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MED29 and MED1
Number of citations of the paper that reports this interaction (PMID
22939629
)
44
Data Source:
BioGRID
(pull down, affinity chromatography technology, biochemical)
MED29
MED1
Gene Name
mediator complex subunit 29
mediator complex subunit 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Mediator Complex
Chromatin
Nucleus
Nucleoplasm
Nucleolus
Membrane
Mediator Complex
Protein-DNA Complex
Molecular Function
Protein Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity
Core Promoter Binding
RNA Polymerase II Transcription Cofactor Activity
Chromatin Binding
Transcription Cofactor Activity
Transcription Coactivator Activity
Receptor Activity
Protein Binding
Transcription Factor Binding
Ligand-dependent Nuclear Receptor Binding
Estrogen Receptor Binding
Ligand-dependent Nuclear Receptor Transcription Coactivator Activity
Thyroid Hormone Receptor Coactivator Activity
Chromatin DNA Binding
Nuclear Hormone Receptor Binding
Mediator Complex Binding
Vitamin D Receptor Binding
Retinoic Acid Receptor Binding
Peroxisome Proliferator Activated Receptor Binding
Thyroid Hormone Receptor Binding
LBD Domain Binding
Biological Process
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Cell Morphogenesis
Angiogenesis
Liver Development
Embryonic Placenta Development
Lens Development In Camera-type Eye
Thyroid Hormone Mediated Signaling Pathway
Ventricular Trabecula Myocardium Morphogenesis
Retinal Pigment Epithelium Development
Regulation Of Transcription From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase II Promoter
Thyroid Hormone Generation
Androgen Biosynthetic Process
Brain Development
Lactation
Gene Expression
Positive Regulation Of Gene Expression
Negative Regulation Of Keratinocyte Proliferation
Keratinocyte Differentiation
Monocyte Differentiation
Intracellular Steroid Hormone Receptor Signaling Pathway
Androgen Receptor Signaling Pathway
Organ Regeneration
Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Positive Regulation Of Protein Import Into Nucleus, Translocation
Positive Regulation Of Mammary Gland Epithelial Cell Proliferation
Embryonic Heart Tube Development
Embryonic Hindlimb Morphogenesis
Embryonic Hemopoiesis
Peroxisome Proliferator Activated Receptor Signaling Pathway
Cellular Response To Hepatocyte Growth Factor Stimulus
Megakaryocyte Development
MRNA Transcription From RNA Polymerase II Promoter
Negative Regulation Of Apoptotic Process
Cellular Lipid Metabolic Process
Small Molecule Metabolic Process
Fat Cell Differentiation
Positive Regulation Of Keratinocyte Differentiation
Negative Regulation Of Neuron Differentiation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Erythrocyte Development
Enucleate Erythrocyte Development
Regulation Of Cell Cycle
Positive Regulation Of Interferon-gamma-mediated Signaling Pathway
Mammary Gland Branching Involved In Thelarche
Mammary Gland Branching Involved In Pregnancy
Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation
Positive Regulation Of G0 To G1 Transition
ERK1 And ERK2 Cascade
Regulation Of Vitamin D Receptor Signaling Pathway
Cellular Response To Epidermal Growth Factor Stimulus
Cellular Response To Steroid Hormone Stimulus
Cellular Response To Thyroid Hormone Stimulus
Positive Regulation Of Receptor Activity
Positive Regulation Of Hepatocyte Proliferation
Regulation Of RNA Biosynthetic Process
Pathways
PPARA activates gene expression
Fatty acid, triacylglycerol, and ketone body metabolism
Metabolism of lipids and lipoproteins
Transcriptional regulation of white adipocyte differentiation
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
PPARA activates gene expression
Organelle biogenesis and maintenance
Fatty acid, triacylglycerol, and ketone body metabolism
Metabolism of lipids and lipoproteins
Nuclear Receptor transcription pathway
REV-ERBA represses gene expression
RORA activates circadian gene expression
Mitochondrial biogenesis
Regulation of cholesterol biosynthesis by SREBP (SREBF)
Generic Transcription Pathway
Transcriptional regulation of white adipocyte differentiation
YAP1- and WWTR1 (TAZ)-stimulated gene expression
Activation of gene expression by SREBF (SREBP)
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Transcriptional activation of mitochondrial biogenesis
BMAL1:CLOCK,NPAS2 activates circadian gene expression
Orphan transporters
Drugs
Diseases
GWAS
Protein-Protein Interactions
9 interactors:
MED1
MED12
MED13
MED14
MED17
MED20
MED21
MED9
USP47
42 interactors:
AR
BRCA1
CTDP1
ESR1
ESR2
EZH2
GABPA
GATA1
GATA3
GATA4
GATA6
GJB5
HNF4A
KIF1A
MDM2
MED12
MED14
MED25
MED29
MED8
MED9
MYC
NCOA6
NR1H2
NR1I3
NR3C1
NR4A1
PIN1
PPARA
PPARG
PPARGC1A
RARA
RORA
RXRA
RXRB
SREBF1
THRA
THRB
TP53
VDR
YWHAH
YWHAQ
Entrez ID
55588
5469
HPRD ID
13748
05055
Ensembl ID
ENSG00000063322
ENSG00000125686
Uniprot IDs
B4DUA7
Q9NX70
Q15648
PDB IDs
1RJK
1RK3
1RKG
1RKH
2O4J
2O4R
2ZFX
3A2H
3AUN
3VJS
3VJT
3VRT
3VRU
3VRV
3VRW
3W5P
3W5Q
3W5R
3W5T
Enriched GO Terms of Interacting Partners
?
