-methanol
Regulation Of Anatomical Structure Morphogenesis
BRCA1-C Complex
Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Gamma-tubulin Ring Complex
Ubiquitin-modified Histone Reader Activity
Regulation Of Ketone Metabolic Process
Response To Indole-3-methanol
Negative Regulation Of Mitotic Cell Cycle
Ubiquitin Protein Ligase Binding
Protein Modification By Small Protein Conjugation
DNA Strand Resection Involved In Replication Fork Processing
Ubiquitin-protein Transferase Activity
Regulation Of Lipid Biosynthetic Process
Protein Ubiquitination
DNA Repair Complex
Random Inactivation Of X Chromosome
Negative Regulation Of Membrane Protein Ectodomain Proteolysis
Regulation Of Membrane Depolarization During Action Potential
Protein Tag Activity
Sterol Binding
Response To Sterol Depletion
Negative Regulation Of Cholesterol Biosynthetic Process
SREBP Signaling Pathway
Negative Regulation Of Cholesterol Metabolic Process
Cellular Response To Sterol Depletion
Endomembrane System
Endosome To Plasma Membrane Protein Transport
Establishment Of Protein Localization To Postsynaptic Membrane
Positive Regulation Of Neuron Projection Arborization
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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