DNAH3 and IVL

		DNAH3	IVL
Description		dynein axonemal heavy chain 3	involucrin
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Axonemal Dynein Complex Microtubule Cilium Dynein Complex Inner Dynein Arm Cell Projection 9+2 Motile Cilium	Cornified Envelope Cytoplasm Centrosome Cytosol Nuclear Body Extracellular Exosome
	Molecular Function	Nucleotide Binding Microtubule Motor Activity ATP Binding Minus-end-directed Microtubule Motor Activity Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding	Protein Binding
	Biological Process	Cilium Movement Microtubule-based Movement Inner Dynein Arm Assembly Cilium-dependent Cell Motility Cilium Movement Involved In Cell Motility	Response To UV-B Peptide Cross-linking Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Keratinocyte Differentiation Keratinization
Pathways			Formation of the cornified envelope Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Drugs
Diseases
GWAS		Diastolic blood pressure ( 27841878) Eosinophil count ( 32888494) Immune reponse to smallpox (secreted IL-10) ( 22610502) Plateletcrit ( 32888494) Resting-state electroencephalogram vigilance ( 29703947) Serum uric acid levels ( 29559957) Systolic blood pressure ( 27841878)	Asthma ( 31619474) Vitamin D levels ( 26704534)
Interacting Genes			10 interacting genes: ACD CRK CSTA DSP EVPL KRT1 LORICRIN POT1 SPRR3 UCHL5
Entrez ID		55567	3713
HPRD ID		04513	00931
Ensembl ID		ENSG00000158486	ENSG00000163207
Uniprot IDs		A0A8V8TLI9 B4E1S1 Q8TD57	P07476
PDB IDs		8J07
Enriched GO Terms of Interacting Partners?		Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Dentin Mineralization Response To Silver Ion Exonuclease Activity Response To Antipsychotic Drug Action Potential Initiation Memory T Cell Activation	Peptide Cross-linking Cornified Envelope Keratinocyte Differentiation Epidermal Cell Differentiation Keratinization Epidermis Development Telomere Assembly Epithelial Cell Differentiation Shelterin Complex Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Positive Regulation Of Telomere Maintenance Nuclear Telomere Cap Complex Wound Healing Telomere Capping Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Telomere Maintenance Regulation Of DNA Strand Elongation Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Organelle Organization Telomere Organization Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Via Telomerase RNA-templated DNA Biosynthetic Process Developmental Process Intermediate Filament Desmosome Telomeric DNA Binding Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Structural Molecule Activity Response To Stress Negative Regulation Of Telomere Maintenance Cytoskeleton Organization Response To Wounding Protein Modification Process Regulation Of Telomere Maintenance Via Telomerase Endopeptidase Inhibitor Activity Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Via Telomere Lengthening Ciliary Neurotrophic Factor Binding Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Structural Constituent Of Skin Epidermis Positive Regulation Of DNA Metabolic Process Macromolecule Metabolic Process
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