Androgen Receptor Signaling Pathway
Transcription Initiation From RNA Polymerase II Promoter
Intracellular Steroid Hormone Receptor Signaling Pathway
DNA-templated Transcription, Initiation
Transcription From RNA Polymerase II Promoter
Intracellular Receptor Signaling Pathway
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
RNA Biosynthetic Process
Stem Cell Maintenance
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
RNA Metabolic Process
Stem Cell Development
Gene Expression
Nitrogen Compound Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Negative Regulation Of Cell Differentiation
Stem Cell Differentiation
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Positive Regulation Of Cellular Biosynthetic Process
Biosynthetic Process
Regulation Of Metabolic Process
Axis Elongation
Positive Regulation Of Cellular Metabolic Process
Regulation Of Cell Differentiation
Cell Development
Base-excision Repair
Thyroid Hormone Mediated Signaling Pathway
Positive Regulation Of Metabolic Process
Cellular Metabolic Process
Developmental Growth Involved In Morphogenesis
Enucleate Erythrocyte Development
Positive Regulation Of Interferon-gamma-mediated Signaling Pathway
Positive Regulation Of G0 To G1 Transition
Axis Elongation Involved In Somitogenesis
Depyrimidination
Regulation Of Organ Morphogenesis
Transcription Initiation From RNA Polymerase II Promoter
Intracellular Receptor Signaling Pathway
Transcription From RNA Polymerase II Promoter
DNA-templated Transcription, Initiation
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Steroid Hormone Mediated Signaling Pathway
Positive Regulation Of Gene Expression
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
Transcription, DNA-templated
Hormone-mediated Signaling Pathway
Response To Steroid Hormone
Cellular Response To Steroid Hormone Stimulus
RNA Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Cellular Response To Hormone Stimulus
Response To Hormone
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Cellular Response To Lipid
Response To Lipid
Regulation Of Transcription, DNA-templated
RNA Metabolic Process
Response To Organic Cyclic Compound
Regulation Of Nucleic Acid-templated Transcription
Cellular Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Cellular Response To Organic Cyclic Compound
Macromolecule Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Metabolic Process
Gene Expression
Intracellular Steroid Hormone Receptor Signaling Pathway
Cellular Response To Organic Substance
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Response To Organic Substance
Negative Regulation Of Transcription, DNA-templated
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Regulation Of Metabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Cellular Metabolic Process
Tagcloud
?
adam9
aurka
birc5
c11orf30
ccne1
cdc6
cdh1
cpd
devoid
emsy
esr1
fgfr1
holland
ikbkb
mapt
mathematical
meaning
microdissection
mlpa
mrc
mtdh
multiplex
numerical
p078
prdm14
qiagen
salsa
top2a
traf4
Tagcloud (Difference)
?
adam9
aurka
birc5
c11orf30
ccne1
cdc6
cdh1
cpd
devoid
emsy
esr1
fgfr1
holland
ikbkb
mapt
mathematical
meaning
microdissection
mlpa
mrc
mtdh
multiplex
numerical
p078
prdm14
qiagen
salsa
top2a
traf4
Tagcloud (Intersection)
?