G2E3 and WDR6

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		G2E3	WDR6
Gene Name		G2/M-phase specific E3 ubiquitin protein ligase	WD repeat domain 6
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Cytoplasm	Cytoplasm Plasma Membrane COP9 Signalosome
	Molecular Function	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity	Protein Binding Poly(A) RNA Binding
	Biological Process	Protein Polyubiquitination Blastocyst Development Apoptotic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway	Cell Cycle Arrest Negative Regulation Of Cell Proliferation Negative Regulation Of Autophagy
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: LST1 RPS15 WDR6	4 interactors: BRCA1 CDC42EP4 G2E3 PTPN3
Entrez ID		55632	11180
HPRD ID		13851	06912
Ensembl ID		ENSG00000092140	ENSG00000178252
Uniprot IDs		B4DIF9 F5GX24 Q7L622	B3KRR8 E9PDU5 Q9H9M3 Q9NNW5
PDB IDs
Enriched GO Terms of Interacting Partners?		Ribosomal Small Subunit Export From Nucleus Ribosomal Subunit Export From Nucleus Ribosomal Small Subunit Assembly Sodium-independent Organic Anion Transport Negative Regulation Of Cell Proliferation	Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Protein Polyubiquitination Positive Regulation Of Histone H3-K9 Acetylation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Liver Regeneration Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Membrane Depolarization During Action Potential Cellular Response To Indole-3-methanol Negative Regulation Of Centriole Replication Negative Regulation Of Membrane Protein Ectodomain Proteolysis Dosage Compensation By Inactivation Of X Chromosome Protein K6-linked Ubiquitination Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Regulation Of Histone H3-K9 Acetylation Positive Regulation Of Organelle Organization Regulation Of Centriole Replication Positive Regulation Of Histone H3-K4 Methylation Regulation Of Histone H4 Acetylation Negative Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Of Pseudopodium Assembly DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Negative Regulation Of Cell Cycle DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of Histone Methylation Regulation Of Cytoskeleton Organization Negative Regulation Of Centrosome Duplication Regulation Of DNA Methylation Negative Regulation Of Histone Acetylation Positive Regulation Of Histone Acetylation Negative Regulation Of Peptidyl-lysine Acetylation Regulation Of Histone H3-K4 Methylation Protein Ubiquitination Negative Regulation Of Protein Acetylation Positive Regulation Of Peptidyl-lysine Acetylation Postreplication Repair Positive Regulation Of Protein Acetylation Protein Modification By Small Protein Conjugation Regulation Of Transcription From RNA Polymerase III Promoter Negative Regulation Of Fatty Acid Metabolic Process Regulation Of Gene Expression By Genetic Imprinting Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Sodium Ion Transmembrane Transporter Activity Genetic Imprinting Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Vascular Endothelial Growth Factor Production G2 DNA Damage Checkpoint
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?