MRM3 and AIG1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MRM3	AIG1
Description		mitochondrial rRNA methyltransferase 3	androgen induced 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix	Plasma Membrane Endomembrane System Membrane
	Molecular Function	RNA Binding Protein Binding Methyltransferase Activity RNA Methyltransferase Activity Transferase Activity Identical Protein Binding RRNA (guanosine-2'-O-)-methyltransferase Activity	Protein Binding Hydrolase Activity
	Biological Process	RRNA 2'-O-methylation RRNA Processing RNA Processing Methylation	Lipid Metabolic Process Long-chain Fatty Acid Catabolic Process
Pathways		rRNA modification in the mitochondrion
Drugs
Diseases
GWAS			Acute lymphoblastic leukemia (childhood) ( 22076464) Carotid intima media thickness ( 30510157) Daytime sleep phenotypes ( 27126917) Diffusing capacity of carbon monoxide ( 30694715) Pulse pressure ( 27841878 30578418)
Interacting Genes		16 interacting genes: AIG1 APP ARLN BTN2A2 FBXO7 FHL3 GAD2 GALNT2 JAGN1 MIP OGT SCARF1 SHANK3 TNF UBIAD1 ZFPL1	54 interacting genes: APOD APOL2 AQP6 AQP9 ARL13B ASGR2 BCL2L13 BIK CCR9 CD53 CISD2 CLDN7 CPLX4 CYB5R3 CYBC1 ERGIC3 FAM209A FNDC9 FZD7 GLP1R GOLM1 GPR152 GPR35 GPX8 HIBADH HSD17B13 IER3IP1 KCNJ6 KIR2DL3 LAPTM5 LEUTX LIME1 LMNA LYVE1 MC4R MFF MRM3 PDZK1IP1 PSCA RCHY1 SAR1A SEC22B SLC10A6 SLC34A2 SLC7A14 STOM STX1A THAP4 THBD TMEM106C TMEM80 TMX2 VAMP3 VAPB
Entrez ID		55178	51390
HPRD ID		15266	16346
Ensembl ID		ENSG00000171861	ENSG00000146416
Uniprot IDs		Q9HC36	A0A2R8YCJ8 Q5THU2 Q9NVV5
PDB IDs		7OI6
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Proteolysis Amyloid-beta Complex Negative Regulation Of Blood Circulation Growth Cone Lamellipodium Neuron Projection Organization Positive Regulation Of Nitric Oxide Biosynthetic Process Negative Regulation Of MiRNA Transcription Regulation Of Synapse Organization Membrane Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Response To Calcium Ion Positive Regulation Of Excitatory Postsynaptic Potential Amylin Binding Neuron Maturation Positive Regulation Of Toll Signaling Pathway Regulation Of Long-term Synaptic Potentiation Regulation Of Amyloid-beta Clearance Positive Regulation Of Long-term Synaptic Potentiation Astrocyte Activation Positive Regulation Of Synaptic Transmission Positive Regulation Of Developmental Process Positive Regulation Of Membrane Protein Ectodomain Proteolysis Dendrite Development Microglial Cell Activation Positive Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Nervous System Process Positive Regulation Of Nitric Oxide Metabolic Process Regulation Of Membrane Protein Ectodomain Proteolysis Neuron Remodeling Regulation Of Generation Of Precursor Metabolites And Energy Leukocyte Activation Involved In Inflammatory Response Negative Regulation Of Bile Acid Secretion Positive Regulation Of Translational Initiation By Iron Positive Regulation Of Interleukin-33 Production Response To Gram-negative Bacterium Positive Regulation Of Translational Initiation Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Branching Involved In Lung Morphogenesis Response To Monosaccharide Response To Carbohydrate Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Vitamin K Biosynthetic Process Menaquinone Biosynthetic Process Modulation Of Excitatory Postsynaptic Potential Cellular Response To Amyloid-beta	Membrane Golgi Vesicle Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Plasma Membrane
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