ARHGEF10L and ANXA9

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		ARHGEF10L	ANXA9
Gene Name		Rho guanine nucleotide exchange factor (GEF) 10-like	annexin A9
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Cytosol Cell Surface Extracellular Vesicular Exosome
	Molecular Function	Rho Guanyl-nucleotide Exchange Factor Activity	Phosphatidylserine Binding Calcium Ion Binding Protein Binding Phospholipid Binding Calcium-dependent Phospholipid Binding Acetylcholine Receptor Activity Protein Homodimerization Activity
	Biological Process	Positive Regulation Of Rho GTPase Activity	Synaptic Transmission Single Organismal Cell-cell Adhesion
Pathways
Drugs
Diseases
GWAS		Basal cell carcinoma ( 18849993) Obesity-related traits ( 23251661) Response to hepatitis C treatment ( 22095909)	Chronic kidney disease ( 20383146) Melanoma ( 21926416 21983785) Rhegmatogenous retinal detachment ( 23585552)
Protein-Protein Interactions		4 interactors: ANXA9 DRAP1 NR4A1 SCN2A	3 interactors: APP ARHGEF10L NDUFA4L2
Entrez ID		55160	8416
HPRD ID		07679	11938
Ensembl ID		ENSG00000074964	ENSG00000143412
Uniprot IDs		Q5VXI4 Q9HCE6	O76027
PDB IDs
Enriched GO Terms of Interacting Partners?		Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress	Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling SREBP Signaling Pathway Response To Sterol Depletion Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Hydrolase Activity Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Neuron Recognition RNA Polyadenylation Positive Regulation Of Transcription, DNA-templated Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Positive Regulation Of Stress Fiber Assembly Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Actin Filament Bundle Assembly Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Catalytic Activity Positive Regulation Of Gene Expression Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Regulation Of Stress Fiber Assembly Visual Behavior Neuron Death Platelet Degranulation Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuromuscular Process Controlling Balance Synapse Assembly
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